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D-Glucose 6-phosphate

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Identification
Molecular formula
C6H13O9P
CAS number
56-73-5
IUPAC name
[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate
State
State

At room temperature, D-glucose 6-phosphate is in a solid state. It is typically stored in a dry form to maintain its stability.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
260.14g/mol
Molar mass
260.1360g/mol
Density
1.5400g/cm3
Appearence

D-glucose 6-phosphate typically appears as a white or off-white crystalline powder. It is often supplied as a sodium or potassium salt, which also appear as solid powders.

Comment on solubility

Solubility of [3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate

The solubility of the compound [3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate (C6H13O9P) is of interest due to its practical applications in various fields, particularly in biochemistry and pharmaceuticals. Here are some key points to consider regarding its solubility:

  • Polarity: The presence of multiple hydroxyl groups contributes to significant polarity, which typically enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules likely aids in its dissolution process.
  • pH Dependence: As a phosphate compound, solubility may increase in more basic or acidic environments due to alterations in ionic forms.
  • Complex Formation: It may form soluble complexes with cations, further influencing its solubility profile.

In general, compounds like this with many hydrophilic (water-attracting) functional groups tend to exhibit a high degree of solubility in aqueous solutions, making them versatile in various chemical applications.


Interesting facts

Interesting Facts About [3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate

This compound, often referred to as a derivative of a cyclic sugar alcohol, holds a myriad of intriguing features that chemists and biochemists find particularly captivating. It is essential in the discussion of biochemical processes and molecular structures due to its unique configuration and functional group presence. Below are some fascinating aspects:

  • Structural Significance: The compound showcases a tetrahydropyran ring, which contributes to its stability and reactivity, making it an interesting subject for studying carbohydrate chemistry.
  • Functional Groups: The presence of multiple hydroxy groups (trihydroxy) indicates that this compound is likely to engage in hydrogen bonding, enhancing its solubility in water and interactions with biomolecules.
  • Biochemical Relevance: Compounds like this one often serve as important intermediates in metabolic pathways, particularly in the synthesis of nucleotides or as potential signaling molecules.
  • Applications in Research: Due to its phosphate group, this compound can be explored for its role in energy transfer and storage in biochemical systems, comparable to ATP.
  • Potential Therapeutic Uses: Investigation into derivatives and analogs of this structure may reveal therapeutic agents, particularly in fields like drug design and development, where modifications can align with specific biological targets.

In summary, while [3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] dihydrogen phosphate may seem complex at first glance, its potential applications and structural characteristics make it a fascinating subject for research. The intricate dance between its functional groups opens doors to a deeper understanding of biochemical functions and interactions.

Synonyms
1-O-phosphonohexopyranose
Hexose 1-phosphate
NSC44138
6799-01-5
NSC-44138
210100-25-7
hexose 1-phosphates
L-galactose-1-phosphate
?-D-Mannose 1-phosphate
a-d-galactose-1-phosphate
GLUCOSE-L-PHOSPHATE
SCHEMBL721178
glucose-1-(dihydrogenphosphate)
SCHEMBL24021536
CHEBI:24588
DTXSID20861599
(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl dihydrogen phosphate
QAA97807
MG30721
[(3s,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphosphonic acid
63779-58-8
NCI60_004022
NS00015212
NS00078964
C01002
FA7B7606-D8E0-42AD-BE0E-7660D1DD395D
[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphosphonic acid