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3-(p-tolylsulfonyl)prop-2-enenitrile

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Identification
Molecular formula
C10H9NO2S
CAS number
25186-60-5
IUPAC name
3-(p-tolylsulfonyl)prop-2-enenitrile
State
State

At room temperature, 3-(p-tolylsulfonyl)prop-2-enenitrile is typically in the form of a solid. It is stable under normal conditions but should be handled with care due to its chemical nature.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
333.00
Boiling point (Kelvin)
606.15
General information
Molecular weight
205.26g/mol
Molar mass
205.2580g/mol
Density
1.2340g/cm3
Appearence

3-(p-tolylsulfonyl)prop-2-enenitrile appears as a pale yellow to white crystalline solid, often forming as a powder.

Comment on solubility

Solubility of 3-(p-tolylsulfonyl)prop-2-enenitrile

The solubility of the compound 3-(p-tolylsulfonyl)prop-2-enenitrile (C10H9NO2S) can be influenced by several factors. Understanding its solubility characteristics is essential for its applications in various chemical processes.

Key Points on Solubility:

  • Polarity: Due to the presence of both sulfonyl and nitrile functional groups, the polarity of this compound suggests a potential for moderate solubility in polar solvents.
  • Solvent Interaction: It is likely to be soluble in common organic solvents such as acetone, dimethyl sulfoxide (DMSO), and ethanol.
  • Water Solubility: Given its organic structure, it may exhibit limited solubility in water, which is typical for many sulfonamide derivatives.
  • Temperature Effects: Solubility can increase with temperature, a common trend for many organic compounds, enhancing their dissolution in solvents.

In various contexts, the solubility of this compound could be particularly advantageous or limiting, highlighting the importance of conducting thorough solubility tests under different conditions. As with many compounds, accurate solubility data is crucial for optimizing reactions and formulations.

Interesting facts

Exploring 3-(p-tolylsulfonyl)prop-2-enenitrile

3-(p-tolylsulfonyl)prop-2-enenitrile is a fascinating compound that falls within the realm of organic chemistry. This compound is noteworthy for several reasons:

  • Versatility in Reactions: The presence of both the nitrile and sulfonyl functional groups makes this compound highly versatile and reactive, allowing it to participate in a variety of chemical reactions such as nucleophilic additions, condensation reactions, and more.
  • Applications: This compound can serve as a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. The sulfonyl group is often associated with compounds that exhibit biological activity, making it a significant focus in medicinal chemistry.
  • Impact on Drug Design: Designing drugs with sulfonamide or sulfonyl functionalities is a common strategy due to their roles in improving solubility and bioavailability. Compounds like 3-(p-tolylsulfonyl)prop-2-enenitrile, therefore, contribute directly to the development of new therapeutic agents.
  • Regioselectivity: The unique positioning of the functional groups in the structure allows for specific regioselectivity during chemical transformations, which can be a critical parameter in synthetic chemistry.

Overall, 3-(p-tolylsulfonyl)prop-2-enenitrile exemplifies the complexity and importance of organic compounds in the realm of chemical synthesis, drug design, and the development of innovative materials. Its study not only enhances our understanding of organic reactions but also bridges the gap between fundamental chemistry and practical applications.

Synonyms
3-(p-Tolylsulfonyl)acrylonitrile
1424-48-2
3-(4-methylphenyl)sulfonylprop-2-enenitrile
3-(4-Tolylsulfonyl)acrylonitrile
Caswell No. 859A
C10H9NO2S
3-(p-Toluenesulfonyl)acrylonitrile
EPA Pesticide Chemical Code 459200
CP 15749-3
3-((4-Methylphenyl)sulfonyl)-2-propenenitrile
(E)-3-(p-tolylsulfonyl)prop-2-enenitrile
Acrylonitrile, 3-(p-tolylsulfonyl)-
2-Propenenitrile, 3-((4-methylphenyl)sulfonyl)-
Oprea1_624859
KBioGR_000537
KBioSS_000537
IFLab1_000040
DTXSID3041459
KBio2_000537
KBio2_003105
KBio2_005673
KBio3_000973
KBio3_000974
Bio2_000429
Bio2_000909
HMS3651H10
HMS3674K09
3-(4-methylphenyl)sulfonyl-2-propenenitrile
NS00121077
Q27164032