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Oxoglutaric acid

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Identification
Molecular formula
C6H8O5
CAS number
328-50-7
IUPAC name
3-oxohexanedioic acid
State
State

Oxoglutaric acid is a solid at room temperature.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
391.85
Boiling point (Kelvin)
665.00
General information
Molecular weight
146.11g/mol
Molar mass
146.1130g/mol
Density
1.6800g/cm3
Appearence

Oxoglutaric acid appears as a white crystalline solid.

Comment on solubility

Solubility of 3-oxohexanedioic acid (C6H8O5)

3-oxohexanedioic acid, with its chemical formula C6H8O5, exhibits interesting solubility characteristics due to its structure and functional groups. Understanding the solubility of this compound can provide insights into its behavior in various environments. Here are some key points to consider:

  • Water Solubility: This compound is soluble in water due to the presence of multiple carboxylic acid groups that can form hydrogen bonds with water molecules.
  • Solvent Compatibility: In addition to water, 3-oxohexanedioic acid is typically soluble in polar organic solvents such as alcohols, which can enhance its solubility.
  • Temperature Effects: The solubility tends to increase with temperature, making it more soluble in warmer conditions compared to colder ones.
  • pH Dependence: The solubility can also be influenced by the pH of the solution; higher pH levels can lead to increased ionization of the carboxylic acids, enhancing solubility.

These factors underscore the complex nature of solubility for 3-oxohexanedioic acid. As with many organic acids, the balance between hydrophilicity and hydrophobicity plays a crucial role in determining how well this compound can dissolve in various solvents.

Interesting facts

Interesting Facts about 3-Oxohexanedioic Acid

3-Oxohexanedioic acid, also known as 6-oxoheptanedioic acid, is a fascinating compound that plays a significant role in various chemical and biological processes. Here are some intriguing points about this compound:

  • Functional Group Diversity: This compound contains both ketone and carboxylic acid functional groups, which makes it a versatile molecule in organic synthesis.
  • Applications in Biochemistry: 3-Oxohexanedioic acid participates in metabolic pathways and can serve as a key intermediate in the biosynthesis of various natural products.
  • Potential in Pharmaceuticals: Researchers are investigating its derivatives for possible pharmaceutical applications due to their biological activity, including anti-inflammatory properties.
  • Manifold Reactions: The compound can undergo a variety of reactions, such as condensation, oxidation, and esterification, opening avenues for complex molecule synthesis.
  • Role in Synthetic Chemistry: It serves as a useful building block in the preparation of larger polyfunctional compounds, which are invaluable in chemical industries.

As highlighted by various scientific studies, the structural features of 3-oxohexanedioic acid present a unique opportunity for chemists to explore its potential further. The combination of its functionality and versatility makes it an exciting candidate for ongoing research and discovery.

Synonyms
3-oxohexanedioic acid
3-Oxoadipic acid
689-31-6
BETA-KETOADIPIC ACID
beta-ketoadipate
beta-Oxoadipic acid
3-Ketoadipic
3-Ketoadipic acid
Hexanedioic acid, 3-oxo-
3-ketoadipate
.beta.-Ketoadipic acid
3-oxo-adipic acid
3-keto-adipate
3-oxo-hexanedioic acid
1379JRA56F
NSC 18511
NSC-18511
.BETA.-OXOADIPIC ACID
CHEBI:37440
DTXSID30218974
b-oxoadipic acid
beta-Oxoadipate
b-Ketoadipate
UNII-1379JRA56F
b-Oxoadipate
b-Ketoadipic acid
3-Ketoadipic Acid; 3-Oxoadipic Acid; NSC 18511; ss-Ketoadipic Acid; ss-Oxoadipic Acid;
starbld0045478
SCHEMBL218098
DTXCID80141465
RTGHRDFWYQHVFW-UHFFFAOYSA-N
AAA68931
NSC18511
LMFA01170096
DB-183635
NS00125131
C00846
Q27117141
633-254-1