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Vancomycin

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Identification
Molecular formula
C66H75Cl2N9O24
CAS number
1404-90-6
IUPAC name
3,6-diamino-N-[3-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-15-yl]-4-hydroxy-hexanamide
State
State

Solid at room temperature.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.00
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.00
General information
Molecular weight
1485.72g/mol
Molar mass
1 485.7180g/mol
Density
1.3000g/cm3
Appearence

Vancomycin appears as a white or off-white solid. It is usually found in the form of a crystalline powder. It is hygroscopic, meaning it absorbs moisture from the air.

Comment on solubility

Solubility of 3,6-diamino-N-[3-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-15-yl]-4-hydroxy-hexanamide

The solubility of the compound with the formula C66H75Cl2N9O24 is an intriguing aspect to consider, particularly given its complex structure. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple hydroxymethyl groups and nitrogen atoms suggests that this compound is likely polar, which can facilitate solubility in polar solvents such as water.

  • Hydrogen Bonding: The functional groups, especially the hydroxyl and amino groups, can engage in hydrogen bonding. This enhances interactions with solvent molecules, potentially increasing solubility.

  • Hydrophobic Regions: Despite certain polar characteristics, the large hydrocarbon portions of the molecule may present hydrophobic regions that could limit solubility in aqueous environments.

  • Solvent Compatibility: The solubility would likely be greater in solvents that can sufficiently interact with both polar and non-polar regions, such as DMSO or ethanol.

In conclusion, the solubility of this compound is expected to be variable, heavily influenced by its structural features and the type of solvent employed. When considering practical applications or further experimental approaches, it is crucial to test solubility under various conditions to ascertain the most effective solvent for dissolution.

Interesting facts

Interesting Facts about 3,6-Diamino-N-[3-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentazacyclohexadec-15-yl]-4-hydroxy-hexanamide

This compound, with its complex structure, showcases the fascinating world of organic chemistry and drug design. Here are some noteworthy points:

  • Diverse Functional Groups: The compound incorporates a variety of functional groups, including amines, hydroxyls, and ureas, which contribute to its potential biological activity.
  • Polycyclic Structure: The presence of a pentazacyclohexadecane framework indicates a highly intricate molecular architecture, commonly associated with enhanced biological activities.
  • Medicinal Potential: Compounds with similar structures have been explored for their therapeutic uses, particularly as antiviral, antibacterial, or even anticancer agents due to their ability to interact with biological macromolecules.
  • Amine Groups: The 3,6-diamino moiety suggests a capacity for hydrogen bonding and potential solubility in biological contexts, making it an interesting candidate for drug formulation.
  • Structural Activity Relationship (SAR): Understanding how modifications of this compound affect its biological effectiveness could lead to the development of new pharmaceuticals, showcasing the importance of SAR studies.

As with many compounds of this complexity, studying its interactions and behaviors not only informs more about its individual properties but also enriches our understanding of molecular design and synthesis in medicinal chemistry. The intricate balance of functionality and structural integrity makes it a valuable compound for research and development.

Synonyms
33103-22-9