Interesting facts
Interesting Facts About 4-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)phenol
This compound, commonly referred to as a member of the phenolic family, has garnered attention due to its unique structure and potential applications in various fields. Here are some fascinating aspects worth noting:
- Multi-functional Nature: The presence of both hydroxyl groups and an amine functional group in its structure makes this compound a versatile player in organic synthesis, potentially acting as both a nucleophile and an electrophile.
- Biological Relevance: Phenolic compounds are known for their significant role in biological systems, particularly as antioxidants. This compound’s unique substituents may enhance its efficacy in neutralizing free radicals, making it a candidate for studying health benefits.
- Potential Pharmaceutical Applications: Research into compounds like this has revealed their potential in drug development. The structural features suggest that it could serve as a scaffold for creating new therapeutic agents in treating various diseases.
- Presence of tert-butyl Group: The tert-butyl group, characterized by its bulky nature, can significantly influence the compound's steric effects and stability, which is critical when considering reactivity in different environments.
- Research Interest: The complexity of its structure has made it an interesting subject for chemists focusing on synthetic routes and mechanisms. The challenge of synthesizing such compounds often leads to improved strategies and techniques in organic chemistry.
In the world of chemistry, the exploration of compounds like 4-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)phenol not only fuels curiosity but also paves the way for innovations in material science and medicinal chemistry. As a future-centered chemist, understanding these intricate details can inspire new discoveries and applications.
Synonyms
Salbutamol
albuterol
18559-94-9
Proventil
Ventoline
Broncovaleas
dl-Albuterol
dl-Salbutamol
Salbutamolum
Asthalin
Cobutolin
Salbulin
Salbuvent
Saventol
Aerolin
Asmaven
Spreor
Asmol
Ventolin Inhaler
Sultanol
Sultanol N
Ventolin
Proventil HFA
Volmax
Butohaler
Butovent
Dilatamol
Farcolin
Gerivent
Grafalin
Libretin
Novosalmol
Pneumolat
Respolin
Salbetol
Salbuhexal
Salbupur
Salbusian
Salbutalan
Salbutan
Salbutol
Salbuven
Sallbupp
Salmaplon
Servitamol
Suprasma
Tobybron
Vencronyl
Ventamol
Ventilan
Ventiloboi
Almotex
Anebron
Asmadil
Asmanil
Asmasal
Asmatol
Asmidon
Bronter
Bugonol
Butamol
Butotal
Medolin
Parasma
Respax
Sabutal
Salbron
Salomol
Salvent
Theosal
Zaperin
Bumol
Mozal
Suxar
Alti-Salbutamol
Broncho-Spray
Salbu-Fatol
Buto-Asma
Asmol Uni-Dose
Proventil Inhaler
Salbu-BASF
Ventodisks
4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol
Volare easi-breathe
Arubendol-Salbutamol
Buventol
Salamol
Volare albuterol HFA
Salbutamol sulfate
Airomir
Etinoline
Eolene
AH 3365
Salbutamolum [INN-Latin]
ALBUTEROL (+/-)
4-(2-(tert-Butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol
rac Albuterol
alpha-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha'-diol
HSDB 7206
SCH-13949W
UNII-QF8SVZ843E
2-(tert-Butylamino)-1-(4-hydroxy-3-hydroxymethylphenyl)ethanol
EINECS 242-424-0
QF8SVZ843E
MFCD00148978
NSC-757417
BRN 2213614
CHEBI:2549
1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-alpha1,alpha3-diol
DTXSID5021255
alpha'-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha'-diol
DL-N-tert-Butyl-2-(4-hydroxy-3-hydroxymethylphenyl)-2-hydroxyethylamine
SCH 13949W
Albuterol [USAN:USP]
Proventil (TN)
4-Hydroxy-3-hydroxymethyl-alpha-((tert-butylamino)methyl)benzyl alcohol
alpha(sup 1)-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha'-diol
DTXCID001255
d,l-Salbutamol
35763-26-9
(l)-albuterol
EC 242-424-0
Ventalin inhaler
m-Xylene-alpha,alpha'-diol, alpha-((tert-butylamino)methyl)-4-hydroxy-
1,3-Benzenedimethanol, alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-
NSC 757417
Albuterol [USAN]
NCGC00015955-09
Solbutamol
Albuterol (USAN:USP)
m-Xylene-alpha,alpha'-diol, alpha'-((tert-butylamino)methyl)-4-hydroxy-
Salbutamolum (INN-Latin)
1,3-Benzenedimethanol, .alpha.1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
4-{2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
ALBUTEROL (USP-RS)
ALBUTEROL [USP-RS]
SALBUTAMOL (MART.)
SALBUTAMOL [MART.]
1,3-Benzenedimethanol, alpha(sup 1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-
SALBUTAMOL (EP IMPURITY)
SALBUTAMOL [EP IMPURITY]
ALBUTEROL (USP MONOGRAPH)
ALBUTEROL [USP MONOGRAPH]
SALBUTAMOL (EP MONOGRAPH)
SALBUTAMOL [EP MONOGRAPH]
Albuterol (USP)
148563-15-9
Salbutamol (hemisulfate)
SR-01000075161
salbutamolo
racemic salbutamol
Salamol EB
2-t-Butylamino-1-(4-hydroxy-3-hydroxy-3-hydroxymethyl)phenylethanol
alpha1-
Prestwick_665
CAS-18559-94-9
Salbutamol Free Base
(+/-)-salbutamol
(R)-Albuterol;(R)-Salbutamol;Levosalbutamol
Salbutamol,(+/-)
Venetlin (Salt/Mix)
Salbutamol (Standard)
Spectrum_000200
Albuterol (hemisulfate);AH-3365 (hemisulfate)
ALBUTEROL [MI]
Salbutamol [INN:BAN]
ALBUTEROL [HSDB]
SALBUTAMOL [INN]
Prestwick0_000198
Prestwick1_000198
Prestwick2_000198
Prestwick3_000198
Spectrum2_001350
Spectrum4_000887
Spectrum5_001059
ALBUTEROL [VANDF]
CHEMBL714
S 8260
SCHEMBL4913
SALBUTAMOL [WHO-DD]
SALBUTAMOL [WHO-IP]
Lopac0_001090
Lopac0_001098
BSPBio_000155
GTPL558
KBioGR_001294
KBioSS_000680
DivK1c_000943
SPECTRUM1500677
Albuterol - Bio-X trade mark
SPBio_001539
SPBio_002076
BPBio1_000171
SGCUT00011
ALBUTEROL [ORANGE BOOK]
SCHEMBL10025126
BCBcMAP01_000116
BDBM25769
HMS502P05
HY-B1037R
KBio1_000943
KBio2_000680
KBio2_003248
KBio2_005816
4-hydroxy-3-hydroxymethyl-alpha-
NINDS_000943
Bio1_000446
Bio1_000935
Bio1_001424
HMS1568H17
HMS1921C04
HMS2089I19
HMS2092I08
HMS2095H17
HMS3712H17
HMS3886I08
KUC106739N
Pharmakon1600-01500677
4-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)phenol
BCP28423
d,l-Salbutamol, 1mg/ml in Ethanol
HY-B1037
Salbutamol-(tert-butyl-d9) acetate
SALBUTAMOLUM [WHO-IP LATIN]
to_000081
Tox21_110266
Tox21_200800
4-{2-[(tert-butyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
CCG-39288
NSC757417
PDSP1_000623
PDSP2_000620
s5494
AKOS007930174
Tox21_110266_1
CS-4556
DB01001
FA61527
KS-5209
SB19749
SDCCGSBI-0051060.P006
IDI1_000943
SMP1_000268
NCGC00015955-04
NCGC00015955-05
NCGC00015955-06
NCGC00015955-07
NCGC00015955-08
NCGC00015955-10
NCGC00015955-11
NCGC00015955-12
NCGC00015955-13
NCGC00015955-14
NCGC00015955-16
NCGC00015955-28
NCGC00024698-02
NCGC00024698-03
NCGC00024698-04
NCGC00024698-05
NCGC00024698-06
NCGC00024698-07
NCGC00258354-01
AC-10286
BA164143
KSC-11-222-1
Salbutamol 100 microg/mL in Acetonitrile
SBI-0051060.P005
AB00052154
EU-0101090
NS00000415
VU0243312-5
D02147
EN300-365894
F15026
Salbutamol, VETRANAL(TM), analytical standard
AB00052154-08
AB00052154-09
AB00052154_10
AB00052154_11
L000531
Q410358
SR-01000075161-3
SR-01000075161-4
SR-01000075161-5
SR-01000075161-8
BRD-A88254928-001-04-6
BRD-A88254928-001-05-3
BRD-A88254928-001-07-9
BRD-A88254928-065-04-1
SR-01000075161-11
Z2301287926
Salbutamol, British Pharmacopoeia (BP) Reference Standard
Salbutamol, European Pharmacopoeia (EP) Reference Standard
Albuterol, United States Pharmacopeia (USP) Reference Standard
2-(tert-Butylamino)-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanol
4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol #
1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-.alpha.1,.alpha.3-diol
4-Hydroxy-3-hydroxymethyl-.alpha.-((tert-butylamino)methyl)benzyl alcohol
Albuterol; 4-[2-(tert-Butylamino)-1-hydroxy-ethyl]-2-methylol-phenol
alpha-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-alpha,alpha1-diol
.alpha.'-((tert-Butylamino)methyl)-4-hydroxy-m-xylene-.alpha.,.alpha.'-diol
.alpha.1'-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol, hemisulfate
.alpha.1-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-.alpha.,.alpha.'-diol
?(1)-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol;(+/-)-Salbutamol
1,3-Benzenedimethanol, .alpha.(1)-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
m-Xylene-.alpha.,.alpha.'-diol, .alpha.'-((tert-butylamino)methyl)-4-hydroxy-
m-Xylene-.alpha.,.alpha.-diol, .alpha.-1-((tert-butylamino)methyl)-4-hydroxy-
(+/-)-1,3-BENZENEDIMETHANOL, .ALPHA.(SUP 1)-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-4-HYDROXY-
1,3-BENZENEDIMETHANOL, .ALPHA.(SUP 1)-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-4-HYDROXY-
1,3-Benzenedimethanol, a1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (S)-, sulfate (2
242-424-0
Solubility of 4-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)phenol
The solubility of 4-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)phenol, with the chemical formula C12H19NO3, exhibits interesting characteristics influenced by its functional groups.
Key factors affecting its solubility include:
As a result, this compound may show good solubility in organic solvents while demonstrating varying degrees of solubility in water. Understanding the overall interaction of these components can provide insights into the compound's behavior in various applications.
In summary, one could say that "the solubility is not simply black or white; it's a spectrum defined by molecular interactions."