3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanehydroxamic acid

Identification

Molecular formula

C₂₁H₂₁NO₄S

CAS number

134586-31-7

IUPAC name

3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanehydroxamic acid

State

At room temperature, the compound is in a solid state. It is crystalline, which may indicate a consistent melting point thanks to its ordered structure. Depending on the purity and polymorphism, the appearance might slightly vary.

Melting point (Celsius)

151.00

Melting point (Kelvin)

424.15

Boiling point (Celsius)

220.00

Boiling point (Kelvin)

493.15

General information

Molecular weight

355.43g/mol

Molar mass

355.4290g/mol

Density

1.0850g/cm³

Appearence

The compound is typically presented as a crystalline solid, often appearing white or slightly off-white in color. The structure features both aromatic and polar functional groups which can influence its crystallization and purity appearance.

Comment on solubility

Solubility of 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanehydroxamic acid

The solubility of 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanehydroxamic acid, with the chemical formula C₂₁H₂₁NO₄S, can be quite intriguing due to its complex structure. Understanding the solubility helps in predicting the compound's behavior in various environments.

Key Factors Influencing Solubility:

Polarity: The presence of functional groups, such as the sulfonamide and hydroxamic acid moieties, impacts the overall polarity of the compound.
Hydrogen Bonding: The hydroxamic acid group can participate in hydrogen bonding, which may enhance solubility in polar solvents.
Stacking Interactions: The phenyl rings may lead to π-π stacking, potentially influencing solubility in organic solvents.

Generally, compounds that possess both hydrophilic and hydrophobic characteristics tend to have variable solubility across different solvents. Here are some possible solubility characteristics for this particular compound:

Soluble in: Polar solvents such as water and alcohols may show moderate solubility due to hydrogen bonding.
Less soluble in: Non-polar solvents might exhibit lower solubility owing to the presence of polar functional groups.

Ultimately, while laboratory tests would provide the most definitive solubility data, conceptualizing the structural aspects allows for reasonable predictions regarding its solubility behavior. "Understanding solubility is like understanding chemistry itself; it reveals how compounds interact with their environment."

Interesting facts

Interesting Facts about 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanehydroxamic acid

This intriguing compound, 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanehydroxamic acid, stands out due to its unique structural composition and potential applications in the field of medicinal chemistry. Here are some fascinating insights:

Multifunctional Properties: The presence of the hydroxamic acid moiety in the compound allows for interactions with biological targets, which can be crucial in drug development, particularly as enzyme inhibitors.
Potential Anti-Cancer Activity: Compounds with similar structures have shown promise in cancer research, as they may inhibit specific pathways involved in tumor growth and metastasis.
Structure-Activity Relationship (SAR): The complex combination of phenyl groups along with sulfonamide functionality contributes to its biological activity. Understanding how these groups influence interaction with biological molecules is key for optimizing drug efficacy.
Research Focus: Researchers are particularly interested in compounds that can regulate pathways implicated in diseases such as cancer, inflammation, and other metabolic disorders.

As the renowned chemist Linus Pauling stated, “The best way to get a good idea is to have a lot of ideas.” This compound is an excellent example of the sheer creativity and complexity that chemistry can offer, paving the way for novel therapeutic strategies. The synthesis and characterization of such derivatives not only enhance our understanding of chemical interactions but also provide fertile ground for innovative drug design.

In summary, 3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanehydroxamic acid exemplifies the intricate relationship between chemical structure and biological activity, showing how chemistry serves as a cornerstone in the development of life-saving medications.