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Proline

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Identification
Molecular formula
C5H9NO2
CAS number
147-85-3
IUPAC name
3,4-dihydro-2H-pyrrole-2-carboxylic acid
State
State
Proline is typically found in a solid state at room temperature. It is hygroscopic, meaning it can absorb moisture from the air.
Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
234.00
Boiling point (Kelvin)
507.15
General information
Molecular weight
115.13g/mol
Molar mass
115.1300g/mol
Density
1.3500g/cm3
Appearence

Proline appears as a white crystalline powder. It is one of the twenty amino acids used in living organisms as the building blocks of proteins. It is unique due to its cyclic structure, which plays a significant role in the structure of proteins.

Comment on solubility

Solubility of 3,4-dihydro-2H-pyrrole-2-carboxylic acid

3,4-dihydro-2H-pyrrole-2-carboxylic acid, with the chemical formula C5H9NO2, is a fascinating compound with notable solubility characteristics.

Solubility Insights

This compound exhibits a range of solubilities in various solvents:

  • Water: Generally, carboxylic acids like this one can exhibit good solubility in water due to their ability to form hydrogen bonds.
  • Polar solvents: The presence of both an amine and a carboxylic acid functional group enhances its solubility in polar solvents, making it compatible with substances like ethanol and methanol.
  • Non-polar solvents: On the other hand, 3,4-dihydro-2H-pyrrole-2-carboxylic acid is likely to be poorly soluble in non-polar solvents due to its polar functional groups.

Moreover, the solubility can be affected by factors such as temperature and pH. As temperature increases, the solubility in water tends to rise, which is a common trend observed with many organic compounds.

In summary, 3,4-dihydro-2H-pyrrole-2-carboxylic acid demonstrates versatile solubility properties, making it valuable for various applications in chemistry. Understanding its solubility patterns is crucial for utilizing this compound effectively in synthesis and formulation processes.

Interesting facts

Interesting Facts about 3,4-dihydro-2H-pyrrole-2-carboxylic Acid

3,4-dihydro-2H-pyrrole-2-carboxylic acid, often simply referred to as a pyrrole derivative, is a fascinating compound in the realm of organic chemistry. This compound is characterized by several noteworthy attributes:

  • Structural Significance: The pyrrole ring is a five-membered aromatic ring that plays a crucial role in numerous biological systems. Its structure allows for interesting reactivity and interactions with other molecules.
  • Biological Relevance: Pyrrole derivatives, including 3,4-dihydro-2H-pyrrole-2-carboxylic acid, have been studied for their potential biological activities. They can serve as intermediates in the synthesis of biologically active compounds and pharmaceuticals.
  • Synthetic Utility: This compound can act as a building block in organic synthesis, leading to the development of various other complex molecules. The ability to manipulate its structure opens pathways for creative chemical design.
  • Versatile Reactions: 3,4-dihydro-2H-pyrrole-2-carboxylic acid can undergo various reactions, such as cyclization, oxidation, and functional group transformations, making it an attractive compound in organic synthesis.

As a chemistry student, understanding compounds like 3,4-dihydro-2H-pyrrole-2-carboxylic acid is key to appreciating the interconnectedness of chemistry and biology. “Chemistry is all about relationships,” and this compound exemplifies that connection beautifully—working at the crossroads of structural elegance and functional application.

In summary, the study of 3,4-dihydro-2H-pyrrole-2-carboxylic acid enriches our comprehension of organic molecules, showcasing how their unique structures lead to diverse functionalities in both nature and synthetic chemistry.

Synonyms
3,4-dihydro-2H-pyrrole-2-carboxylic acid
2906-39-0
1-pyrroline-5-carboxylic acid
2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-
dl-1-pyrroline-5-carboxylic acid
delta-1-pyrroline-5-carboxylic acid
52TNU46DHL
CHEBI:1372
DTXSID00863056
Delta(1)-pyrroline-5-carboxylic acid
D1-Pyrroline-5-carboxylic acid
delta(1)Pyrroline-5-carboxylate
D1-Pyrroline-5-carboxylate
DL-1-Pyrroline-5-carboxylate
L-Delta 1-pyrroline-5-carboxylate
3,4-dihydro-2h-pyrrole-2-carboxylicacid
UNII-52TNU46DHL
SCHEMBL50356
Delta1-Pyrroline-5-carboxylate
CHEMBL1161508
DTXCID60811735
delta(1)-Pyrroline-5-carboxylate
NS00075367
C04322
dl-1-pyrroline-5-carboxylic acid??discontinued
Q2823196