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Paroxetine

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Identification
Molecular formula
C19H20FNO3
CAS number
61869-08-7
IUPAC name
3-oxa-11-azatetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaene-11-carboxamide
State
State

Paroxetine is a solid at room temperature, often processed into tablet form for pharmaceutical use.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
465.20
Boiling point (Kelvin)
738.35
General information
Molecular weight
329.38g/mol
Molar mass
329.3750g/mol
Density
1.4000g/cm3
Appearence

Paroxetine is typically found as a white or off-white crystalline powder. It is often odorless or has a weak characteristic odor.

Comment on solubility

Solubility Properties of 3-oxa-11-azatetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaene-11-carboxamide

The solubility of 3-oxa-11-azatetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaene-11-carboxamide (C19H20FNO3) is characterized by several intriguing features. Being a complex organic compound, understanding its solubility is essential for various applications in the field of chemistry.

Factors Influencing Solubility:

The solubility of this compound can be influenced by numerous factors, including:

  • Polarity: The presence of functional groups such as the carboxamide group enhances its ability to interact with polar solvents.
  • Temperature: As with many compounds, an increase in temperature often leads to an increase in solubility.
  • Solvent Type: This compound is likely to have varying solubility in water and organic solvents. Non-polar solvents may solvate it less effectively compared to more polar environments.

Expected Solubility Behavior:

Based on its structure, one might expect:

  • Moderate solubility in polar solvents such as dimethyl sulfoxide (DMSO) or ethanol due to its carboxamide functionality.
  • Limited solubility in non-polar solvents like hexane or chloroform, primarily because of the lack of non-polar regions within the molecular structure.

In conclusion, while the exact solubility of 3-oxa-11-azatetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaene-11-carboxamide in various solvents may require empirical research, understanding the interactions of its functional groups provides a fundamental insight into its solubility behavior. Further studies can help elucidate the precise solubility characteristics necessary for practical applications.

Interesting facts

Interesting Facts about 3-oxa-11-azatetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaene-11-carboxamide

This compound exemplifies the fascinating world of complex organic molecules found within the realm of medicinal chemistry. Known for its intricate structure, it showcases remarkable bonding patterns and arrangements that are often the subject of extensive research.

Unique Structural Characteristics

Its distinct features include:

  • Multicyclic Framework: The tetracyclic nature of this compound presents unique geometric configurations that can influence its reactivity and interactions with biological systems.
  • Presence of Functional Groups: The carboxamide moiety not only plays a crucial role in forming hydrogen bonds but also enhances solubility and biological activity.
  • Chiral Centers: The stereochemistry involved in this molecule's synthesis can significantly affect its pharmacological properties.

Applications in Science and Medicine

Due to its complex architecture, this compound has potential applications, including:

  • Pharmaceutical Development: Research indicates that compounds with similar structures may exhibit potent biological activities, making them candidates for drug development.
  • Research Tools: The unique configuration may serve as a model for studying various biological processes or for designing new therapeutic agents.

Scientific Significance

As a student or scientist examining this compound, one might consider the statement from renowned chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." This highlights the importance of exploring diverse molecular structures and their potential impacts on health and disease.

In summary, 3-oxa-11-azatetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaene-11-carboxamide serves as a compelling example of how intricate organic compounds can lead to significant advancements in chemistry and medicine.

Synonyms
36507-30-9
Carbamazepine-10,11-epoxide
Carbamazepine 10,11-epoxide
Carbamazepine epoxide
10,11-Epoxycarbamazepine
1a,10b-dihydro-6h-dibenzo[b,f]oxireno[d]azepine-6-carboxamide
Carbamazepine 10,11-oxide
1AH-dibenzo[b,f]oxireno[2,3-d]azepine-6(10bH)-carboxamide
GP 49-023
cbz-e
Carbamazepine-10,11-trans-dihydrodiol
BRN 1219988
CHEBI:3388
UNII-QC9505F279
10,11-Dihydro-10,11-epoxycarbamazepine
6H-Dibenz[b,f]oxireno[d]azepine-6-carboxamide, 1a,10b-dihydro-
Carbamazepine10,11-Epoxide
3-oxa-11-azatetracyclo[10.4.0.02,4.05,10]hexadeca-1(16),5,7,9,12,14-hexaene-11-carboxamide
1a,10b-Dihydro-6H-dibenz(b,f)oxiren(d)azepine-6-carboxamide
DTXSID60891456
QC9505F279
GP-49-023
6H-DIBENZ(b,f)OXIREN(d)AZEPINE-6-CARBOXAMIDE, 1a,10b-DIHYDRO-
1a,10b-Dihydro-6H-dibenz(b,f)oxireno(d)azepine-6-carboxamide
10,11-DIHYDRO-5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE 10,11-EPOXIDE
1-(cyclohexoxycarbonyloxy)ethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
Carbamazepine 10,11-Epoxide (>97% by HPLC)
Carbamazepine 10,11-epoxide, analytical standard
CBZ-10,11-epoxide
1a,10b-Dihydro-6H-dibenzo(b,f)oxireno(d)azepine-6-carboxamide
6H-DIBENZ(B,F)OXIRENO(D)AZEPINE-6-CARBOXAMIDE, 1A,10B-DIHYDRO-
1-(cyclohexoxycarbonyloxy)ethyl 2-ethoxy-3-((4-(2-(2H-tetrazol-5-yl)phenyl)phenyl)methyl)benzimidazole-4-carboxylate
MFCD00467137
CHEMBL1258
Carbamazepin-10,11-epoxide
SCHEMBL156675
DTXCID701030568
HY-W013378R
1a,10b-Dihydro-6H-dibenzo[b,f]oxireno[2,3-d]azepine-6-carboxamide
BDBM50446047
AKOS027327549
CS-W014094
FC19680
HY-W013378
Carbamazepine 10,11-epoxide (Standard)
DS-11818
NS00000327
C07496
Q27106058
Carbamazepine 10,11-Epoxide 1.0 mg/ml in Acetonitrile
Carbamazepine 10,11-epoxide 100 microg/mL in Acetonitrile
1a,10b-Dihydro-6H-dibenzo[b,f]oxireno[2,3-d]azepine-6-carboxamide #
1a,10b-Dihdyro-6H-dibenzo[b,f]oxireno[d]azepine-6-carboxamide;10,11-Dihydro-10,11-epoxycarbamazepine;10,11-Epoxycarbamazepine
3-oxa-11-azatetracyclo[10.4.0.0^{2,4.0^{5,10]hexadeca-1(16),5,7,9,12,14-hexaene-11-carboxamide