Interesting facts
Interesting Facts about 3,3,3-Trifluoro-2-hydroxy-2-methyl-N-phenyl-propanamide
3,3,3-Trifluoro-2-hydroxy-2-methyl-N-phenyl-propanamide, often referred to as an intriguing example of the *complex interplay between fluorinated compounds and organic amides*, has garnered attention in both academic and industrial settings. Below are some fascinating insights into this compound:
- Fluorine's Influence: The presence of fluorine atoms significantly alters the physical and chemical properties of the compound. Fluorinated compounds are known for their stability and can exhibit unique reactivity patterns, making them valuable in various applications, including pharmaceuticals.
- Amide Functionality: As an amide, this compound showcases properties typical of amides, such as strong hydrogen bonding. This characteristic enhances its solubility in polar solvents and can influence its biological activities.
- Potential Applications: Due to its structure, this compound could be explored in the fields of medicinal chemistry and agrochemicals. Its trifluoromethyl group may contribute to improved biological activity, potentially leading to innovative therapeutic agents.
- Tantalizing Synthesis: The synthetic pathways leading to this compound can be fascinating, often involving multi-step reactions that require careful control of conditions to ensure the desired functionality is achieved.
- Modifying Biological Interactions: The incorporation of trifluoromethyl groups is known to alter lipophilicity and metabolic stability, thereby enhancing the pharmacological profile of compounds that contain them.
As noted in various studies, such compounds can be pivotal in the quest for new therapeutic agents, with researchers stating that, "the integration of fluorine can effectively improve the selectivity and efficacy of drug candidates." The continuing exploration of compounds like 3,3,3-trifluoro-2-hydroxy-2-methyl-N-phenyl-propanamide emphasizes the vital role of chemical innovation in addressing modern challenges.
Synonyms
CHEMBL72645
Propanamide, 3,3,3-trifluoro-2-hydroxy-2-methyl-N-phenyl-
SCHEMBL6359557
JHSBXNFXGVSVQO-UHFFFAOYSA-N
BDBM50472642
Solubility of 3,3,3-Trifluoro-2-hydroxy-2-methyl-N-phenyl-propanamide
The solubility of 3,3,3-trifluoro-2-hydroxy-2-methyl-N-phenyl-propanamide (C15H12F3NO2) is influenced by several factors due to its unique chemical structure. This compound contains both polar and non-polar functional groups, which can lead to interesting solubility characteristics.
Key Points Regarding Solubility:
In summary, while 3,3,3-trifluoro-2-hydroxy-2-methyl-N-phenyl-propanamide may exhibit some degree of solubility in water, it is generally more compatible with organic solvents due to its mixed polar-nonpolar character. Its solubility behavior can be described as a balance between its functional groups and their interactions with the solvent environment. Understanding these interactions is critical for applications in pharmaceutical and chemical formulations.