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Propylhexedrine

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Identification
Molecular formula
C12H19NO
CAS number
102-97-6
IUPAC name
4-[2-(dipropylamino)ethyl]benzene-1,2-diol
State
State

Propylhexedrine is generally in a liquid state at room temperature. It has a relatively low melting point and a relatively high boiling point, making it volatile under certain conditions.

Melting point (Celsius)
-9.00
Melting point (Kelvin)
264.15
Boiling point (Celsius)
220.50
Boiling point (Kelvin)
493.65
General information
Molecular weight
179.30g/mol
Molar mass
179.2990g/mol
Density
0.9333g/cm3
Appearence

Propylhexedrine is typically a colorless liquid or in some formulations a clear, volatile liquid. It may have a faint amine-like odor due to its chemical structure comprising an amine group.

Comment on solubility

Solubility of 4-[2-(dipropylamino)ethyl]benzene-1,2-diol

The solubility of the compound 4-[2-(dipropylamino)ethyl]benzene-1,2-diol (C12H19NO) can be characterized by several important factors:

  • Polarity: The presence of hydroxyl (-OH) groups in the structure contributes to the compound's polarity, which generally enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability of the hydroxyl groups to engage in hydrogen bonding can further facilitate solubility in aqueous environments. These groups can interact with water molecules, effectively increasing overall solubility.
  • Hydrophobic Regions: However, the dipropylamino group introduces hydrophobic characteristics, which might limit solubility in highly polar solvents.
  • Solvent Compatibility: This compound is likely to exhibit variable solubility depending on the solvent used, being more soluble in organic solvents compared to water due to the presence of larger hydrophobic alkyl groups.
  • Temperature Influence: Solubility can also change with temperature; typically, increasing the temperature may enhance the solubility of solids.

In summary, the solubility of 4-[2-(dipropylamino)ethyl]benzene-1,2-diol is influenced by its unique combination of polar and nonpolar characteristics, making it soluble in some solvents while potentially limiting its solubility in others.

Interesting facts

Interesting Facts about 4-[2-(Dipropylamino)ethyl]benzene-1,2-diol

4-[2-(Dipropylamino)ethyl]benzene-1,2-diol is a fascinating compound with intriguing applications in various fields, particularly in medicinal chemistry and pharmacology. Here are some noteworthy aspects:

  • Structure and Function: The compound features a benzene ring substituted with a diol group and an aliphatic dipropylamino chain, which contributes to its overall hydrophobic character and biological activity.
  • Pharmacological Importance: Compounds like 4-[2-(dipropylamino)ethyl]benzene-1,2-diol are often explored for their interactions with neurotransmitter systems, particularly serotonin and norepinephrine, making them potential candidates for antidepressant drugs.
  • Drug Design: The synthesis and modification of such compounds play a significant role in drug design, allowing chemists to engineer molecules that can selectively target specific physiological pathways.
  • Research Applications: This compound may serve as a useful tool in biochemical research, elucidating the role of various receptors and signaling pathways in the nervous system.
  • Safety and Regulation: Like many chemical compounds, it is important to consider the safety profile and regulatory status, especially when adapted for therapeutic use, ensuring efficacy while minimizing potential side effects.

“Understanding compounds like 4-[2-(dipropylamino)ethyl]benzene-1,2-diol not only enhances our comprehension of chemical interactions but also paves the way for innovative therapeutic solutions.”

This compound exemplifies how intricate molecular structures can lead to significant biological implications, showcasing the beauty and complexity found in the world of chemistry.

Synonyms
N,N-di-n-propyldopamine
DPDA
66185-61-3
4-[2-(dipropylamino)ethyl]benzene-1,2-diol
N,N-Dipropyldopamine
CP598ZU72P
4-(2-(Dipropylamino)ethyl)-1,2-benzenediol
CHEMBL15564
DTXSID50216371
N-Dipropyldopamine hydrobromide
Lopac-D-031
Biomol-NT_000072
UNII-CP598ZU72P
Lopac0_000465
SCHEMBL467093
BPBio1_001388
CHEBI:93446
DTXCID50138862
BDBM50019396
PDSP1_000638
PDSP2_000633
CCG-204557
SDCCGSBI-0050450.P002
NCGC00015296-01
NCGC00015296-02
NCGC00015296-03
NCGC00015296-04
NCGC00015296-06
NCGC00162162-01
NCGC00162162-02
4-(2-Dipropylamino-ethyl)-benzene-1,2-diol
BRD-K82577285-001-01-7
Q27165143
4-[2-(dipropylamino)ethyl]-1,2-benzenediol, monohydrobromide
4-(2-Dipropylamino-ethyl)-benzene-1,2-diol (N,N-dipropyldopamine)