Skip to main content

3-Methyl-2-phenylmorpholine

ADVERTISEMENT
Identification
Molecular formula
C11H15NO
CAS number
4318-56-3
IUPAC name
3-methyl-2-phenyl-morpholine
State
State

At room temperature, 3-Methyl-2-phenylmorpholine is typically found in a liquid state.

Melting point (Celsius)
-14.00
Melting point (Kelvin)
259.15
Boiling point (Celsius)
254.50
Boiling point (Kelvin)
527.65
General information
Molecular weight
177.25g/mol
Molar mass
177.2470g/mol
Density
1.0553g/cm3
Appearence

3-Methyl-2-phenylmorpholine is typically a colorless liquid. However, based on purity and storage conditions, slight yellowish hues may be observed. It has a characteristic amine-like odor and is often clear, without any suspended particles.

Comment on solubility

Solubility of 3-methyl-2-phenyl-morpholine

3-methyl-2-phenyl-morpholine, with the chemical formula C11H15NO, exhibits interesting solubility characteristics that are important for various applications.

In general, the solubility of organic compounds like 3-methyl-2-phenyl-morpholine can be influenced by several factors:

  • Polarity: Due to the presence of the morpholine ring, this compound exhibits moderate polarity, which enhances its solubility in polar solvents such as water and alcohols.
  • Hydrophobic and Hydrophilic Balance: The aromatic phenyl group contributes to the hydrophobicity, while the amine functional group improves interaction with polar solvents.
  • Temperature Effects: Solubility may increase with temperature, allowing for better dissolution in aqueous or organic solvents.
  • pH Sensitivity: The solubility may also vary significantly with changes in pH, especially if protonation of the amine occurs, enhancing solubility in acidic media.

It's important to note that:

  1. **Experimentation** is often necessary to determine the exact solubility of this compound in various solvents.
  2. The solubility could determine its application in pharmaceutical formulations or chemical syntheses.

In summary, 3-methyl-2-phenyl-morpholine has moderate solubility in polar solvents due to the interplay between its polar and nonpolar components, making it a versatile compound for various chemical contexts.

Interesting facts

Interesting Facts About 3-methyl-2-phenyl-morpholine

3-methyl-2-phenyl-morpholine is a fascinating compound with unique characteristics and potential applications. As a member of the morpholine family, this compound features a heterocyclic structure which is notable for its nitrogen-containing ring. Here are some compelling highlights:

  • Applications in Pharmaceuticals: Morpholine derivatives are often utilized in drug design due to their ability to enhance solubility and bioavailability. The presence of the phenyl and methyl groups in this compound may contribute to its pharmacological properties, making it a candidate for further investigation in medicinal chemistry.
  • Agrochemicals: The unique structure of 3-methyl-2-phenyl-morpholine can be advantageous in the development of agrochemicals, specifically pesticides and herbicides. Compounds like this can help in targeting pests while minimizing environmental impact.
  • Research in Organic Synthesis: This compound serves as a valuable intermediate in organic synthesis, where it can be used to produce more complex molecules. Its ability to participate in various chemical reactions makes it an important building block for synthetic chemists.
  • Insights into Structure-Activity Relationships: The distinct substitution patterns on the morpholine ring can provide insights into how modifications affect biological activity. This aspect allows chemists to explore structure-activity relationships (SAR) effectively.
  • Chemical Stability: Morpholine derivatives are generally known for their stability under different conditions, which adds to their appeal in both industrial applications and research settings.

As with any chemical compound, safety and regulation are critical. Understanding the toxicological profile of 3-methyl-2-phenyl-morpholine is essential for its application in various fields. Therefore, ongoing research is necessary to unlock its full potential.

In summary, 3-methyl-2-phenyl-morpholine is more than just a chemical entity; it represents a promising avenue for innovation across diverse scientific disciplines.

Synonyms
phenmetrazine
3-Methyl-2-phenylmorpholine
Oxazimedrine
Phenmetrazin
134-49-6
Fenmetrazin
Defenmetrazin
2-Phenyl-3-methylmorpholine
Fenmetrazina
Psychamine A 66
Probese-P
Morpholine, 3-methyl-2-phenyl-
Phenmetrazinum
Dexphenmetrazine
Preludin
Fenmetrazina [INN-Spanish]
Phenmetrazinum [INN-Latin]
Phenmetrazine [INN:BAN]
2-Fenyl-3-methylmorfolin
3-Methyl-2-phenyltetrahydro-2H-1,4-oxazine
2-Fenyl-3-methylmorfolin [Czech]
HSDB 3156
dl-2-Phenyl-3-methyltetrahydro-1,4-oxazine
EINECS 205-143-4
BRN 0140490
CHEBI:8067
Phenmetraline
DTXSID5023455
DEA No. 1631
Fenmetrazina (INN-Spanish)
Phenmetrazinum (INN-Latin)
NCGC00164535-01
NCGC00164535-02
S-trans-Phenmetrazine
SCHEMBL33984
DTXCID603455
CHEMBL1201208
134-49-6 (free)
HCA91912
AKOS003662804
AB07481
DB00830
AC-16023
NS00002554
C07432
2-PHENYL-3-METHYLTETRAHYDRO-1,4-OXAZINE
Q3329406
205-143-4
57919-12-7