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3,3-diethylpiperidine-2,4-dione

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Identification
Molecular formula
C9H15NO2
CAS number
No data available
IUPAC name
3,3-diethylpiperidine-2,4-dione
State
State

At room temperature, 3,3-diethylpiperidine-2,4-dione is typically a solid. It is stable under normal conditions and used often in organic synthesis.

Melting point (Celsius)
52.00
Melting point (Kelvin)
325.20
Boiling point (Celsius)
275.50
Boiling point (Kelvin)
548.70
General information
Molecular weight
155.21g/mol
Molar mass
155.2100g/mol
Density
1.0835g/cm3
Appearence

3,3-Diethylpiperidine-2,4-dione appears as a solid. It generally presents as a white to off-white crystalline substance.

Comment on solubility

Solubility of 3,3-diethylpiperidine-2,4-dione

3,3-diethylpiperidine-2,4-dione, a compound with intriguing properties, displays variable solubility characteristics that warrant exploration. Understanding its solubility is essential for its application in various chemical processes.

  • Solvent Interaction: This compound tends to exhibit solubility in polar solvents such as ethanol and methanol due to its functional groups that can engage in hydrogen bonding.
  • Water Solubility: While it may not be highly soluble in water, moderate solubility can be expected, influenced by temperature and pH.
  • Organic Solvents: It generally shows good solubility in common organic solvents like chloroform and acetone, which is indicative of its non-polar characteristics.
  • Temperature Sensitivity: The solubility increases with rising temperatures, making it essential to consider the temperature when performing reactions or dissolving the compound.

Notably, as with many organic compounds, solubility can vary significantly based on the specific preparation method and purity of the compound. Hence, when working with 3,3-diethylpiperidine-2,4-dione, it is crucial to conduct preliminary solubility tests to determine its behavior in the intended solvent system.

Interesting facts

Interesting Facts about 3,3-Diethylpiperidine-2,4-dione

3,3-Diethylpiperidine-2,4-dione is a fascinating compound that belongs to the class of piperidine derivatives. Its unique structure and properties open doors to various applications in the field of chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Versatile Derivative: The presence of two ethyl groups on the piperidine ring enhances its solubility and reactivity, making it a useful intermediate in the synthesis of pharmaceuticals and agrochemicals.
  • Biological Significance: Compounds related to piperidine often exhibit a range of biological activities, including analgesic, anti-inflammatory, and central nervous system effects. This makes diethylpiperidine-2,4-dione of interest in drug development.
  • Keto-Enol Tautomerism: Interestingly, 3,3-diethylpiperidine-2,4-dione can exhibit keto-enol tautomerism. This means that it can exist in two forms, the keto form and the enol form, which can have different reactive properties and biological effects.
  • Synthetic Routes: The synthesis of 3,3-diethylpiperidine-2,4-dione can be achieved through various chemical pathways, often involving the reaction of certain amines with diketones, showcasing the structure-activity relationship in organic synthesis.
  • Chemical Investigation: Researchers often explore various substitutions on the piperidine ring to evaluate how changes in the structure can affect the compound's properties, making it a vibrant area of study within organic chemistry.

In conclusion, 3,3-diethylpiperidine-2,4-dione is more than just another piperidine derivative; its structural intricacies and potential applications in pharmaceuticals underline its importance in chemical research. The exploration of such compounds provides invaluable insights that can lead to the development of new therapeutic agents and advanced materials.

Synonyms
PIPERIDIONE
3,3-Diethylpiperidine-2,4-dione
Dihyprylone
77-03-2
Dihyprylon
Piperidion
Ascron
Sedulon
Sedilan
3,3-Diethyl-2,4-dioxopiperidine
3,3-Diethyl-2,4-piperidinedione
Nu 1510
BZ6KL0Q8UD
EINECS 200-999-5
2,4-Piperidinedione, 3,3-diethyl-
NSC 75628
NSC-75628
BRN 0126810
2,4-Dioxo-3,3-diaethylpiperidin [German]
2,4-Dioxo-3,3-diaethylpiperidin
PIPERIDIONE [MI]
PIPERIDIONE [MART.]
PIPERIDIONE [WHO-DD]
DTXSID30227804
NSC75628
PIPERIDIONE (MART.)
UNII-BZ6KL0Q8UD
3,4-dioxopiperidine
2, 3,3-diethyl-
NCIOpen2_000695
SCHEMBL141847
CHEMBL3707370
CHEBI:81302
DTXCID40150295
AAA07703
AKOS022505088
DB13224
HY-W181871
2,4-Dioxo-3,3-diathyltetrahydropyridin
CS-0242945
NS00037875
C17730
EN300-257083
Q7197355
Z1255372924