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(3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone

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Identification
Molecular formula
C17H12Br2O3
CAS number
22905-67-7
IUPAC name
(3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone
State
State

At room temperature, the compound is in a solid state, typically found as a crystalline powder. It is stable under standard conditions of storage and handling.

Melting point (Celsius)
145.50
Melting point (Kelvin)
418.65
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.95
General information
Molecular weight
423.09g/mol
Molar mass
424.0330g/mol
Density
1.6700g/cm3
Appearence

The compound is typically a solid at room temperature. Its crystalline form is characterized by its off-white color.

Comment on solubility

Solubility of (3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone

The compound (3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone with the chemical formula C17H12Br2O3 exhibits unique solubility characteristics that can be influenced by its functional groups and molecular structure.

Solubility in Common Solvents

  • Organic Solvents: This compound is expected to have good solubility in organic solvents such as ethanol, DMSO (Dimethyl sulfoxide), and acetone due to its hydrophobic aromatic regions.
  • Aqueous Solutions: The presence of the hydroxy group (-OH) may enhance its solubility in water to some extent; however, the overall solubility in aqueous environments may be limited because of the bulky brominated aromatic components.

Factors Affecting Solubility

Several key factors can significantly influence the solubility of this compound:

  • Molecular Weight: With a molecular weight approaching 400 g/mol, larger compounds often exhibit decreased solubility compared to smaller molecules.
  • Hydrophilicity vs. Hydrophobicity: The presence of both the bromine atoms, which increase hydrophobicity, and the hydroxy group, which contributes hydrophilicity, creates a competition that can impact overall solubility.
  • Temperature: As temperature increases, typically, solubility increases. Testing solubility at elevated temperatures may yield different results.

In summary, the solubility of (3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone is a fascinating interplay of its molecular structure and functional groups. Understanding these characteristics is crucial for its applications in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about (3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone

(3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone is a fascinating chemical compound that showcases the intricate relationships between structure and function in organic chemistry. Here are some intriguing aspects of this compound:

  • Complex Structure: The compound consists of multiple functional groups, including a benzofuran moiety and a hydroxyl group. This complex structure contributes to its unique chemical properties and potential applications.
  • Potential Biological Activity: Compounds with bromine substitutions, like this one, often exhibit interesting biological activities. Brominated compounds are known for their potential as pharmaceuticals, which could target various biological pathways.
  • Functionalization: The presence of the hydroxy group suggests that this compound may have enhanced reactivity, making it a candidate for further chemical modification in synthetic chemistry.
  • Applications: Compounds of this type may find applications in fields such as medicinal chemistry and materials science. For instance, they can be studied for use as anti-cancer agents or in the development of new materials with specific properties.
  • Environmental Considerations: The presence of bromine in organic compounds can lead to concerns about environmental persistence and toxicity. It is essential for scientists to evaluate the environmental impact of such compounds in development and application.

As a chemistry student exploring the depths of organic compounds, one can appreciate the intricate balance between structure and function. With compounds like (3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone, there lies excitement in unraveling their potential while being mindful of their environmental implications. This multifaceted compound serves as an excellent example of the ongoing exploration in the field of chemical sciences.

Synonyms
benzbromarone
3562-84-3
Benzbromaron
Desuric
Urinorm
Minuric
Normurat
Uricovac
Exurate
Hipurik
Azubromaron
Narcaricin
L 2214-Labaz
Harolan
Uroleap (TN)
MJ 10061
Benzbromaronum
Benzobromarona
Uroleap
Methanone, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-
3,5-Dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone
Benzpromarone
Benzbromaronum [INN-Latin]
2-Ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran
Benzobromarona [INN-Spanish]
L 2214
L-2214
L2214-Labaz
NSC 85433
Benzbromarone [USAN:INN:BAN]
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
NSC-85433
L2214
3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran
Benzbromarona
KETONE, 3,5-DIBROMO-4-HYDROXYPHENYL 2-ETHYL-3-BENZOFURANYL
(3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone
NSC85433
EINECS 222-630-7
4POG0RL69O
MFCD00078962
BRN 0273668
CHEBI:3023
DTXSID4022652
Benzofuran, 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-
(2-Ethyl-3-benzofuranyl)-(3,5-dibrom-4-hydroxyphenyl)keton
BENZBROMARONE [MI]
BENZBROMARONE [INN]
BENZBROMARONE [JAN]
(3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
BENZBROMARONE [USAN]
CPD000058310
MJ-10061
BENZBROMARONE [MART.]
BENZBROMARONE [WHO-DD]
MLS000028522
MLS000737128
CHEMBL388590
DTXCID702652
Besuric
BENZBROMARONE [EP MONOGRAPH]
NCGC00013895-08
3, 5-Dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone
3-[3,5-DIBROMO-4-HYDROXYBENZOYL]-2-ETHYLBENZOFURAN
SMR000058310
CAS-3562-84-3
Benzbromaronum (INN-Latin)
Benzobromarona (INN-Spanish)
BENZBROMARONE (MART.)
2,6-dibromo-4-[(2-ethyl-1-benzofuran-3-yl)carbonyl]phenol
3,5-dibromo-4-hydroxyphenyl 2-ethylbenzo[b]furan-3-yl ketone
BENZBROMARONE (EP MONOGRAPH)
Max-uric
[3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone
SR-01000003082
UNII-4POG0RL69O
2,6-dibromo-4-((2-ethyl-1-benzofuran-3-yl)carbonyl)phenol
3,5-Dibromo-4-hydroxyphenyl 2-ethylbenzo(b)furan-3-yl ketone
benzbromaron?
Narcaricin mite
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone
ML054
Benzbromarone,(S)
NCI85433
R75
Prestwick_709
Benzbromarone(USAN)
3,5-Dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl Ketone
Benzbromarone (Standard)
Opera_ID_1282
Prestwick0_000370
Prestwick1_000370
Prestwick2_000370
Prestwick3_000370
Benzbromarone 100 microg/mL in Acetonitrile
cid_2333
NCIStruc1_001498
NCIStruc2_001681
Oprea1_140235
SCHEMBL48993
BSPBio_000499
MLS001074105
MLS001424143
2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran
SPBio_002420
BPBio1_000549
HY-B1135R
M04AB03
Benzbromarone, analytical standard
Benzbromarone (JP18/USAN/INN)
HMS1569I21
HMS2052K05
HMS2093J04
HMS2096I21
HMS2230D20
HMS3394K05
HMS3652H15
HMS3713I21
HMS3744G15
Pharmakon1600-01505971
(3,5-Dibromo-4-hydroxyphenyl)-(2-ethylbenzofuran-3-yl)methanone
BCP07515
EX-A1131
HY-B1135
Tox21_110041
(3,5-dibromo-4-hydroxy-phenyl)-(2-ethylbenzofuran-3-yl)methanone
BDBM50158460
CCG-37198
NCGC00013895
NSC759281
s4221
Benzbromarone 1.0 mg/ml in Methanol
AKOS015895856
Tox21_110041_1
AC-6162
CS-4740
DB12319
FD18180
KS-1292
NC00334
NSC-759281
NCGC00013895-01
NCGC00013895-02
NCGC00013895-03
NCGC00013895-04
NCGC00013895-05
NCGC00013895-06
NCGC00013895-07
NCGC00013895-09
NCGC00013895-11
NCGC00013895-13
NCGC00022066-04
NCI60_041884
SY018127
SBI-0055383.P002
B4099
NS00001815
SW196858-4
UNM000001228903
D01056
Q410435
SR-01000003082-5
SR-01000003082-6
BRD-K11717138-001-03-0
BRD-K11717138-001-16-2
BRD-K11717138-001-29-5
BRD-K11717138-001-30-3
Ketone,5-dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl
Benzbromarone, certified reference material, TraceCERT(R)
Benzbromarone, European Pharmacopoeia (EP) Reference Standard
Methanone,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-
(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone #
Methanone, (3, 5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-
222-630-7
benzbromarone; bzm; 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran; (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
Benzbromarone;3,5-Dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl ketone;2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran