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3,4-Dichlorobenzylamine

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Identification
Molecular formula
C7H7Cl2N
CAS number
6287-38-3
IUPAC name
(3,4-dichlorophenyl)methanamine
State
State

At room temperature, 3,4-Dichlorobenzylamine is typically a solid, although it can be encountered as a liquid near its melting point. Its state can be influenced by slight impurities, which may lower its melting point.

Melting point (Celsius)
38.00
Melting point (Kelvin)
311.15
Boiling point (Celsius)
257.00
Boiling point (Kelvin)
530.15
General information
Molecular weight
176.05g/mol
Molar mass
176.0400g/mol
Density
1.3093g/cm3
Appearence

3,4-Dichlorobenzylamine is a colorless to pale yellow crystalline solid. The compound may also appear as a yellowish liquid if it is slightly impure or melted. Its structure comprises a benzene ring substituted with two chlorine atoms and an amine group, contributing to its appearance.

Comment on solubility

Solubility of (3,4-dichlorophenyl)methanamine

(3,4-dichlorophenyl)methanamine, with the chemical formula C7H7Cl2N, presents unique solubility characteristics influenced by its molecular structure. Understanding its solubility is essential for applications in various chemical processes.

Solubility Characteristics

The solubility of (3,4-dichlorophenyl)methanamine can be summarized as follows:

  • Polarity: The presence of chlorine atoms increases the polarity of the molecule, hinting at potential solubility in polar solvents.
  • Solvent Compatibility: It is likely to be soluble in:
    • Polar solvents such as water, due to hydrogen bonding potential.
    • Organic solvents like ethanol and acetone, where the non-polar phenyl ring can interact.
  • Limited Solubility: However, its overall solubility may be limited due to the bulky dichlorophenyl group, which can hinder interactions with water molecules.

In conclusion, while (3,4-dichlorophenyl)methanamine may dissolve in certain solvents, its solubility is a balance between its polar and non-polar characteristics, leading to varying solubility in different environments. As with many organic compounds, the specific solvent can greatly influence its behavior.

Interesting facts

Interesting Facts About (3,4-Dichlorophenyl)methanamine

(3,4-Dichlorophenyl)methanamine is a fascinating compound that exemplifies the complex nature of organic chemistry. This compound is characterized by the presence of a chlorinated aromatic ring, which greatly influences its properties and potential applications. Here are some noteworthy insights:

  • Pharmaceutical Relevance: This compound is structurally related to various pharmaceutical agents, particularly in the realm of anti-inflammatory and analgesic drugs. The dichloro substitutions can enhance biological activity and modify the pharmacokinetic properties.
  • Environmental Impact: Chlorinated compounds are known for their environmental persistence. Understanding the degradation pathways of (3,4-dichlorophenyl)methanamine is crucial for evaluating its ecological impact and developing remediation strategies.
  • Reactivity: The amine functional group attached to the aromatic ring provides opportunities for further functionalization. This reactivity is often harnessed in synthetic chemistry to create more complex structures.
  • Structure-Activity Relationship (SAR): The specific position of the chlorine atoms on the phenyl ring plays a pivotal role in influencing the compound's reactivity and interactions with biological targets. Such insights contribute to the field of medicinal chemistry, where optimizing drug efficacy is of paramount importance.
  • Safety Considerations: Due to the presence of chlorine atoms, safety and handling precautions are essential when working with this compound in laboratory settings. Understanding its toxicological profiles is critical for safe usage.

The study of (3,4-dichlorophenyl)methanamine highlights not only its functional potential in various applications but also the importance of chlorinated compounds in science. As chemists continue to investigate this compound, their efforts may lead to significant advancements in both environmental science and medicinal chemistry.

Synonyms
3,4-Dichlorobenzylamine
102-49-8
(3,4-Dichlorophenyl)methanamine
Benzenemethanamine, 3,4-dichloro-
Benzylamine, 3,4-dichloro-
3,4-Dichloro-benzylamine
1-(3,4-dichlorophenyl)methanamine
EINECS 203-035-1
MFCD00008114
NSC 25065
(3,4-Dichlorophenyl)methanamine;(3,4-Dichlorophenyl)methanamine
(3,4-dichlorophenyl)methylamine
3,4-dichlorobenzenemethanamine
NSC25065
3,4-dichlorobezylamine
3,4 dichlorobenzylamine
3,4 dichloro-benzylamine
3,4-dichlorobenzyl-amine
3,4 diChloro benzylamine
(3,4-dichlorobenzyl)amine
Integrase inhibitor, R1{1}
SCHEMBL112200
CHEMBL276152
3,4-Dichlorobenzylamine, 95%
DTXSID9059254
BDBM93339
[(3,4-dichlorophenyl)methyl]amine
(3,4-Dichlorophenyl)methanamine #
Benzylamine, 3,4-dichloro-(8CI)
STR01748
NSC-25065
AKOS000127166
CS-W017422
SY004246
DB-021860
D2451
NS00023152
EN300-248977
InChI=1/C7H7Cl2N/c8-6-2-1-5(4-10)3-7(6)9/h1-3H,4,10H
203-035-1