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3-Methyl-2-oxopentanoic acid

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Identification
Molecular formula
C6H10O3
CAS number
2650-37-1
IUPAC name
3-methyl-2-oxo-pentanoic acid
State
State

At room temperature, 3-Methyl-2-oxopentanoic acid is typically a liquid. It is stable under normal conditions of use and storage, although it may react with strong oxidizing agents.

Melting point (Celsius)
-38.00
Melting point (Kelvin)
235.15
Boiling point (Celsius)
239.00
Boiling point (Kelvin)
512.15
General information
Molecular weight
130.14g/mol
Molar mass
130.1410g/mol
Density
1.0270g/cm3
Appearence

3-Methyl-2-oxopentanoic acid typically appears as a colorless liquid with a slight fruity odor. It is soluble in water and commonly available in a solution.

Comment on solubility

Solubility of 3-methyl-2-oxo-pentanoic acid (C6H10O3)

The solubility of 3-methyl-2-oxo-pentanoic acid is an intriguing topic due to its unique chemical structure. This acidic compound exhibits different solubility characteristics based on various factors:

  • Polarity: As a carboxylic acid, 3-methyl-2-oxo-pentanoic acid contains a carboxyl group (-COOH) that increases its polarity, allowing it to interact favorably with polar solvents like water.
  • Hydrogen Bonding: The presence of both a carbonyl group (C=O) and a hydroxyl group (-OH) enhances hydrogen bonding capability, further promoting solubility in aqueous solutions.
  • Alkyl Chain Influence: The 3-methyl substituent adds a hydrophobic character to the molecule, which can affect solubility in non-polar solvents. Generally, this compound will have limited solubility in non-polar environments.

Overall, 3-methyl-2-oxo-pentanoic acid is expected to be:

  • Soluble in water due to its polar nature and ability to form hydrogen bonds.
  • Less soluble in organic solvents such as hexane, where hydrophobic interactions dominate.

In summary, the solubility of this compound is a balance of its functional groups and the size of the alkyl chain, making it an interesting subject for further exploration in various solvent systems.

Interesting facts

Interesting Facts about 3-Methyl-2-oxo-pentanoic Acid

3-Methyl-2-oxo-pentanoic acid, often referred to in scientific literature as an important metabolic intermediate, offers fascinating insights into both biochemistry and industrial applications. Here are several notable points about this compound:

  • Metabolic Role: This compound plays a significant role in the metabolism of certain amino acids and fatty acids, specifically in pathways related to energy production.
  • Versatile Precursor: It serves as a key precursor in the synthesis of various pharmaceuticals and agrochemicals, showcasing its utility in both health and agricultural sectors.
  • Biological Relevance: Its derivatives can exhibit biological activity, making them of great interest in medicinal chemistry for potential therapeutic applications.
  • Research Potential: Scientists are particularly interested in studying this compound's reactivity and how its structural properties can be modified to enhance its functionalities.
  • Synthesis Awareness: The compound can be synthesized through several methods, often involving mild reaction conditions, which makes it an attractive option for green chemistry initiatives.

As quoted by leading researchers, "Understanding the intricate pathways involving 3-methyl-2-oxo-pentanoic acid not only illuminates classical biochemical processes but also opens up new avenues for innovation in pharmaceuticals and sustainable chemistry."
The exploration of this compound reflects a harmonious blend of theoretical study and practical application, making it a cornerstone for both current research and industrial innovation.

Synonyms
3-Methyl-2-oxovaleric acid
1460-34-0
3-Methyl-2-oxopentanoic acid
alpha-Keto-beta-methylvaleric acid
ketoisoleucine
3-Ethyl-3-methylpyruvic acid
3-Methyl-2-oxovaleric
2-oxo-3-methyl-n-valeric acid
2-oxoisoleucine
Pentanoic acid, 3-methyl-2-oxo-
2-Oxo-3-methylpentanoic acid
3-methyl-2-oxo-pentanoic acid
787T50HCIV
39748-49-7
(1)-3-Methyl-2-oxovaleric acid
2-OXO-3-METHYLVALERIC ACID
EINECS 215-955-0
EINECS 254-616-1
MFCD00002582
alpha-keto-beta-methyl-n-valeric acid
2-keto methylvalerate
2-Oxo-3-methylvalerate
CHEBI:35932
DTXSID50862670
2-keto-3-methylvaleric acid
DL-3-METHYL-2-OXOPENTANOATE
alpha-Keto-beta-methylvalerate
(+/-)-3-methyl-2-oxopentanoic acid
DL-3-METHYL-2-OXOVALERIC ACID
VALERIC ACID, 3-METHYL-2-OXO-
DL-3-ETHYL-3-METHYLPYRUVIC ACID
DL-3-METHYL-2-OXOPENTANOIC ACID
3-METHYL-2-OXOVALERIC ACID, DL-
DL-3-METHYL-2-OXO PENTANOIC ACID
3-METHYL-2-OXOPENTANOIC ACID [FHFI]
.ALPHA.-OXO-.BETA.-METHYLVALERIC ACID
FEMA NO. 3870, ACID-(+/-)-
.ALPHA.-KETO-.BETA.-METHYLVALERIC ACID
.ALPHA.-OXO-.BETA.-METHYL-N-VALERIC ACID
3-METHYL-2-OXOPENTANOIC ACID, (+/-)-
.ALPHA.-KETO-.BETA.-METHYL-N-VALERIC ACID
2-oxokolavenate
alpha-oxo-beta-methylvaleric acid
2-oxokolavenic acid
alpha-oxo-beta-methyl-n-valeric acid
a-Oxo-b-methylvalerate
a-Keto-b-methylvalerate
3-methyl-2-oxo-Valerate
a-Oxo-b-methyl-n-valerate
a-Oxo-b-methylvaleric acid
3-methyl-2-oxo-pentanoate
a-keto-b-Methyl-n-valerate
a-Keto-b-methylvaleric acid
2-Oxo-3-methyl-n-valerate
3-methyl-2-oxo-Valeric acid
a-Oxo-b-methyl-n-valeric acid
a-keto-b-Methyl-n-valeric acid
alpha-Oxo-beta-methyl-n-valerate
(3R)-3-Methyl-2-oxopentanoate
alpha-keto-beta-methyl-n-valerate
UNII-787T50HCIV
(+/-)-3-methyl-2-oxovaleric acid
C03465
3-Methyl-2-oxopentanoicacid
SCHEMBL43232
2-keto-3-methyl-valeric acid
DTXCID30203608
AKOS006220526
HY-113063R
3-Methyl-2-oxovaleric acid (Standard)
AS-58809
FM157432
SY058109
3-Methyl-2-oxopentanoic acid, AldrichCPR
DB-304731
HY-113063
CS-0059473
K0020
NS00014564
F16679
EN300-1852217
Q23905808
Z1205493610
215-955-0