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Xylazine

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Identification
Molecular formula
C12H16N2O
CAS number
7361-61-7
IUPAC name
3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methyl-anilino]phenol
State
State
At room temperature, xylazine is in a solid state, typically in the form of a crystalline powder.
Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
220.27g/mol
Molar mass
220.3340g/mol
Density
1.2300g/cm3
Appearence

Xylazine appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methyl-anilino]phenol (C12H16N2O)

The solubility of 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methyl-anilino]phenol can be influenced by several factors, owing to its unique structural characteristics. Here are some key aspects to consider:

  • Polar vs. Non-Polar Solvents: This compound contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions. Thus, its solubility may be higher in mixed solvents, particularly those that balance polarity.
  • pH Sensitivity: The solubility could also be affected by pH levels in the solvent. Compounds with amino groups might ionize, which can increase solubility in more acidic or basic solutions.
  • Temperature Influence: An increase in temperature typically enhances solubility for many solids in liquids. Therefore, evaluating its solubility at varying temperatures may yield different results.
  • Intermolecular Interactions: Strong hydrogen bonding potential within this molecule can lead to varied solubility patterns. Compounds that can form hydrogen bonds with solvents generally have improved solubility.

In conclusion, while the precise solubility of 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methyl-anilino]phenol is best determined through empirical testing in specific solvents, understanding the aforementioned factors plays a crucial role in predicting its behavior in different environments.

Interesting facts

Interesting Facts about 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methyl-anilino]phenol

This complex organic compound is a fascinating example from the world of medicinal chemistry. Known for its diverse applications, it showcases the beauty of structure-activity relationships in drug design.

Key Highlights:

  • Pharmacological Potential: The imidazole moiety often contributes to biological activity, making compounds like this one important for drug development targeting various diseases.
  • Design Innovation: The unique fusion of a phenolic group with an imidazole contributes to its potential as a pharmacophore – a structural feature responsible for its therapeutic effects.
  • Structure Complexity: The presence of multiple functional groups allows for intricate interactions at the molecular level, enhancing its efficacy in biological systems.
  • Research Interest: Ongoing studies frequently explore its potential roles in treating conditions such as cancer, inflammation, and infectious diseases, showcasing its versatility.

As a scientist or chemistry student, it is invigorating to consider the implications of such compounds in pharmaceuticals. The interplay of chemistry and biology exemplifies how slight modifications in structure can lead to profound changes in function. “The magic of chemistry lies in the unseen connections”, one might say, reflecting on the intricate relationships within these molecules.

In conclusion, compounds like 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methyl-anilino]phenol remind us of the vast frontier of organic chemistry and its impact on science and medicine. The continuous exploration of these structures holds the promise for the next generation of therapies.

Synonyms
phentolamine
50-60-2
Regitine
Fentolamin
Regitin
Dibasin
Fentolamina
Phentolaminum
Rogitine
Phenotolamine
Phentalamine
Regitipe
C 7337 Ciba
Phentolamin
Fentolamina [INN-Spanish]
Phentolaminum [INN-Latin]
2-(N-(m-Hydroxyphenyl)-p-toluidinomethyl)imidazoline
Regitina
3-(((4,5-Dihydro-1H-imidazol-2-yl)methyl)(p-tolyl)amino)phenol
C 7337
HSDB 3382
2-(m-Hydroxy-N-p-tolylanilinomethyl)-2-imidazoline
EINECS 200-053-1
3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol
2-((N-(m-Hydroxyphenyl)-p-toluidino)methyl)-2-imidazoline
UNII-Z468598HBV
2-(N'-p-Tolyl-N'-m-hydroxyphenylaminomethyl)-2-imidazoline
BRN 0272944
Phentolamine (INN)
CHEBI:8081
DTXSID4023462
3-{[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol
Z468598HBV
Phenol, m-(N-(2-imidazolin-2-ylmethyl)-p-toluidino)-
2-Imidazoline, 2-((N-(m-hydroxyphenyl)-p-toluidino)methyl)-
Phenol, 3-(((4,5-dihydro-1H-imidazol-2-yl)methyl)(4-methylphenyl)amino)-
MLS000040874
DTXCID703462
5-25-09-00365 (Beilstein Handbook Reference)
Phenol, 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-
NCGC00016311-10
SMR000058051
3-[[(4,5-dihydro-1h-imidazol-2-yl)methyl](4-methylphenyl)amino]phenol
PHENTOLAMINE [INN]
Fentolamina (INN-Spanish)
Phentolaminum (INN-Latin)
Phentolamine [INN:BAN]
Fentolamine
3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOL
CAS-50-60-2
Phentolamine mesylas
phentol amine
Rogitine (Salt/Mix)
Spectrum_000077
3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid
Phentolamine (Standard)
Opera_ID_116
Prestwick0_000230
Prestwick1_000230
Prestwick2_000230
Prestwick3_000230
Spectrum3_000788
Spectrum4_000899
Spectrum5_001704
PHENTOLAMINE [MI]
CHEMBL597
PHENTOLAMINE [HSDB]
cid_5775
SCHEMBL5653
PHENTOLAMINE [VANDF]
Lopac0_000982
Ryzumvi (opthalmic solution)
BSPBio_000279
BSPBio_001435
BSPBio_002496
GTPL502
KBioGR_001338
KBioSS_000477
cid_91430
MLS001201741
DivK1c_000807
PHENTOLAMINE [WHO-DD]
SPBio_002200
BPBio1_000307
BCBcMAP01_000014
BDBM31046
KBio1_000807
KBio2_000477
KBio2_003045
KBio2_005613
KBio3_001716
C04AB01
V03AB36
NINDS_000807
HMS1791H17
HMS1989H17
HMS2089E03
HMS2235D17
HMS3372H21
HMS3402H17
Tox21_110364
BBL010978
HY-12717R
STK802099
AKOS004119917
Tox21_110364_1
CCG-205062
DB00692
FP37047
SDCCGSBI-0050955.P005
CAS-73-05-2
IDI1_000807
SMP1_000236
NCGC00016311-01
NCGC00016311-02
NCGC00016311-03
NCGC00016311-04
NCGC00016311-05
NCGC00016311-06
NCGC00016311-07
NCGC00016311-08
NCGC00016311-09
NCGC00016311-11
NCGC00016311-12
NCGC00016311-13
NCGC00016311-14
NCGC00016311-15
NCGC00016311-16
NCGC00016311-17
NCGC00016311-19
NCGC00016311-33
NCGC00021804-06
NCGC00021804-07
NCGC00021804-08
NCGC00021804-09
NCGC00021804-10
HY-12717
SBI-0050955.P004
DB-050268
CS-0012293
NS00007720
EN300-51916
2-((N-(m-Hydroxyphenyl)-p-toluidino)methyl)-
D08362
G78138
AB00053768-28
AB00053768_29
AB00053768_30
L001116
Q420360
m-[N-(2-Imidazolin-2-ylmethyl)-p-toluidino]phenol
BRD-K90333595-001-02-8
BRD-K90333595-003-04-0
BRD-K90333595-003-21-4
BRD-K90333595-003-22-2
BRD-K90333595-066-16-1
BRD-K90333595-066-17-9
Z732246520
2-(N-p'-Tolyl-N-(m'-hydroxyphenyl)aminomethyl)imidazoline
3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol #
3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol
3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl-(4-methylphenyl)-amino]phenol
3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride
3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid
3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid
200-053-1