Paraxenol | Solubility of Things

Identification

Molecular formula

C₉H₁₃NO

CAS number

123-30-8

IUPAC name

4-(2-aminopropyl)phenol

State

At room temperature, 4-(2-Aminopropyl)phenol is typically found in a solid state, appearing as crystals or crystalline powder.

Melting point (Celsius)

59.00

Melting point (Kelvin)

332.15

Boiling point (Celsius)

282.00

Boiling point (Kelvin)

555.15

General information

Molecular weight

151.21g/mol

Molar mass

151.2070g/mol

Density

1.0512g/cm³

Appearence

4-(2-Aminopropyl)phenol appears as a white to off-white crystalline powder with a slight odor. It is often described in laboratory and industrial settings as a solid that, depending on conditions, might appear more amorphous.

Comment on solubility

Solubility of 4-(2-aminopropyl)phenol

4-(2-aminopropyl)phenol, with the chemical formula C₉H₁₃NO, exhibits interesting solubility characteristics that can be influenced by a variety of factors. Understanding its solubility is essential for various applications in chemistry and biology.

Key Solubility Features:

Polarity: Due to the presence of an amino group and a hydroxyl group, 4-(2-aminopropyl)phenol is a polar compound, which enhances its solubility in polar solvents.
Solvent Compatibility: This compound tends to dissolve well in water and alcohols, owing to hydrogen bonding capabilities attributed to its hydroxyl (-OH) and amine (-NH₂) groups.
Temperature Effects: Like many organic compounds, its solubility might increase with temperature, allowing for a higher degree of dissolving in solvents.

In practice, you may find that the incomplete solubility in non-polar solvents, such as hexane or chloroform, is quite typical for this type of compound. Therefore, when predicting solubility, it's valuable to remember that:

The functional groups largely dictate solubility behavior.
The environment (pH and temperature) can significantly impact its solubility.
Interactions with other components in a solution may also play a role, such as the presence of salts which can affect solute-solvent interactions.

In summary, the solubility of 4-(2-aminopropyl)phenol can be described as relatively good in polar solvents, driven by its molecular structure and functional groups, making it a useful compound in many chemical processes.

Interesting facts

Exploring 4-(2-aminopropyl)phenol

4-(2-aminopropyl)phenol, also known as phenylpropanolamine, is a fascinating compound that has garnered attention in both medicinal and chemical research due to its unique properties and applications. Here are some intriguing facts about this compound:

Pharmacological Significance: This compound has been primarily used as a decongestant and appetite suppressant, playing a role in the formulation of many over-the-counter medications.
Structural Brilliance: The presence of both an amino group and a phenolic structure allows it to interact with various biological pathways, making it a subject of interest in drug design.
Historical Context: 4-(2-aminopropyl)phenol was once widely used in weight-loss products and for managing nasal congestion, although regulatory changes have influenced its market availability.
Safety Concerns: The compound has been associated with certain health risks, particularly elevated blood pressure, leading to increased scrutiny and calls for consumer awareness.
Research Frontiers: Ongoing studies are investigating its mechanisms of action and potential alternatives, bridging the gap between chemistry and pharmacology.

As we continue to delve into the realms of medicinal chemistry, compounds like 4-(2-aminopropyl)phenol remind us of the intricate balance between chemical structure and biological activity.
Understanding its properties can lead to improved therapeutic strategies and enhanced safety profiles.

Synonyms

4-(2-Aminopropyl)phenol

hydroxyamphetamine

103-86-6

Hydroxyamfetamine

4-Hydroxyamphetamine

Norveritol

Pulsoton

Paredrine

p-HYDROXYAMPHETAMINE

Norpholedrine

Oxamphetamine

Oxamphetaminium

Oksamfetamin

Oxamfetamin

Paredrinex

Nov-Pholedrin

Phenol, 4-(2-aminopropyl)-

Paradrine

Pedrolon

p-(2-Aminopropyl)phenol

Phenol, p-(2-aminopropyl)-

DL-p-Hydroxyamphetamine

Phenol,4-(2-aminopropyl)-

1-p-Hydroxyphenyl-2-propylamine

dl-4-hydroxyamphetamine

2-Amino-1-(p-hydroxyphenyl)propane

.alpha.-Methyltyramine

NSC 170995

Hydroxyamfetamine [INN]

Hidroxianfetamina

alpha-Methyltyramine

p-Hydroxy-alpha-methylphenethylamine

Racemic p-hydroxyamphetamine

4-Hydroxy-alpha-methylphenethylamine

EINECS 203-152-8

FQR280JW2N

Hydroxyamfetamine [INN:BAN]

4-Hydroxy-.alpha.-methylphenethylamine

NSC-170995

BRN 2413849

DL-p-(2-Aminopropyl)phenol

HYDROXYAMPHETAMINE [MI]

1518-86-1

HYDROXYAMPHETAMINE [VANDF]

HYDROXYAMFETAMINE [WHO-DD]

3-13-00-01709 (Beilstein Handbook Reference)

p-Hydroxy-.alpha.-methylphenethylamine

(+/-)-P-(2-AMINOPROPYL)PHENOL

Hydroxyamphetamide

4-(2-aminopropyl)phenol;hydrobromide

UNII-FQR280JW2N

idrossiamfetamina

hydroxyamfetaminum

Predrolon (Salt/Mix)

Spectrum_001243

OH-A

Spectrum3_001037

Spectrum4_001174

Spectrum5_001674

(RS)-4-hydroxyamphetamine

Hydroxyamphetamine,(+/-)

WLN: Z3R DQ

CHEMBL1546

4-(2-amino-propyl)-phenol

BSPBio_002853

KBioGR_001807

KBioSS_001723

(+/-)-4-Hydroxyamphetamine

SCHEMBL125440

DTXSID3023134

BDBM81459

KBio2_001723

KBio2_004291

KBio2_006859

KBio3_002073

CHEBI:103855

AAA10386

HY-B1098

NSC_3651

1-(4-Hydroxyphenyl)propane-2-amine

NSC170995

PDSP1_001107

PDSP2_001091

AKOS000155358

AKOS017269170

CS-4687

DB09352

benzene, 1-(2-amino)propyl-4-hydroxy-

NCGC00178433-01

NCGC00178433-02

BS-13447

CAS_103-86-6

DB-229149

NS00006145

Phenol, p-(2-aminopropyl)-, (.+/-.)-

EN300-53926

Phenol, 4-(2-aminopropyl)-, (.+/-.)-

AB01563354_01

Q5955531

BRD-A80871782-004-01-0

BRD-A80871782-004-06-9

Z57102382

203-152-8