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Pyrazinamide derivative

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Identification
Molecular formula
C13H10Cl3N5O
CAS number
423228-05-2
IUPAC name
3,5-diamino-6-chloro-N-[1-[(2,4-dichlorophenyl)methylamino]vinyl]pyrazine-2-carboxamide
State
State

At room temperature, this compound is in a solid state, typically appearing as crystalline powder.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.15
Boiling point (Celsius)
276.80
Boiling point (Kelvin)
549.95
General information
Molecular weight
402.60g/mol
Molar mass
402.6040g/mol
Density
1.4760g/cm3
Appearence

3,5-diamino-6-chloro-N-[1-[(2,4-dichlorophenyl)methylamino]vinyl]pyrazine-2-carboxamide is typically a crystalline solid with light yellow to beige coloration, often used as an intermediate in chemical synthesis.

Comment on solubility

Solubility Characteristics

The compound 3,5-diamino-6-chloro-N-[1-[(2,4-dichlorophenyl)methylamino]vinyl]pyrazine-2-carboxamide (C13H10Cl3N5O) exhibits interesting solubility properties worthy of exploration. Generally, the solubility of organic compounds like this one can be influenced by various factors, including:

  • Molecular Structure: The presence of multiple functional groups, such as amines and carboxamides, can enhance solubility in polar solvents due to hydrogen bonding.
  • Chlorine Atoms: The chlorinated phenyl group may affect the overall polarity, potentially decreasing solubility in organic solvents while increasing it in aqueous environments.
  • Impurity Considerations: The purification process can significantly impact solubility assessments, as impurities may alter solubility behavior.

In terms of polar solvents, this compound is expected to be more soluble due to its polar character stemming from functional groups. As stated, “the more polar the solvent, the higher the potential solubility for polar compounds.” However, dissolution can vary by characteristics such as:

  1. Temperature: Increased temperature often enhances solubility.
  2. pH Levels: Since ionic forms of compounds may form under varying pH, the solubility could change in different pH environments.

In summary, the solubility of C13H10Cl3N5O is likely to be influenced by its molecular structure and the nature of the solvents used. Further empirical data is needed to provide a definitive profile of its solubility under varying conditions.

Interesting facts

Interesting Facts about 3,5-Diamino-6-chloro-N-[1-[(2,4-dichlorophenyl)methylamino]vinyl]pyrazine-2-carboxamide

This intriguing compound belongs to a class of pyrazine derivatives, which are known for their diverse biological activities. Here are some interesting aspects of this compound:

  • Pharmaceutical Potential: Due to its complex structure, this compound has been studied for its potential use in pharmaceuticals, particularly in the treatment of various diseases. Its ability to interact with biological targets makes it a candidate for drug development.
  • Chloro-Substituents: The presence of multiple chlorine atoms in its structure not only influences the compound's reactivity but also enhances its biological activity, often impacting its pharmacokinetic properties.
  • Diverse Applications: Beyond medicinal uses, compounds similar to this one are often explored in agricultural chemistry as **pesticides** or **fungicides**, providing insights into their potential role in enhancing crop yields.
  • Multi-Target Interaction: One of the fascinating aspects of this compound is its ability to interact with multiple biological pathways, which is particularly vital in drug design where targeting multiple mechanisms may provide therapeutic advantages.
  • Research Interest: Researchers are constantly interested in modifications of pyrazine derivatives because slight changes in their chemical structure can yield significantly different biological activities. This compound serves as an excellent example of this principle in action.

In summary, the compound 3,5-diamino-6-chloro-N-[1-[(2,4-dichlorophenyl)methylamino]vinyl]pyrazine-2-carboxamide showcases the intricate relationship between chemical structure and biological function, making it a subject of ongoing research and interest in the fields of medicinal and agricultural chemistry. Its unique properties help scientists continue to unravel the complex mechanisms at play in various biological systems.

Synonyms
Bio1_000038
CBiol_001752
SCHEMBL8259781
Bio1_000527
Bio1_001016