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Phenylpropargylamine

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Identification
Molecular formula
C9H9N
CAS number
None
IUPAC name
3-phenylprop-2-yn-1-amine
State
State

Phenylpropargylamine is typically found in a liquid state at room temperature.

Melting point (Celsius)
-41.00
Melting point (Kelvin)
232.15
Boiling point (Celsius)
218.00
Boiling point (Kelvin)
491.15
General information
Molecular weight
131.17g/mol
Molar mass
131.1740g/mol
Density
0.9834g/cm3
Appearence

Phenylpropargylamine appears as a clear, colorless, or slightly yellow liquid. It may have a characteristic amine odor.

Comment on solubility

Solubility of 3-phenylprop-2-yn-1-amine (C9H9N)

The solubility of 3-phenylprop-2-yn-1-amine, a compound featuring a phenyl group, an alkyne, and an amine functional group, presents some intriguing characteristics.

General Observations

  • Polar and Nonpolar Interactions: The presence of the amine group imparts some degree of polarity to the molecule, which can enhance its solubility in polar solvents. However, the hydrophobic nature of the phenyl group and the alkyne moiety may counterbalance this effect in nonpolar solvents.
  • Solubility in Water: Generally, small amines tend to be more soluble in water due to hydrogen bonding; however, the significant hydrophobic character of this compound may limit its solubility. Expect moderate solubility in water.
  • Solvents of Interest: 3-phenylprop-2-yn-1-amine may exhibit better solubility in organic solvents such as ethanol, acetone, and dichloromethane.

Factors Influencing Solubility

Several factors can impact the solubility of this compound, including:

  1. Temperature: Typically, solubility increases with temperature; thus, increasing the temperature may enhance the dissolution process.
  2. pH Levels: The protonation state of the amine can also affect solubility, as it may alter the compound's polarity. Under acidic conditions, protonation can enhance solubility in water.
  3. Concentration: As with many compounds, high concentrations can also promote solubility due to chemical interactions among molecules.

In summary, while 3-phenylprop-2-yn-1-amine displays some potential for solubility in various solvents, the balance between its polar and nonpolar characteristics suggests a moderate overall solubility profile, especially impacted by external conditions such as temperature and pH.

Interesting facts

Interesting Facts about 3-Phenylprop-2-yn-1-amine

3-Phenylprop-2-yn-1-amine, commonly referred to in chemistry circles as a propargyl amine, is a fascinating compound with several noteworthy characteristics.

Chemical Structure

This compound features a unique alkyne functional group, which is characterized by a carbon-carbon triple bond. The combination of a phenyl group with a propargyl amine structure provides it with distinctive attributes:

  • Hybridization: The terminal alkyne (–C≡C–) is sp-hybridized, contributing to the compound's reactivity.
  • Functional Groups: The presence of both an amine (–NH2) and an alkyne offers potential for diverse chemical reactivity, enabling intriguing synthesis pathways.

Reactivity and Applications

3-Phenylprop-2-yn-1-amine is not just a theoretical interest; it has practical applications across various fields:

  • Pharmaceuticals: This compound is studied for its potential use in drug design, particularly in pharmaceuticals targeting neurological disorders, as the amine functionality may interact favorably with biological systems.
  • Organic Synthesis: Its unique structure allows for its use in coupling reactions and as a building block for more complex organic compounds.

Scientific Significance

According to notable chemists in the field, "Propargyl amines like 3-phenylprop-2-yn-1-amine serve as elegant demonstrations of how minor changes in molecular structure can lead to significant differences in reactivity and application." This principle is vital in the advancement of organic synthesis methodologies.

Furthermore, studying compounds such as 3-phenylprop-2-yn-1-amine broadens our understanding of carbon-rich systems, which play crucial roles in modern chemistry and materials science.

In summary, 3-phenylprop-2-yn-1-amine stands out as a compound with rich chemistry that emphasizes the interplay between structure and reactivity, making it an exciting subject for both chemistry students and professional scientists alike.

Synonyms
3-phenylprop-2-yn-1-amine
78168-74-8
3-Phenyl-2-propyn-1-amine
3-Phenylpropargylamine
3-Phenyl-propargylamine
3-Phenyl-prop-2-ynylamine
CHEMBL110611
2-Propyn-1-amine, 3-phenyl-
MFCD06654553
PPAH
Lopac-P-106
SCHEMBL2386
3-phenyl-prop-2-ynyl-amine
Lopac0_001016
DTXSID70999412
DEHHYUARFKIUDI-UHFFFAOYSA-N
BDBM50026182
AKOS005217509
AB10164
CCG-205096
NCGC00015778-01
NCGC00015778-02
NCGC00162317-01
BS-13289
CS-0530810
EN300-57477
636-068-9