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Glucose-6-phosphate

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Identification
Molecular formula
C6H13O9P
CAS number
56-73-5
IUPAC name
[3,4,5-trihydroxy-6-[4,5,6-trihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-tetrahydropyran-2-yl]methyl dihydrogen phosphate
State
State

At room temperature, glucose-6-phosphate is typically in a solid state when dry, appearing as a white to off-white crystalline powder. It is hygroscopic and dissolves readily in water, where it exists in equilibrium with its aqueous solution form.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
260.14g/mol
Molar mass
260.1360g/mol
Density
1.6000g/cm3
Appearence

Glucose-6-phosphate typically appears as a white crystalline powder. It is very soluble in water.

Comment on solubility

Solubility of 3,4,5-Trihydroxy-6-[4,5,6-trihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-tetrahydropyran-2-yl]methyl dihydrogen phosphate (C6H13O9P)

This compound exhibits interesting solubility characteristics typical of phosphates and sugar-like structures. Understanding its solubility can be crucial for various applications, particularly in biochemical contexts. Here are some key points to consider regarding its solubility:

  • Water Solubility: Due to the presence of multiple hydroxyl groups (–OH), this compound is expected to be soluble in water. The hydroxyl groups can form hydrogen bonds with water molecules, enhancing solubility.
  • Influence of pH: The solubility can be influenced by the pH of the solution. At lower pH levels, protonation may occur, potentially increasing solubility in acidic environments.
  • Salt Formation: The dihydrogen phosphate group can lead to increased solubility when interacting with cations, creating more soluble phosphate salts.
  • Organic Solvents: Its solubility in organic solvents is likely to be low due to the polar nature of the compound; hence, it prefers aqueous environments.

In summary, the solubility of C6H13O9P is primarily governed by hydrogen bonding and the influence of pH. For applications in solution, it is essential to consider these properties to maximize effectiveness and ensure stability.

Interesting facts

Interesting Facts about 3,4,5-Trihydroxy-6-[4,5,6-trihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-tetrahydropyran-2-yl]methyl dihydrogen phosphate

This compound is a fascinating molecule with a complex structure and significant biochemical relevance. Below are some interesting facts about this intriguing chemical:

  • Biochemical Significance: This compound contains phosphate, which plays a crucial role in energy transfer through ATP, DNA, and RNA. Its incorporation of multiple hydroxy groups can affect its reactivity and interactions in biological systems.
  • Structural Insight: The presence of multiple tetrahydropyran rings is notable. These cyclic structures can help in mimicking certain biological molecules, potentially leading to interesting applications in drug design.
  • Sugar and Phosphate Link: The combination of sugar-like structures with phosphate groups makes this compound relevant in the study of nucleotides and other phosphate-containing biomolecules.
  • Potential Applications: Given its structure, this compound could be explored for various applications in medicinal chemistry, particularly in synthesizing analogs to target specific enzymes or receptors.
  • Research Interests: This molecule's unique properties invite further research, especially in understanding how sugar-phosphate conjugates can influence cellular pathways and metabolism.

In summary, the complex interplay between its hydroxy and phosphate groups may unveil new therapeutic pathways and challenge our understanding of carbohydrate biology. As the field of medicinal chemistry advances, compounds like this one will continue to play an essential role in innovative research.

Synonyms
[3,4,5-trihydroxy-6-[4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-2-yl]methyl dihydrogen phosphate
(3,4,5-trihydroxy-6-(4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl)oxyoxan-2-yl)methyl dihydrogen phosphate
Hex6P(?1-4)Hex
G46069TG