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Betamethasone dipropionate

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Identification
Molecular formula
C28H37FO7
CAS number
5593-20-4
IUPAC name
4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoic acid
State
State

At room temperature, betamethasone dipropionate is typically in a solid state. It is supplied in various topical formulations such as creams and ointments specifically designed for ease of application to the skin.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
390.70
Boiling point (Kelvin)
663.85
General information
Molecular weight
521.61g/mol
Molar mass
521.6100g/mol
Density
1.3150g/cm3
Appearence

Betamethasone dipropionate typically appears as a white to practically white crystalline powder. It is odorless and hygroscopic in nature. The compound is known for its stability under normal conditions but should be protected from light and moisture to maintain its efficacy in pharmaceutical formulations.

Comment on solubility

Solubility of 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoic acid

The solubility of the compound with the formula C28H37FO7 can be considered within the context of its structural complexity and the presence of functional groups. Here are some key points to consider:

  • Hydrophobic vs. Hydrophilic: The presence of multiple hydroxy (-OH) groups suggests that parts of the molecule can engage in hydrogen bonding, which generally increases solubility in polar solvents such as water.
  • Structural Features: The large hydrocarbon framework may contribute to significant hydrophobic characteristics, potentially leading to lower solubility in polar solvents.
  • Common Solvents: This compound may exhibit variable solubility in:
    • Water: Potentially low due to the hydrophobic parts.
    • Organic solvents: May dissolve better in organic solvents like ethanol or methanol due to structural compatibility.
  • Temperature Dependence: Solubility can often increase with temperature, which is an important consideration in practical applications.

In summary, the solubility of 4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoic acid is complex and will depend heavily on the solvent environment and temperature conditions. Understanding its solubility behavior is crucial for applications in pharmaceuticals and related fields where the mobility of the compound is of significant interest.

Interesting facts

Interesting Facts about 4-[2-(11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]-4-oxo-butanoic acid

This compound is part of a fascinating category known for its complex structure and potential therapeutic applications. Below are some intriguing aspects that highlight its significance:

  • Complex Structure: The intricate arrangement of its molecular framework suggests that it may exhibit unique reactivity and functionality. Specifically, the presence of multiple *hydroxyl* and *carbonyl* groups may contribute to its distinctive chemical behavior.
  • Potential Biological Activity: Compounds similar to this one often engage in significant biological activities. Interestingly, some derivatives are studied for their role in *anti-inflammatory* and *antioxidant* mechanisms, which hold potential in pharmacological applications.
  • Steroid-Like Character: Given its structural components, this compound may share characteristics with steroidal compounds. Steroids are known for their role in regulating biological processes, which raises questions about this compound's potential biological roles.
  • Ethoxy and Butanoic Acid Moieties: The ethoxy group in the structure provides potential for modifications, enhancing its solubility and bioavailability. Additionally, the presence of the butanoic acid segment could endow it with energy-related properties.
  • Synthetic Interest: Chemists are often intrigued by compounds with such elaborate structures as they can serve as important intermediates in the synthesis of more complex molecules. This makes them valuable in both industry and research scenarios.

As we delve deeper into understanding this compound, it serves as a reminder of the incredible complexity found in organic chemistry, showcasing not just the aesthetic charm of molecular design, but also the potential for discovery in the realms of medicine and beyond.

Synonyms
1231184-90-9
4-(2-{1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl}-2-oxoethoxy)-4-oxobutanoic acid
4-[(11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl)oxy]-4-oxobutanoic acid
CERAPP_12744
DTXSID20859234
BBL033641
STL372790
AKOS025247954
4-[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethoxy]-4-oxobutanoic acid
VS-12196
DB-045769
EN300-295974