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Ceftriaxone

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Identification
Molecular formula
C18H18N8O7S3
CAS number
73384-59-5
IUPAC name
3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State

Ceftriaxone is a solid at room temperature, typically found as a crystalline powder for pharmaceutical preparations.

Melting point (Celsius)
295.00
Melting point (Kelvin)
568.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
554.58g/mol
Molar mass
554.5790g/mol
Density
1.4245g/cm3
Appearence

Ceftriaxone appears as a white to yellowish crystalline powder.

Comment on solubility

Solubility of 3,3-Dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

The solubility of 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (C18H18N8O7S3) can be influenced by several key factors:

  • Polarity: The presence of multiple functional groups, including esters, amides, and a thia ring, affects the overall polarity of the molecule.
  • Hydrophilicity vs. Hydrophobicity: The balance between hydrophilic and hydrophobic groups plays a crucial role in its solubility in water. Compounds with high hydrophilicity tend to be more soluble in polar solvents, while hydrophobic components might favor solubility in organic solvents.
  • Temperature: Increased temperature generally enhances solubility, which allows the compound to dissolve better in solutions.
  • pH of the Solution: The solubility can vary significantly depending on pH, particularly for compounds with acidic or basic groups that can ionize.

In general, compounds with complex structures like this can exhibit:

  1. A range of solubilities in water, potentially low due to the hydrophobic character.
  2. Better solubility in organic solvents such as ethanol or acetonitrile.
  3. Interactions with solvents that can lead to various solubility behaviors based on specific conditions.

As with many organic compounds, the structural features of 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate significantly impact its solubility profile, making it essential for practical applications to consider the solvent system in which the compound is to be used.

Interesting facts

Interesting Facts about 3,3-Dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This compound is a fascinating example of the complexity and diversity found in chemical compounds. Particularly noted for its unique structural features, it is categorized as a bicyclic compound with notable functionalities that contribute to its potential applications.


Chemical Structure

  • Bicyclic Structure: The compound exhibits a bicyclo[3.2.0] framework, which not only makes it intriguing from a synthetic chemistry perspective but also contributes to its biological activities.
  • Functional Groups: The presence of a thia group (sulfur-containing) and amine functionalities adds to the reactivity and potential medicinal properties of this compound.

Potential Applications

The unique structure and functional groups of this compound suggest various possible uses, which may include:

  • Pharmaceuticals: Compounds with such configurations often serve as candidates in drug discovery, particularly in the fields of antibiotics and anti-inflammatory drugs.
  • Chemical Synthesis: Its intricate molecular design may serve as a key intermediate in the synthesis of more complex organic molecules.

Research Interest

Scientists and students alike are drawn to such compounds due to their rich chemistry. Research may focus on:

  • Investigating the compound's bioactivity to understand its therapeutic potential.
  • Studying reaction pathways that lead to its synthesis and degradation.
  • Exploring its structural variations to enhance efficacy or reduce toxicity in medicinal applications.

Quote from a Scientist

As one researcher aptly noted, "The beauty of chemical structures like this one lies not only in their complexity but also in their potential to bring revolutionary changes in the biochemical landscape."

In conclusion, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate serves as a compelling case study in the intersection of structure and function in chemistry. Its diverse properties and potential applications make it a subject worthy of further exploration.

Synonyms
3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
STK177194
AKOS000715052
AKOS021983484
CCG-103309
NCGC00389455-01
3,3-DIMETHYL-7-OXO-6-(2-PHENYLACETAMIDO)-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE