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Peptide Fragment

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Identification
Molecular formula
C37H44N6O8S
CAS number
122758-99-8
IUPAC name
4-[(2-amino-1-benzyl-2-oxo-ethyl)amino]-3-[[2-[[2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]-4-oxo-butanoic acid
State
State

This compound is typically found in a solid state at room temperature. As a peptide fragment, it is often stored in a desiccated form to prevent degradation.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
647.75g/mol
Molar mass
647.7500g/mol
Density
1.3000g/cm3
Appearence

The compound typically appears as a white to off-white powder. It may vary depending on the level of hydration and the specific crystalline form.

Comment on solubility

Solubility of 4-[(2-amino-1-benzyl-2-oxo-ethyl)amino]-3-[[2-[[2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]-4-oxo-butanoic acid (C37H44N6O8S)

The solubility of the compound 4-[(2-amino-1-benzyl-2-oxo-ethyl)amino]-3-[[2-[[2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]-4-oxo-butanoic acid is influenced by its complex structure and functional groups. Key factors affecting its solubility include:

  • Hydrophobic Interactions: The presence of several benzyl groups contributes to increased hydrophobicity, potentially limiting solubility in polar solvents.
  • Polar Functional Groups: Amino (-NH2) and carbonyl (C=O) groups promote interactions with water, enhancing solubility in specific conditions.
  • pH Sensitivity: The acidic nature of the compound may lead to changes in solubility based on solution pH, potentially increasing solubility in basic conditions.
  • Solvent Choice: Solubility may vary significantly with different solvents; it is generally more soluble in organic solvents compared to aqueous environments.

Overall, it can be stated that the solubility of this compound is moderate and heavily dependent on environmental factors and the solvent used. Understanding its solubility behavior is crucial for its applications in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 4-[(2-amino-1-benzyl-2-oxo-ethyl)amino]-3-[[2-[[2-(benzyloxycarbonylamino)-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]-4-oxo-butanoic acid

This intriguing compound is a fine example of the complexity often found in medicinal chemistry. Its structure includes several functional groups, making it a potential candidate for various biological activities. Here are some engaging points worth exploring:

  • Wide-ranging Applications: With features such as amino groups, a benzenoid system, and a sulfonyl moiety, this compound can interact with numerous biological pathways, potentially leading to therapeutic applications in cancer and metabolic disorders.
  • Structure-Activity Relationship (SAR): The diverse substituents on the backbone of this molecule can be systematically altered to optimize biological activity and reduce toxicity, a pivotal aspect in drug design.
  • Indole Derivative: The inclusion of an indole ring is not just a structural embellishment; indoles are known for their profound effects on biological systems, particularly in the area of neurotransmission and anti-cancer properties.
  • Customizable Synthesis: The lengthy and intricate synthesis pathway involved provides an exciting avenue for chemists to explore new synthetic methodologies and engage with complex organic transformations.

As the famous chemist Linus Pauling once stated, "The best way to have a good idea is to have a lot of ideas." Investigating compounds like this one epitomizes this philosophy, allowing chemists to brainstorm and innovate towards discovering effective medicines and understand complex biochemical mechanisms.

Furthermore, the potential lifescapes of this compound can also serve students as a case study in structure-property relationships, encouraging budding scientists to explore the multifaceted world of organic compounds and their biochemical roles.

Synonyms
SCHEMBL22590113
DTXSID10862797
Cbz-L-Trp-L-Met-L-Asp-L-Phe-NH2
NS00121046
G12233
N-[(benzyloxy)carbonyl]tryptophylmethionyl-alpha-aspartylphenylalaninamide