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Acetoacetic acid

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Identification
Molecular formula
C4H6O3
CAS number
541-50-4
IUPAC name
3-oxobutanoic acid
State
State

At room temperature, acetoacetic acid is generally found as a liquid. However, due to its instability, it is commonly available for use in the form of a more stable derivative or in solution.

Melting point (Celsius)
-44.00
Melting point (Kelvin)
229.20
Boiling point (Celsius)
181.00
Boiling point (Kelvin)
454.20
General information
Molecular weight
102.09g/mol
Molar mass
102.0880g/mol
Density
1.1192g/cm3
Appearence

Acetoacetic acid is typically a colorless liquid. In pure form, it can also be encountered as colorless to pale yellow crystals. It is characterized by a strong odor resembling that of vinegar.

Comment on solubility

Solubility of 3-Oxobutanoic Acid

3-Oxobutanoic acid, with the chemical formula C4H6O3, exhibits notable solubility characteristics due to its chemical structure. Being a carboxylic acid, it has the ability to form hydrogen bonds with water, which significantly enhances its solubility. Here are some key points regarding its solubility:

  • Solvent Compatibility: 3-Oxobutanoic acid is expected to be highly soluble in polar solvents, particularly water, due to the presence of its carboxylic group.
  • Aqueous Solutions: When dissolved in water, 3-oxobutanoic acid can dissociate partially, thus contributing to the acidity of the solution.
  • Temperature Influence: As with many organic compounds, the solubility of 3-oxobutanoic acid may increase with rising temperature, promoting better dissolution in aqueous mediums.

In summary, *3-oxobutanoic acid* is likely to be soluble in water, making it a useful compound in various chemical and industrial applications where aqueous solutions are required.

Interesting facts

Interesting Facts about 3-Oxobutanoic Acid

3-Oxobutanoic acid, also known as acetoacetic acid, is a fascinating compound that plays a crucial role in various biochemical processes. Here are some engaging facts about this intriguing acid:

  • Metabolic Significance: It is a key component in the ketogenic diet, acting as an intermediate in the degradation of fatty acids and amino acids, particularly during periods of fasting or carbohydrate restriction.
  • Synthesis of Other Compounds: 3-Oxobutanoic acid is instrumental in synthesizing other biologically important molecules, including various ketones and even some hormones.
  • Industrial Applications: This compound is utilized in the production of various chemical pharmaceuticals and is a precursor for the synthesis of dyes and flavors.
  • Research Potential: Scientists are actively studying 3-oxobutanoic acid for its potential therapeutic roles in managing conditions like obesity and type 2 diabetes. The compound's ability to influence metabolism sparks interest in the field of nutrition science.
  • Structure and Reactivity: The unique structure of 3-oxobutanoic acid gives it interesting reactivity, allowing it to participate in condensation reactions and serve as an important building block in organic synthesis.

This compound is a prime example of how chemistry intersects with biology and medicine, shedding light on new avenues for research and health.

Synonyms
acetoacetic acid
3-oxobutanoic acid
541-50-4
3-oxobutyric acid
acetoacetate
3-ketobutyrate
beta-ketobutyric acid
Butanoic acid, 3-oxo-
diacetic acid
oxobutyrate
Acetoacitic acid
3-Ketobutyric acid
3-oxo-butanoic acid
diacetate
acetylacetic acid
3-OXO-BUTYRIC ACID
UNII-4ZI204Y1MC
3-ketobutanoic acid
4ZI204Y1MC
CHEBI:15344
4387-93-3
DTXSID00202441
3-oxobutanate
3-oxobutanoicacid
AAE
3-Oxobutyrate
lithium-acetoacetate
acetonecarboxylic acid
SCHEMBL6620
.ALPHA.-KETOBUTYRATE
ACETOACETIC ACID [MI]
CHEMBL1230762
SCHEMBL13341499
DTXCID00124932
WDJHALXBUFZDSR-UHFFFAOYSA-N
LMFA01060003
AKOS006241271
DB01762
DB-342173
HY-112540
CS-0046333
NS00068392
C00164
EN300-106488
H27848
Q409692
BRD-K73234506-235-02-1
A6DBA337-E696-4022-A9F9-1757E3CDBFAE
QuadraPure(R) AK, 50-90 mesh, extent of labeling: 2.0-3.0 mmol/g loading, 1 % cross-linked with divinylbenzene