Skip to main content

Neostigmine Iodide

ADVERTISEMENT
Identification
Molecular formula
C27H48N2I2
CAS number
61-36-3
IUPAC name
[(3R,5S,8R,10S,13S,17R)-10,13-dimethyl-3-(trimethylammonio)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-trimethyl-ammonium;diiodide
State
State

At room temperature, neostigmine iodide is typically in a solid state, specifically as a crystalline powder. It is stable under normal conditions but should be kept in a tightly sealed container to protect it from moisture.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
637.54g/mol
Molar mass
637.5350g/mol
Density
1.3650g/cm3
Appearence

Neostigmine iodide appears as a white to off-white crystalline powder. It is typically solid at room temperature and is known for being hygroscopic, meaning it tends to absorb moisture from the air.

Comment on solubility

Solubility of [(3R,5S,8R,10S,13S,17R)-10,13-dimethyl-3-(trimethylammonio)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-trimethyl-ammonium;diiodide (C27H48N2I2)

The solubility of complex chemical compounds such as this one can be influenced by several factors. Understanding the solubility profile is crucial when considering the applications and behavior of this compound in different environments. Here are some key points to consider:

  • Polarity: Due to the presence of multiple nitrogen atoms in a quaternary ammonium structure, this compound exhibits a certain level of polarity. Quaternary ammonium compounds are often soluble in water, but the bulky hydrocarbon groups can introduce hydrophobic characteristics.
  • Ionic Character: The diiodide component implies that this compound has ionic characteristics which often enhance solubility in polar solvents, such as water or alcohol.
  • Hydration: The ability of water molecules to surround and interact with the ionic portions of the molecule can significantly affect solubility. Because of the trimethylammonio groups, hydration will likely promote solubility in polar solvents.
  • Solvent Influence: Solubility may vary with different solvents; for example, this compound might be less soluble in non-polar solvents due to its larger hydrophobic segments.

In summary, while the solubility of C27H48N2I2 is likely to be significant in polar solvents thanks to its ionic and polar components, the extent may be influenced by the size and structure of the bulky hydrocarbon substituents. Therefore, optimal solvents should be chosen based on the specific application requirements.

Interesting facts

Interesting Facts about the Compound

This fascinating compound, known as a quaternary ammonium salt, showcases a unique structural arrangement that sets it apart in the field of chemistry. Quaternary ammonium compounds have garnered significant interest due to their versatility and wide array of applications. Here are some intriguing aspects:

  • Biological Activity: Many quaternary ammonium compounds exhibit antimicrobial properties, making them valuable in pharmaceuticals and disinfectants. Their ability to disrupt cell membranes helps combat bacterial growth.
  • Structure-Activity Relationship: The compound's complex stereochemistry, indicated by its specific configuration (3R, 5S, 8R, 10S, 13S, 17R), allows researchers to investigate how different spatial arrangements influence biological interactions and pharmacological efficacy.
  • Solubilization of Drug Molecules: This compound has the potential to enhance the solubility of poorly water-soluble drugs, improving their bioavailability and therapeutic effectiveness.
  • Environmental Profile: Quaternary ammonium salts, while beneficial in various applications, can pose environmental risks. Understanding their degradability and persistence in ecosystems is crucial for ensuring their safe usage.
  • Future Research: Ongoing studies aim to explore the potential of such compounds in drug delivery systems, catalysis, and more. Their multifunctional nature opens doors to innovative solutions in multiple scientific domains.

As described by scientists, “The future of chemistry lies in our ability to manipulate compounds with precise structural features.” The compound under discussion not only exemplifies this idea but also reflects the essence of chemical innovation in developing novel materials and therapies.

In conclusion, as we delve further into the properties and applications of this remarkable compound, we inch closer to harnessing its full potential in both science and industry.

Synonyms
66-64-8
DTXSID80984475
N~3~,N~3~,N~3~,N~17~,N~17~,N~17~-Hexamethylandrostane-3,17-bis(aminium) diiodide