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5-phosphoribosyl-1-pyrophosphate

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Identification
Molecular formula
C5H13O14P3
CAS number
97-55-2
IUPAC name
[3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate
State
State

This compound is usually found as a solid at room temperature.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.00
Boiling point (Celsius)
100.00
Boiling point (Kelvin)
373.00
General information
Molecular weight
330.14g/mol
Molar mass
330.1360g/mol
Density
2.1000g/cm3
Appearence

The compound is generally a white powdered solid, typical of many phosphate-based molecules which often lack color.

Comment on solubility

Solubility of [3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate

The solubility of [3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate (C5H13O14P3) is influenced by several factors, notably its complex molecular structure and functional groups. Understanding its solubility characteristics is crucial for applications in various chemical processes and formulations.

Key solubility insights:

  • Polarity: The presence of multiple hydroxyl (-OH) groups contributes to the overall polarity of the molecule, enhancing its ability to interact with polar solvents such as water.
  • Hydrogen bonding: The hydroxyl and phosphono functional groups enable extensive hydrogen bonding, which can significantly increase solubility in aqueous environments.
  • pH dependence: Solubility may be affected by the pH of the solution; ionization can occur under various pH conditions, altering how the compound interacts with solvent molecules.
  • Concentration factors: At higher concentrations, solubility may limit due to saturation effects, leading to precipitation or decreased solvation efficiency.

In summary, while [3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate shows tendencies toward good solubility in polar solvents, specific conditions must be considered for optimal performance. As with many phosphonate compounds, it can exhibit solubility variability based on the surrounding chemical environment.

Interesting facts

Interesting Facts about [3,4-Dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl] Dihydrogen Phosphate

[3,4-Dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate is a fascinating compound that finds its significance in various scientific realms, particularly in biochemistry and medicinal chemistry.

Biological Relevance

This compound plays a crucial role as a *phosphate donor*, which is essential in numerous biological processes. Its involvement can be highlighted through the following key points:

  • Energy Transfer: Phosphate groups are pivotal for energy transfer in biological systems, particularly in ATP (adenosine triphosphate) metabolism.
  • Signal Transduction: Phosphorylation is a common mechanism in cell signaling pathways, impacting protein interactions and functions.
  • Metabolic Pathways: Compounds such as this one could be involved in various metabolic pathways, highlighting their importance in cellular function.

Synthetic Utility

The synthesis of [3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate is of particular interest to chemists due to its relatively unique structure:

  • Functionalization: It showcases how modifications at specific carbon centers can lead to diverse functionalities.
  • Precursors: This compound can serve as a precursor in the synthesis of more complex molecules, enhancing the toolkit available to synthetic chemists.

Application in Research

Due to its phosphono- and hydroxy-functional groups, researchers are exploring this compound for its potential in:

  • Drug Development: Investigating its structure-activity relationship (SAR) helps in the design of new therapeutic agents.
  • Biochemical Studies: Acts as a model compound to study phosphate interactions in enzymes and biochemical reactions.

In summary, [3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl] dihydrogen phosphate embodies a remarkable intersection of chemistry, biology, and medicine, making it a subject of interest for scientists looking to understand and manipulate biochemical processes.

Synonyms
14689-84-0