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Ethylimidazolone

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Identification
Molecular formula
C9H14N2O2
CAS number
84112-00-7
IUPAC name
(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]tetrahydrofuran-2-one
State
State

At room temperature, Ethylimidazolone is typically a solid. It is stable under standard conditions and possesses notable chiral properties due to its stereocenters.

Melting point (Celsius)
52.30
Melting point (Kelvin)
325.45
Boiling point (Celsius)
138.50
Boiling point (Kelvin)
411.65
General information
Molecular weight
169.21g/mol
Molar mass
169.2060g/mol
Density
1.1890g/cm3
Appearence

The compound typically appears as a clear, colorless crystalline solid. It may have a distinct molecular structure when visualized under advanced microscopic techniques due to its chiral centers.

Comment on solubility

Solubility of (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]tetrahydrofuran-2-one

The solubility of (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]tetrahydrofuran-2-one, with the chemical formula C9H14N2O2, can be described as follows:

  • Polarity: This compound contains multiple functional groups, including the imidazole ring, which enhances its overall polarity. Consequently, it is likely to exhibit good solubility in polar solvents.
  • Solvent Compatibility: Due to its functional groups, it may be soluble in:
    • Water
    • Alcohols (e.g., ethanol, methanol)
    • Aqueous buffer solutions
  • Effects of Temperature: Like many organic compounds, its solubility can increase with temperature, making it more soluble in heated solvents.
  • Cation Interactions: The presence of nitrogen in the imidazole structure may allow interactions with cations, possibly enhancing its solubility in ionic solutions.

In summary, the solubility of (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]tetrahydrofuran-2-one is influenced by its polar characteristics and appropriate solvent interactions. Understanding its solubility profile is essential for applications in pharmaceutical formulations and other chemical processes.

Interesting facts

Interesting Facts about (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]tetrahydrofuran-2-one

This fascinating compound combines a unique structure with potential applications in various fields of chemistry and pharmacology. Here are some interesting aspects of (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]tetrahydrofuran-2-one:

  • Stereochemistry: The stereochemistry of this compound is particularly noteworthy. With specific configurations at the 3 and 4 positions, this compound can exhibit different biological activities, influencing its interaction with biological systems.

  • Imidazole Link: The presence of a 3-methylimidazol-4-yl group contributes to the compound's properties, particularly enhancing its potential as a ligand in coordination chemistry and medicinal chemistry. Imidazoles are known for their biological significance and roles in numerous enzymatic processes.

  • Tetrahydrofuran Ring: The tetrahydrofuran moiety provides a cyclic structure that is often associated with stability and reactivity, making it a valuable scaffold for further chemical modifications.

  • Pharmaceutical Potential: Given its structural characteristics, this compound holds promise in drug design. It can serve as a lead compound in the development of new pharmaceuticals targeting various diseases.

  • Research Interest: As a subject of academic research, compounds like this are often investigated for their potential effects in biochemistry and medicinal chemistry, providing insights into drug-receptor interactions.

  • Applied Chemistry: The versatile nature of this compound allows chemists to explore its use in organic synthesis and materials science, potentially leading to innovative applications.

In conclusion, (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]tetrahydrofuran-2-one showcases the intersection of organic chemistry and potential therapeutic applications, making it a compelling subject for further study in the scientific community.

Synonyms
pilocarpine
92-13-7
Pilokarpin
Pilocarpol
Syncarpine
Ocusert pilo
Pilocarpin
Spersacarpine
Pilokarpol
(+)-Pilocarpine
Ocusert pilo-20
Ocusert Pilo-40
Ocusert P 20
ocucarpine
Isoptocarpine
Pilocarpine chloride
Pilocarpinum
HSDB 3163
EINECS 202-128-4
UNII-01MI4Q9DI3
(3S,4R)-3-Ethyl-4-((1-methyl-1H-imidazol-5-yl)methyl)dihydrofuran-2(3H)-one
(3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one
01MI4Q9DI3
CHEBI:8207
DTXSID1021162
AI3-50523
CHEMBL550
(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one
(3S-cis)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone
Imidazole-5-butyric acid, alpha-ethyl-beta-(hydroxymethyl)-1-methyl-, gamma-lactone
Pilocarpine [USP:BAN:JAN]
DTXCID901162
(3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one
(3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone
(3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone
2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S,4R)-
92-13-7 (FREE BASE)
NCGC00023339-09
Pilocarpine 100 microg/mL in Acetonitrile
2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, (3S,4R)-
PILOCARPINE (MART.)
PILOCARPINE [MART.]
PILOCARPINE (USP-RS)
PILOCARPINE [USP-RS]
Pilocarpine (USP:BAN:JAN)
Pilocarpine nitrate salt
PILOCARPINE (USP MONOGRAPH)
PILOCARPINE [USP MONOGRAPH]
Pilocarpine, (+)-
CAS-92-13-7
Pilocarpine (JAN/USP)
Ocusert pilo-20 (TN)
Pilocarpina
Ocucarpine; Ocusert P 20; Ocusert Pilo
Spectrum_001107
Tocris-0694
PILOCARPINE [MI]
Prestwick0_000449
Prestwick1_000449
Prestwick2_000449
Prestwick3_000449
Spectrum2_001284
Spectrum3_000546
Spectrum4_000478
Spectrum5_001379
PILOCARPINE [JAN]
PILOCARPINE [HSDB]
PILOCARPINE [VANDF]
PILOCARPINUM [HPUS]
Lopac0_000950
Lopac0_000960
SCHEMBL15146
BSPBio_000498
BSPBio_002191
GTPL305
KBioGR_000956
KBioSS_001587
PILOCARPINE [WHO-DD]
BIDD:GT0217
DivK1c_000358
SPBio_001287
SPBio_002437
BPBio1_000548
CHEBI:39462
HY-B0726A
KBio1_000358
KBio2_001587
KBio2_004155
KBio2_006723
KBio3_001691
PILOCARPINE [ORANGE BOOK]
NINDS_000358
GLXC-20879
HMS2089K17
Tox21_110887
BDBM50008072
MFCD00153042
(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]tetrahydrofuran-2-one
AKOS016010311
Tox21_110887_1
(3S-CIS)-3-ETHYLDIHYDRO-4-
CCG-205031
DB01085
FP05587
SDCCGMLS-0003164.P005
SDCCGSBI-0050924.P006
IDI1_000358
NCGC00023339-03
NCGC00023339-06
NCGC00023339-07
NCGC00023339-08
NCGC00023339-10
NCGC00023339-11
NCGC00023339-12
NCGC00023339-13
NCGC00023339-14
NCGC00023339-16
NCGC00023339-27
NCGC00023339-28
1ST40310
BS-18966
DA-76884
NCI60_004403
SBI-0050924.P004
CS-0013746
NS00007560
C07474
D00525
E87145
AB00053525-27
AB00053525_28
AB00053525_29
EN300-19632236
Q411461
BRD-K85090592-003-18-6
BRD-K85090592-003-19-4
BRD-K85090592-008-05-2
BRD-K85090592-008-15-1
BRD-K85090592-008-22-7
SR-01000075339-11
(3S,4R)-3-Ethyl-4-(1-methyl-1H-imidazol-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one
rel-(3R,4S)-3-ethyl-4-((1-methyl-1H-imidazol-5-yl)methyl)dihydrofuran-2(3H)-one
102282-25-7
202-128-4