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Nicotine-1-N-oxide glucuronide

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Identification
Molecular formula
C16H21N3O9
CAS number
130874-17-6
IUPAC name
3,4,5-trihydroxy-6-[1-methyl-2-oxo-5-(3-pyridyl)pyrrolidin-3-yl]oxy-tetrahydropyran-2-carboxylic acid
State
State

At room temperature, Nicotine-1-N-oxide glucuronide is typically a solid. As with many glucuronic acid conjugates, it can form crystalline structures and is generally handled in solid form for chemical applications.

Melting point (Celsius)
239.00
Melting point (Kelvin)
512.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
374.37g/mol
Molar mass
374.3740g/mol
Density
1.3000g/cm3
Appearence

This compound appears as a crystalline solid. The exact form, such as powder or crystals, can depend on the specific processing and purity of the sample. It usually does not have color or can be slightly colored, and the texture can vary from amorphous to slightly granular depending on its hydrated state and handling.

Comment on solubility

Solubility of 3,4,5-trihydroxy-6-[1-methyl-2-oxo-5-(3-pyridyl)pyrrolidin-3-yl]oxy-tetrahydropyran-2-carboxylic acid

The solubility of a compound is a crucial aspect that influences its application in various fields, including pharmaceuticals and chemistry. For the compound 3,4,5-trihydroxy-6-[1-methyl-2-oxo-5-(3-pyridyl)pyrrolidin-3-yl]oxy-tetrahydropyran-2-carboxylic acid (C16H21N3O9), the presence of multiple functional groups suggests some unique solubility characteristics. Key points about its solubility include:

  • Hydrophilicity: The hydroxyl (-OH) groups contribute to high hydrophilicity, making the compound more soluble in water.
  • Polar Nature: The polar character due to the carboxylic acid and pyridine moieties can enhance interactions with polar solvents.
  • Solvent Dependence: The solubility may vary significantly in different solvents, indicating that while it may dissolve readily in water, its behavior in organic solvents could be diverse.
  • Potential Formulations: Given its solubility profile, it could be ideal for specific formulations, particularly in drug delivery systems.

In summary, the solubility of this compound appears to be favorably influenced by its functional groups. Understanding the nuances of solubility is essential, as it can greatly impact the compound's behavior in various environments and applications.

Interesting facts

Interesting Facts about 3,4,5-Trihydroxy-6-[1-methyl-2-oxo-5-(3-pyridyl)pyrrolidin-3-yl]oxy-tetrahydropyran-2-carboxylic Acid

This intriguing compound belongs to the class of functionalized polyols and exhibits a unique structure that combines both hydrophilic and lipophilic characteristics. Here are some compelling points about this compound:

  • Structural Complexity: The molecule is built around a tetrahydropyran framework, which is highly versatile in organic synthesis. Its multi-hydroxy substitutions enable a vast array of potential chemical reactions.
  • Biological Relevance: Compounds similar in structure to this molecule are often investigated for their biological activities, including antiviral and antibacterial properties. The presence of the pyridine moiety is particularly noteworthy, as it commonly contributes to biological activity.
  • Application Potential: Researchers are exploring compounds like this for their potential use in pharmaceutical applications, especially in drug design and development, where novel bioactive molecules are sought.
  • Hydroxyl Groups: With three hydroxyl (-OH) groups present, this compound has the potential for extensive hydrogen-bonding interactions, which may influence its solubility, biological activity, and structural properties.
  • Chirality and Isomerism: The compound can exhibit chirality due to the presence of asymmetric carbon centers. Studying its stereoisomers could reveal different pharmacokinetic profiles and biological activities.

“In the world of chemistry, complexity breeds innovation.” This quote encapsulates the essence of compounds like 3,4,5-trihydroxy-6-[1-methyl-2-oxo-5-(3-pyridyl)pyrrolidin-3-yl]oxy-tetrahydropyran-2-carboxylic acid, igniting curiosity for further exploration and research.

Overall, the richness of this compound’s structure not only reflects its potential in diverse applications but also serves as a testament to the endless possibilities found in medicinal chemistry.

Synonyms
N-(trans-3-Hydroxycotinine)-b-D-glucuronide
Trans-3'-Hydroxycotinine O glucoronide
NS00115022