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Epinephrine

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Identification
Molecular formula
C9H13NO3
CAS number
51-43-4
IUPAC name
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
State
State
Epinephrine is a solid at room temperature, usually found in crystal or powder form. It is slightly soluble in water.
Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
183.20g/mol
Molar mass
183.2040g/mol
Density
1.2831g/cm3
Appearence

Epinephrine appears as white crystals or a white, microcrystalline powder. It is often accompanied by a slight odor and may gradually darken upon exposure to air and light.

Comment on solubility

Solubility of 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol

The compound 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, with the chemical formula C9H13NO3, presents interesting solubility characteristics derived from its molecular structure.

  • Polar Nature: The presence of hydroxyl (-OH) groups suggests that this compound is likely polar, which enhances its ability to dissolve in polar solvents such as water.
  • Hydrogen Bonding: The hydroxyl groups can participate in hydrogen bonding, further increasing solubility in aqueous environments.
  • Amino Group Influence: The methylamino group may also contribute to increased stability in solution through additional polar interactions.

However, the actual solubility can vary based on environmental conditions, such as:

  • pH Levels: Changes in pH can affect the protonation state of the amino group, which may influence solubility.
  • Temperature: Higher temperatures often lead to increased solubility for many organic compounds.

In summary, while this compound is expected to be soluble in polar solvents, its solubility behavior can be significantly impacted by external factors such as pH and temperature. As noted, the structural features of 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol present a promising case for efficient solvation, particularly in biologically relevant contexts.

Interesting facts

Interesting Facts about 4-[1-Hydroxy-2-(methylamino)ethyl]benzene-1,2-diol

The compound 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, commonly referred to in the scientific community for its applications in various fields, boasts several fascinating aspects:

  • Biological Significance: This compound is structurally related to neurotransmitters such as dopamine. Its ability to interact with biological systems makes it a subject of interest in pharmacology and neuroscience.
  • Potential Therapeutic Uses: Due to its functional groups, it has been investigated for its potential effects in treating various conditions, particularly those related to mood and anxiety disorders, showcasing its significance in medicinal chemistry.
  • Synthesis: The synthesis of this compound involves intricate organic reactions, demonstrating the beauty of chemical transformations. It can serve as a great example for students learning about reaction mechanisms.
  • Research Opportunities: As a scientist, you might find opportunities in studying its metabolic pathways, understanding how it is processed in living organisms, or exploring derivative compounds that might enhance its effects.
  • Environmental Interaction: Investigating how this compound behaves in natural systems could provide insights into its environmental impact and stability, making it important for ecological studies.

A quote that exemplifies the importance of chemical compounds like 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol comes from Nobel Prize-winning chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." This compound is a testament to the wealth of knowledge waiting to be uncovered in the realm of chemistry.

In summary, the exploration of this compound not only enriches our understanding of organic chemistry but also opens doors to innovative therapeutic avenues and advances in synthetic methodologies.

Synonyms
DL-Adrenaline
329-65-7
dl-Epinephrine
Racepinephrine
Racepinefrine
Epirenamine
Epinephrine racemic
(+-)-Adrenaline
DL-Adrenalin
Racepinefrina
Racepinefrinum
L(-)-Epinephrine
(+-)-Epinephrine
4-(1-hydroxy-2-(methylamino)ethyl)benzene-1,2-diol
Vaponefrin
Epinephrine dl-
Epinephrine, dl-
Racemic Epinephrine
Epinephrine dl-form
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
(+/-)-adrenaline
2-(Methylamino)-1-(3,4-dihydroxyphenyl)ethanol
D-Epinephrine
rac Epinephrine
UNII-GR0L9S3J0F
Racemic adrenaline
EINECS 206-347-6
Racepinefrinum [INN-Latin]
GR0L9S3J0F
Adrenaline, racemic
Racepinefrina [INN-Spanish]
1-(3,4-Dihydroxy)phenyl-2-methylaminoethanol
Epinephrine, Racemic
BRN 2212160
CCRIS 8140
Racepinefrine [INN]
Racepinephrine [USP]
CHEBI:33568
CHEMBL1740
Micronefrin
1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-
DTXSID80858965
L-(-)-EPINEPHRINE
4-13-00-02927 (Beilstein Handbook Reference)
( )-Epinephrine
1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-
Racepinephrine (USP)
Racepinefrinum (INN-Latin)
Racepinefrina (INN-Spanish)
Micronephrine
MLS001333244
RACEPINEPHRINE (USP MONOGRAPH)
RACEPINEPHRINE [USP MONOGRAPH]
(+/-)-Epinephrine
(+/-)-Epinephrine;DL-Adrenaline;(+/-)-Adrenaline
SMR000058236
Epinepherine
DL-Adrenali
D,L-Epinephrine
Adrenaline,(S)
Epinephrine dl form
(plusmn)-adrenaline
(+-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(R,S)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzylalkohol
EPINEPHRINE,(+)
(.+/-.)-Adrenaline
(.+/-.)-Epinephrine
4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol #
Racepinephrine (USP/INN)
cid_5924
SCHEMBL3815
Hydrochloride, racepinephrine
NCIOpen2_000082
Lopac0_000522
GTPL509
RACEPINEFRINE [WHO-DD]
4-(1-Hydroxy-2-methylamino-ethyl)-benzene-1,2-diol
SGCUT00008
(-)-Epinephrine (+)-bitartrate salt;L-Adrenaline (+)-bitartrate salt
BDBM84342
DTXCID20196651
EPINEPHRINE DL-FORM [MI]
CHEBI:194548
(+/-)-Epinephrine, >=95%
HMS3259B19
HMS3656E12
1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, (+-)-
104655-05-2
AAA15005
BCP17220
HY-B0447
to_000046
AC-395
BBL028091
Benzyl alcohol, 3,4-dihydroxy-alpha-((methylamino)methyl)-, (+-)-
PDSP1_000587
PDSP2_000584
s2523
STL146338
AKOS005721043
CCG-204612
FE22735
NC00671
SDCCGSBI-0050505.P002
( inverted exclamation markA)-Adrenaline
NCGC00015417-02
NCGC00015417-03
NCGC00015417-16
NCGC00162177-01
( inverted exclamation markA)-Epinephrine
AS-12580
()-Epinephrine;DL-Adrenaline;()-Adrenaline
A0172
D05688
D88221
EN300-208482
AB00514461_07
L000877
4-(1-hydroxy-2-methylaminoethyl)benzene-1,2-diol
Q7279006
SR-01000075862-8
BRD-A07765530-001-05-6
BRD-A07765530-001-06-4
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, 1
9561B8BB-366F-4A33-B295-1C6E682AC6BB
(.+/-.)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
1,2-Benzenediol,4-[(1S)-1-hydroxy-2-(methylamino)ethyl]-
4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol;hydrochloride
(.+/-.)-3,4-Dihydroxy-.alpha.-[(methylamino)methyl]benzyl alcohol
1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (.+/-.)-
4-[2-(methylamino)-1-oxidanyl-ethyl]benzene-1,2-diol;hydrochloride
Benzyl alcohol, 3,4-dihydroxy-.alpha.-((methylamino)methyl)-, (.+/-.)-
BENZYL ALCOHOL, 3,4-DIHYDROXY-alpha-((METHYLAMINO)METHYL)-, (+/-)-
BENZYL ALCOHOL, 3,4-DIHYDROXY-.ALPHA.-((METHYLAMINO)METHYL)-, (+/-)-
InChI=1/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H
4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;DL-Adrenaline;(+/-)-3,4-Dihydroxy-?-[(methylamino)methyl]benzyl alcohol