Skip to main content

Indirubin

ADVERTISEMENT
Identification
Molecular formula
C16H10N2O2
CAS number
479-41-4
IUPAC name
3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione
State
State

At room temperature, Indirubin is a solid. It forms dark red crystals that are typically used in powdered or crystalline form in various applications.

Melting point (Celsius)
283.00
Melting point (Kelvin)
556.15
Boiling point (Celsius)
518.20
Boiling point (Kelvin)
791.35
General information
Molecular weight
262.27g/mol
Molar mass
262.2660g/mol
Density
1.4033g/cm3
Appearence

Indirubin is characterized by its dark red color. It typically appears as a crystalline solid, often forming needle-like crystals.

Comment on solubility

Solubility of 3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione (C16H10N2O2)

The solubility of 3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione is influenced by several factors that dictate how well this compound interacts with various solvents. Here are key considerations regarding its solubility:

  • Polarity: The compound features both hydrophobic indole rings and a polar dione structure. This dual characteristic suggests that it may be soluble in both polar and nonpolar solvents, albeit with varying degrees.
  • Solvent Interaction: It is anticipated that this compound will have improved solubility in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) rather than in aqueous solutions, as the hydrophobic portions may resist interaction with water.
  • Concentration: The solubility can also depend on the concentration of the solute; higher concentrations may lead to saturation effects that limit further solubility.
  • Temperature Effects: As with many organic compounds, an increase in temperature could enhance the solubility, as higher temperatures often reduce solvent viscosity and increase molecular interactions.

In conclusion, while 3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione shows potential for solubility in specific organic solvents, it may pose challenges when interacting with polar solvents like water. Hence, choosing the right solvent is critical for applications involving this compound.

Interesting facts

Interesting Facts about 3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione

The compound 3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione, often referred to in scientific literature as a unique dual indole derivative, has garnered the interest of researchers due to its intriguing chemical structure and potential applications. Here are some fascinating aspects worth noting:

  • Biological Significance: This compound has been studied for its potential biological activities, particularly in the fields of medicinal chemistry and pharmaceuticals. Compounds containing indole structures are known for their diverse biological properties, including anti-cancer and anti-inflammatory activities.
  • Structural Complexity: The intricate fusion of two indole moieties with a pyrrole-2,5-dione framework helps in stabilizing various molecular conformations, which can lead to unique reactivity patterns in synthetic processes or biological interactions.
  • Potential in Materials Science: Due to its pronounced π-conjugated system, the compound may have promising applications in materials science, particularly in organic electronics and photonic devices. Such compounds can exhibit interesting electrical and optical properties.
  • Research Applications: Researchers are exploring the use of this compound as a precursor in the synthesis of other complex organic molecules, which could lead to the discovery of new drugs or materials with desirable properties.

As noted by leading scientists, "The exploration of indole derivatives reveals a wealth of opportunities that lie at the intersection of synthetic chemistry and biological research." This emphasizes the ongoing importance of compounds like 3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione in advancing both theoretical knowledge and practical applications in chemistry.

In summary, the compound's distinctive properties and versatility make it a subject of great interest for ongoing research, underscoring the vital role of understanding complex chemical structures in the development of innovative solutions in science.

Synonyms
bisindolylmaleimide v
113963-68-1
1-Methyl-3,4-bis(3-indolyl)maleimide
3,4-di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione
Ro 31-6045
3,4-bis(1H-indol-3-yl)-1-methylpyrrole-2,5-dione
2,3-bis(1H-Indol-3-yl)-N-methylmaleimide
CHEMBL291725
1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-1-methyl-
3,4-bis(1H-indol-3-yl)-1-methyl-pyrrole-2,5-dione
3,4-bis(1H-indol-3-yl)-1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione
N-Methylbis(indol-3-yl)maleimide
3,4-Di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione
BIM V
Methylarcyriarubin
BisindolylmaleimideV
MFCD00236433
N-Methyl-3,4-bis(indol-3-yl)maleimide
1-Methyl-3,4-bis(indol-3-yl)maleimide
Bisindolylmaleimide deriv. 4
BDBM2582
SCHEMBL3945882
DTXSID50150620
CHEBI:186275
C21H15N3O2
HMS3229B11
HMS3401G13
HMS3648M04
HB0138
HSCI1_000201
NSC767267
AKOS015920082
GS-3766
NSC-767267
SDCCGRCH-0000099.P001
SDCCGSBI-0207136.P006
2,3-bis(indol-3-yl)-N-methylmaleimide
HY-112400
B6143
NS00023703
Bisindolylmaleimide V - CAS 113963-68-1
SR-01000946387
SR-01000946387-1
BRD-K07780396-001-01-5