Interesting facts
Interesting Facts about 3-Pyridylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
3-Pyridylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate is a fascinating compound known for its potential applications in medicinal chemistry. Here are several noteworthy aspects:
- Medicinal Chemistry: This compound features a pyridine ring, which is significant in drug discovery due to its ability to interact with biological targets.
- Anticancer Potential: Research indicates that derivatives of this compound may exhibit activity against various cancer cell lines, making it a candidate for further pharmacological study.
- Mechanism of Action: Its structure suggests it may act as an enzyme inhibitor, particularly in pathways involving carbamoyl transfer, which could be crucial in cancer therapy.
- Structural Diversity: The compound's structure boasts several functional groups, enhancing its potential for creating a library of analogs with varied biological properties.
- Research Interest: With ongoing studies in fields like medicinal chemistry and drug development, attention is growing on how slight modifications can affect the efficacy and safety of this compound.
As a chemist or student exploring this compound, one might consider the implications of its structure-activity relationship (SAR) in drug design, which emphasizes how small changes in a compound's structure can lead to significant differences in its therapeutic effects.
Overall, 3-pyridylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate represents a compelling intersection of organic chemistry and pharmacology, demonstrating the power of chemical compounds in developing new therapeutic strategies.
Synonyms
Entinostat
209783-80-2
ms-275
SNDX-275
MS 275
MS-27-275
Entinostat (MS-275)
SNDX 275
MS 27-275
entinostatum
1ZNY4FKK9H
pyridin-3-ylmethyl 4-((2-aminophenyl)carbamoyl)benzylcarbamate
BAY 86-5274
Carbamic acid, N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-, 3-pyridinylmethyl ester
N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide
ENTINOSTAT [INN]
ENTINOSTAT [JAN]
Entinostat [USAN:INN]
ENTINOSTAT [USAN]
NSC706995
BAY86-5274
pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate
ENTINOSTAT [WHO-DD]
pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
CHEMBL27759
MS-275-27
DTXSID0041068
CHEBI:132082
3-Pyridinylmethyl ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)carbamate
Carbamic acid, ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)-, 3-pyridinylmethyl ester
NSC 706995
NSC-706995
pyridin-3-ylmethyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
ZK 244894
pyridin-3-ylmethyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate
Carbamic acid, N-((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)-, 3- pyridinylmethyl ester
N-[[4-[(2-aminoanilino)-oxomethyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester
Entinostat(MS-27-275)
pyridin-3-ylmethyl (4-((2-aminophenyl)carbamoyl)benzyl)carbamate
pyridin-3-ylmethyl 4-((2-aminophenyl)carbamoyl)benzylcarbamate.
(pyridin-3-yl)methyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate
(Pyridin-3-yl)methyl ((4-((2-aminophenyl)carbamoyl)phenyl)methyl)carbamate
(Pyridin-3-yl)methyl ({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate
N-(2-aminophenyl)-4-[N-(pyridin-3-ylmethoxycarbonyl)aminomethyl]benzamide
Pyridin-3-ylmethyl ({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate
pyridin-3-ylmethyl N-((4-((2-aminophenyl)carbamoyl)phenyl)methyl)carbamate
(pyridin-3-yl)methyl N-((4-((2-aminophenyl)carbamoyl)phenyl)methyl)carbamate
N-((4-((2-aminoanilino)-oxomethyl)phenyl)methyl)carbamic acid 3-pyridinylmethyl ester
N-(2-Aminophenyl)-4-(N-(pyridin-3-yl-methoxycarbonyl)aminomethyl)b enzamide
N-(2-Aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]b enzamide
PYRIDIN-3-YLMETHYL ((4-((2-AMINOPHENYL)CARBAMOYL)PHENYL)METHYL)CARBAMATE
CARBAMIC ACID, N-((4-(((2-AMINOPHENYL)AMINO)CARBONYL)PHENYL)METHYL)-, 3-PYRIDINYLMETHYL ESTER
MFCD08272435
Entinostat, free base
UNII-1ZNY4FKK9H
Entinostat (MS-275)?
benzamide-type inhibitor, 3
HDAC inhibitor SNDX-275
MLS006010183
Entinostat (JAN/USAN/INN)
SCHEMBL148309
Entinostat (MS-27-275)
GTPL7007
DTXCID8021068
BDBM19410
EX-A038
L01XX64
BCPP000155
GLXC-04607
HMS3426G07
HMS3648K12
HMS3654O11
HMS3744O17
BCP01824
HB3983
NSC756642
s1053
Entinostat (MS-275;SNDX-275)
[4-(2-Amino-phenylcarbamoyl)-benzyl]-carbamic acid pyridin-3-ylmethyl ester
3-pyridylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
AKOS024262667
N-(2-Aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide
AC-8968
BCP9000967
Carbamic acid, 3-pyridinylmethyl ester
CCG-208680
CS-0511
DB11841
Entinostat (MS-275, SNDX-275)
FE15194
NSC-756642
SB16665
Carbamic acid, [[4-[[(2-aminophenyl)carbaonyl]phenyl]methyl]-, 3-pyridinylmethyl ester
NCGC00165833-01
NCGC00165833-02
NCGC00165833-03
NCGC00165833-04
NCGC00165833-11
NCGC00165833-13
AS-17906
BP-25653
HY-12163
NCI60_038022
SMR004458705
MS-275, A HDAC1 and HDAC3 inhibitor
E1454
NS00068485
SW219667-1
D09338
EN300-6488260
MS-275,Entinostat, SNDX-275, MS-27-275
SR-01000946382
Q1281020
SR-01000946382-1
BRD-K77908580-001-02-1
BRD-K77908580-001-04-7
BRD-K77908580-001-09-6
BRD-K77908580-001-10-4
Z2037280922
pyridin-3-ylmethyl4-((2-aminophenyl)carbamoyl)benzylcarbamate
N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]-3-pyridinylmethyl ester, carbamic acid
630-693-0
Carbamic acid, ((4-(((2-aminophenyl)amino)carbonyl)phenyl) methyl)-, 3-pyridinylmethyl ester
Carbamic acid, [[4-[[(2-aminophenyl)amino]carbonyl]phenyl] methyl]-, 3-pyridinylmethyl ester (9CI)
N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester;MS 27-275;MS 275
Solubility of 3-pyridylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate
The solubility of the compound 3-pyridylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate, with the chemical formula C20H19NO3, can be quite intricate due to its extensive molecular structure. Such compounds often exhibit varied solubility characteristics depending on the following factors:
As a rule of thumb, it's often stated that "like dissolves like." Therefore, exploring various solvents that mimic the structural characteristics of 3-pyridylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate can yield better solubility outcomes. Testing in both polar and non-polar solvents will provide a clearer understanding of its solubility behavior.