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6-Fluoronorepinephrine

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Identification
Molecular formula
C8H10FNO3
CAS number
1134542-39-7
IUPAC name
4-(2-amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol
State
State

At room temperature, 6-Fluoronorepinephrine is typically in a solid state, appearing as a white to off-white powder.

Melting point (Celsius)
246.00
Melting point (Kelvin)
519.15
Boiling point (Celsius)
360.50
Boiling point (Kelvin)
633.65
General information
Molecular weight
173.17g/mol
Molar mass
173.1550g/mol
Density
1.5400g/cm3
Appearence

6-Fluoronorepinephrine typically appears as a white to off-white solid powder. It may also appear as crystals depending on the purity and form of the compound.

Comment on solubility

Solubility of 4-(2-amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol

The solubility of the compound 4-(2-amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol (C8H10FNO3) is quite noteworthy due to its unique functional groups and molecular structure. This compound exhibits specific solubility characteristics based on the following considerations:

  • Polarity: The presence of hydroxyl (-OH) and amino (-NH2) groups increases polarity, enhancing solubility in polar solvents such as water.
  • Hydrogen bonding: The ability to form hydrogen bonds with solvent molecules significantly contributes to its aqueous solubility.
  • Alkyl chain presence: The ethyl group can affect solubility; while it adds some non-polar character, the overall molecule remains primarily polar due to functional groups.
  • Temperature influence: Generally, increased temperature can improve solubility for many organic compounds, which may also apply here.

In summary, this compound is likely to be soluble in polar solvents and potentially less so in non-polar environments. The structural features suggest that it will interact favorably with water, making it an interesting candidate for further studies in dissolution and solubility profiles.

Interesting facts

Exploring 4-(2-amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol

This intriguing compound, commonly referred to in the scientific community, boasts a rich array of characteristics and potential applications. Here are some captivating facts:

  • Pharmaceutical Potential: The presence of the amino and hydroxy groups in its structure suggests that this compound could exhibit noteworthy biological activity, particularly in the field of medicinal chemistry. Compounds with similar structures are often evaluated for their pharmacological properties.
  • Fluorine's Role: The inclusion of a fluorine atom is particularly interesting, as fluorine is known to enhance the metabolic stability of organic compounds. It can also significantly influence the lipophilicity of a molecule, potentially improving its bioavailability.
  • Phenolic Functionality: The benzene-1,2-diol moiety implies that this compound may display antioxidant activity, as phenolic compounds are known for their ability to scavenge free radicals. This raises exciting possibilities for its use in health-related products.
  • Environmental Considerations: The synthesis and degradation of such compounds can be studied to understand their environmental impact. The introduction of fluorine into organic molecules can impact their persistence and bioaccumulation in biological systems.

In the realm of chemical research, compounds like 4-(2-amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol serve as a reminder of the intricate connections between molecular structure and biological function. As scientists continue to explore this compound, we may uncover new pathways to innovation in pharmaceuticals and environmental science.

Synonyms
6-Fluoronorepinephrine
5-Fluoronorepinephrine
86820-21-5
4-(2-amino-1-hydroxyethyl)-5-fluorobenzene-1,2-diol
6-fluoro-noradrenaline
CHEMBL281232
6-fluoro-NE
(+/-)-6-Fluoronorepinephrine
4-(2-Amino-1-hydroxyethyl)-5-fluoro-1,2-benzenediol
Lopac0_000205
GTPL510
SCHEMBL1691820
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-5-fluoro-
4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol
CHEBI:125398
DTXSID301007133
BDBM50019061
CCG-204300
SDCCGSBI-0050193.P002
NCGC00015118-02
NCGC00015118-03
NCGC00162091-01
PD050452
L023960
Benzeneethanamine, 2-fluoro-.beta.,3,4-trihydroxy-
Q4641540
4-(2-Amino-1-hydroxyethyl)-5-fluoro-1,2-benzenediol #
(+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol
4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol(6-FNE)