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3,5-Dimethyladamantan-1-amine

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Identification
Molecular formula
C12H21N
CAS number
702-89-6
IUPAC name
3,5-dimethyladamantan-1-amine
State
State

At room temperature, 3,5-Dimethyladamantan-1-amine is typically a solid.

Melting point (Celsius)
155.20
Melting point (Kelvin)
428.35
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
163.31g/mol
Molar mass
163.2740g/mol
Density
0.9575g/cm3
Appearence

3,5-Dimethyladamantan-1-amine is typically encountered as a solid, crystalline substance. Its appearance can vary based on purity, often appearing as white or off-white crystals. Its crystalline structure is notable due to the cage-like adamantane framework.

Comment on solubility

Solubility of 3,5-dimethyladamantan-1-amine (C12H21N)

The solubility of 3,5-dimethyladamantan-1-amine can be quite complex, influenced by various factors including its molecular structure and the nature of the solvent. Generally, we can consider the following points:

  • Polar vs. Non-Polar Solvents: Given that 3,5-dimethyladamantan-1-amine contains an amine functional group, it may exhibit better solubility in polar solvents such as water or ethanol. However, due to the hydrophobic adamantane structure, it may also show some degree of solubility in non-polar solvents.
  • Temperature Effects: The solubility can increase with an increase in temperature. Warmer solvents typically dissolve solutes more effectively, potentially enhancing the solubility of 3,5-dimethyladamantan-1-amine.
  • pH Levels: For amine compounds, the pH of the solution can significantly affect solubility. In more acidic conditions, the amine may become protonated, which can influence its solubility characteristics.

In practical applications, it is essential to conduct experiments to determine the precise solubility under specified conditions. As a general observation, compounds that possess similar structural traits can often show analogous solubility patterns, making it reasonable to predict:

  • Moderate solubility in aqueous solutions
  • Higher solubility in organic polar solvents

To summarize, while 3,5-dimethyladamantan-1-amine may demonstrate some solubility in various solvents, the exact solubility profile would require detailed empirical studies to elucidate its behavior in different environments.

Interesting facts

Interesting Facts about 3,5-Dimethyladamantan-1-amine

3,5-Dimethyladamantan-1-amine is a fascinating compound that has captured the interest of chemists and researchers alike. Its unique structure and properties lend it a special place in the world of organic chemistry.

Structural Insights

This compound belongs to the adamantane family, which is known for its cage-like structure. Here are some notable characteristics:

  • Structure: The adamantane core provides rigidity and stability, making it an interesting subject for study.
  • Substituents: The presence of two methyl groups at the 3 and 5 positions enhances the compound's steric properties, potentially affecting its reactivity and interactions.

Applications and Importance

While some compounds are known for specific industrial uses, 3,5-dimethyladamantan-1-amine is particularly noted for its potential in medicinal chemistry. Here are some applications:

  • Pharmacological Interest: There is ongoing research into its potential as a drug, particularly in developing new therapeutic agents.
  • Research Tool: Its structure and properties make it useful for understanding the behavior of similar compounds and their interactions.

Chemical Behavior

The reactivity of 3,5-dimethyladamantan-1-amine can differ significantly from other amines due to its bulky structure:

  • Amine Properties: As an amine, it can act as a nucleophile in various chemical reactions.
  • Hydrogen Bonding: It has the potential to form hydrogen bonds, influencing its solubility and interaction with other molecules.

In summary, 3,5-dimethyladamantan-1-amine exemplifies the beauty and complexity of organic molecules. Its distinctive structure and potential applications continue to inspire research and innovation in chemistry. As the famous chemist Linus Pauling once said, "Chemistry is the science of the properties, composition, and structure of matter." This compound certainly embodies those principles!

Synonyms
memantine
19982-08-2
3,5-dimethyladamantan-1-amine
1-Amino-3,5-dimethyladamantane
Memantina
3,5-Dimethyl-1-adamantanamine
1,3-Dimethyl-5-adamantanamine
alzantin
Memantinum
3,5-Dimethyl-1-aminoadamantane
Memantine [INN]
Memantinum [INN-Latin]
Memantina [INN-Spanish]
nemdatine
3,5-Dimethyl-1-adamantylamine
Tricyclo[3.3.1.13,7]decan-1-amine, 3,5-dimethyl-
HSDB 7327
UNII-W8O17SJF3T
DRG-0267
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
W8O17SJF3T
1,3-Dimethyl-5-aminoadamantane
DTXSID5045174
CHEBI:64312
D-145
DRG 0267
CHEMBL807
NSC-757843
DMAA [Antiparkinson Agent]
DTXCID3025174
Memantine (INN)
Tricyclo(3.3.1.13,7)decan-1-amine, 3,5-dimethyl-
NSC 757843
Tricyclo(3.3.1.1(3,7))decan-1-amine, 3,5-dimethyl-
NCGC00015705-04
Memantin
Memantinum (INN-Latin)
Memantina (INN-Spanish)
DMAA (Antiparkinson Agent)
D 145
Memantine [INN:BAN]
3,5-DIMETHYLTRICYCLO(3.3.1.1(SUP 3,7))DECAN-1-AMINE
TRICYCLO(3.3.1.1(SUP 3,7))DECAN-1-AMINE, 3,5-DIMETHYL-
N06DX01
CAS-19982-08-2
3,5-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
3,5-dimethyladamantanylamine
Exiba
Exiba (TN)
Spectrum_000607
3,5-Dimethyltricyclo-
MEMANTINE [MI]
MEMANTINE [HSDB]
Prestwick0_000978
Prestwick1_000978
Prestwick2_000978
Prestwick3_000978
Spectrum2_001408
Spectrum3_000923
Spectrum4_001022
Spectrum5_001355
MEMANTINE [VANDF]
CBMicro_020348
Biomol-NT_000209
MEMANTINE [WHO-DD]
SCHEMBL2688
Lopac0_000861
Oprea1_480562
BSPBio_001015
KBioGR_001543
KBioSS_001087
DivK1c_000068
SPBio_001456
SPBio_002926
1-amino-3,5-dimethyladamantan
BPBio1_001117
BPBio1_001270
GTPL4253
SCHEMBL13213676
HMS500D10
KBio1_000068
KBio2_001087
KBio2_003655
KBio2_006223
KBio3_001926
1-amino-3,5-dimethyl adamantane
1-amino-3,5-dimethyl-adamantane
NINDS_000068
3,5-Dimethyl-adamantan-1-ylamine
ALBB-013872
BCP29702
Tox21_110199
3,5-Dimethyl-1-aminoadamantane HCl
BBL000737
BDBM50062599
STK520682
AKOS000113995
AKOS015953276
AKOS016340748
Tox21_110199_1
CCG-204092
DB01043
DS-3152
SDCCGSBI-0020417.P005
IDI1_000068
NCGC00015705-03
NCGC00015705-05
NCGC00015705-07
NCGC00015705-09
NCGC00015705-16
NCGC00024782-02
NCGC00024782-03
D145 pound>>D 145 pound>>D-145
FM153268
SBI-0020417.P004
AB00053600
EU-0053634
NS00000622
D08174
D94592
EN300-103626
AB00053600-13
AB00053600_14
AB00053600_15
Q412189
BRD-A79803969-003-16-1
BRD-A79803969-003-17-9
BRD-A79803969-003-18-7