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3,5-Dimethylpyrazole

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Identification
Molecular formula
C5H8N2
CAS number
67-51-6
IUPAC name
3,5-dimethyl-1H-pyrazole
State
State

At room temperature, 3,5-Dimethylpyrazole is typically in a solid state.

Melting point (Celsius)
107.00
Melting point (Kelvin)
380.15
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
96.14g/mol
Molar mass
96.1410g/mol
Density
1.0830g/cm3
Appearence

3,5-Dimethylpyrazole appears as white crystalline solid. It may also appear as a colorless crystalline powder with a characteristic odor.

Comment on solubility

Solubility of 3,5-Dimethyl-1H-pyrazole (C5H8N2)

3,5-Dimethyl-1H-pyrazole is an intriguing compound with distinct solubility characteristics. Generally, the solubility of organic compounds like this pyrazole derivative is influenced by several factors:

  • Polarity: The presence of nitrogen atoms contributes to some polarity, which can enhance solubility in polar solvents such as water.
  • Hydrophobic groups: The presence of multiple methyl groups makes it somewhat hydrophobic, thereby limiting its solubility in water, but enhancing solubility in organic solvents.
  • Temperature: Higher temperatures may increase solubility due to greater kinetic energy allowing for better interactions.

In summary, while 3,5-dimethyl-1H-pyrazole has a good solubility in organic solvents such as ethanol and acetone, its solubility in water is relatively limited due to its structure. To better understand its solubility, researchers often conduct experiments measuring solubility under various conditions, noting that:

  1. The compound exhibits moderate solubility in polar organic solvents.
  2. Solubility is less favorable in pure water.
  3. Functional group interactions play a significant role in solubility behavior.

Therefore, while 3,5-dimethyl-1H-pyrazole does not dissolve readily in water, it demonstrates favorable solubility in many organic solvents, making it versatile for various applications.

Interesting facts

Interesting Facts about 3,5-Dimethyl-1H-Pyrazole

3,5-Dimethyl-1H-pyrazole is a fascinating organic compound that belongs to the class of pyrazoles, which are five-membered heterocyclic compounds containing two adjacent nitrogen atoms. This compound has garnered substantial attention in the fields of pharmaceuticals and agrochemicals, due to its diverse biological activities.

Biological Significance

This compound is known for its potential pharmacological properties, which include:

  • Anti-inflammatory effects - It exhibits properties that may help reduce inflammation in various biological systems.
  • Anti-cancer activity - Some studies suggest that it may inhibit the growth of certain cancer cell lines.
  • Antiviral properties - It has been evaluated for efficacy against viral infections.

Applications

3,5-Dimethyl-1H-pyrazole also finds numerous applications in other sectors:

  • As a Building Block: It serves as a crucial intermediate in synthesizing various pharmaceutical agents.
  • In Agrochemicals: It can be employed in the development of herbicides and fungicides, due to its ability to modify biological responses in plants.

Chemical Properties

From a synthetical viewpoint, 3,5-dimethyl-1H-pyrazole displays interesting reactivity patterns, which can be exploited in chemical transformations, making it an attractive target for synthetic chemists. As noted by chemists, "the versatility of nitrogen-containing compounds like pyrazoles opens doors to innovative research and applications."

Conclusion

In conclusion, 3,5-dimethyl-1H-pyrazole is not only of academic interest but also plays a significant role in practical applications, ranging from drug development to agricultural chemistry, making it a noteworthy compound in contemporary chemical research.

Synonyms
3,5-Dimethylpyrazole
3,5-Dimethyl-1H-pyrazole
67-51-6
1H-Pyrazole, 3,5-dimethyl-
PYRAZOLE, 3,5-DIMETHYL-
3,5 DMP
3,5-Dwumetylopirazolu
TH 564
NSC 8729
U 6245
3,5-Dwumetylopirazolu [Polish]
EINECS 200-657-5
MFCD00005243
UNII-H21N865K9J
BRN 0106325
H21N865K9J
NSC-8729
TRIXENE DP 8692
1(H)-3,5-Dimethylpyrazole
DTXSID5058777
SDXAWLJRERMRKF-UHFFFAOYSA-
EC 200-657-5
5-23-05-00110 (Beilstein Handbook Reference)
TH-564
U-6245
3,5-dimethyl pyrazole
dimethylpyrazole
3,5Dwumetylopirazolu
Pyrazole,5-dimethyl-
3,5Dimethyl1Hpyrazole
Pyrazole, 3,5dimethyl
3,5-Dimethyl-Pyrazole
1H-Pyrazole,5-dimethyl-
1HPyrazole, 3,5dimethyl
3,5-dimethyl-1H-pyrazol
3,5-Dimethylpyrazole, 99%
QSPL 007
CHEMBL1828957
DTXCID1044853
NSC8729
CHEBI:229331
BCP32182
STK299969
AKOS000120332
AS-5542
FD45132
SB16017
NCGC00342010-01
SY001302
DB-304254
D1647
NS00007733
EN300-16235
P19711
AB00374449-03
AC-907/34116050
AE-848/32586026
Q17122069
Z50145988
3,5-Dimethyl-1H-pyrazole;1H-Pyrazole, 3,5-dimethyl-
F1982-0002
3,5-Dimethylpyrazole, produced by Wacker Chemie AG, Burghausen, Germany, >=99.0% (GC)
200-657-5