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β-Hydroxybutyric acid

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Identification
Molecular formula
C4H8O3
CAS number
300-85-6
IUPAC name
3-hydroxybutanoic acid
State
State

At room temperature, β-Hydroxybutyric acid can be a solid or a liquid, depending on the conditions and grading of the sample. It may be found as crystalline granules or as liquefied acid.

Melting point (Celsius)
43.00
Melting point (Kelvin)
316.15
Boiling point (Celsius)
163.00
Boiling point (Kelvin)
436.15
General information
Molecular weight
104.10g/mol
Molar mass
104.1050g/mol
Density
1.1695g/cm3
Appearence

β-Hydroxybutyric acid is usually encountered as a colorless, crystalline solid or as a liquid. In its solid form, it consists of white crystals.

Comment on solubility

Solubility of 3-hydroxybutanoic acid (C4H8O3)

3-hydroxybutanoic acid is a fascinating compound, particularly in terms of its solubility properties. Understanding its solubility can help reveal its behavior in various environments. Here are some key points to note:

  • Water Solubility: 3-hydroxybutanoic acid is considered to be highly soluble in water. This characteristic is primarily due to its ability to form hydrogen bonds with water molecules, facilitated by its hydroxyl (-OH) and carboxylic acid (-COOH) functional groups.
  • Polarity: The compound's polar functional groups contribute to its hydrophilicity, making it readily dissolve in polar solvents like water.
  • Solvent Compatibility: In addition to water, 3-hydroxybutanoic acid can also dissolve in organic solvents such as ethanol and acetone, although the solubility may vary depending on the solvent's polarity.
  • Temperature Effects: As with many organic acids, increasing temperature generally increases the solubility of 3-hydroxybutanoic acid in aqueous solutions.

In summary, the solubility of 3-hydroxybutanoic acid in water and other polar solvents enhances its utility in various chemical and biological applications. Its substantial solubility can be attributed to its polar nature and the ability to interact with water molecules.

Interesting facts

Interesting Facts about 3-Hydroxybutanoic Acid

3-Hydroxybutanoic acid, often referred to as a key intermediate in various biochemical pathways, is a fascinating compound with significant implications in both biology and industry. This compound is a member of the family of hydroxy acids and plays a crucial role in cellular metabolism.

Biological Significance

One of the notable aspects of 3-hydroxybutanoic acid includes:

  • Metabolic Pathway: It is a key component in the β-oxidation pathway, which converts fatty acids into energy.
  • Precursor to Ketone Bodies: It serves as a precursor to important ketone bodies, providing an alternative energy source during periods of low carbohydrate intake.

Industrial Applications

In addition to its biological relevance, 3-hydroxybutanoic acid has sparked interest in various industrial applications:

  • Bioplastics: It is utilized in the production of biodegradable plastics, contributing to a more sustainable future.
  • Cosmetic Formulations: Its moisturizing properties have made it a popular ingredient in skincare products.

Research and Innovation

Ongoing research continues to uncover potential uses for 3-hydroxybutanoic acid:

  • Scientists are studying its role in food preservation due to its antimicrobial properties.
  • Its potential in therapeutic applications, especially concerning metabolic disorders, is a promising area of investigation.

As we explore the versatility of 3-hydroxybutanoic acid, its contributions to both science and industry highlight the compound's remarkable importance. As the saying goes, "In chemistry, the simplest compounds can lead to the most profound discoveries."

Synonyms
3-hydroxybutyric acid
3-hydroxybutanoic acid
300-85-6
Butanoic acid, 3-hydroxy-
625-71-8
DL-3-Hydroxybutyric Acid
beta-Hydroxybutyric acid
3 HBA
3-Hydroxybuttersaeure
Butyric acid, 3-hydroxy-
DL-beta-Hydroxybutyric acid
beta-Hydroxybuttersaeure
26063-00-3
beta-Hydroxy-n-butyric acid
poly(3-hydroxybutyric acid)
3 Hydroxybutyrate
3-hydroxy-butanoic acid
.beta.-Hydroxybutyric acid
(1)-3-Hydroxybutyric acid
(+-)-3-Hydroxybutyric acid
beta-hydroxy-butyrate
D,l-3 hydroxybutyrate
beta-hydroxybutanoic acid
NSC 3806
NSC-3806
Hydroxybutyric acid, dl-
MFCD00004546
.beta.-Hydroxy-n-butyric acid
AI3-21675
(+/-)-3-Hydroxybutyric Acid
D(-)-beta-hydroxy butyric acid
CHEBI:20067
3-hydroxybutyric acid, (+/-)-
TZP1275679
3-hydroxy-butyrate
Butyric acid, 3-hydroxy- (8CI)
3-Hydroxybutanoic Acid + 3-(3-Hydroxybutyryloxy)butyric Acid (CAS:7565-79-9) (50:50 Mixture)
SMR000112209
(+/-)-3-Hydroxybutyric Acid (Technical Grade)
MFCD00137685
UNII-TZP1275679
EINECS 206-099-9
EINECS 210-908-0
3-OH-butyric acid
BHBA
3- hydroxybutyric acid
3-hydroxy-butyric acid
DL-3-HydroxybutyricAcid
d,l-3-hydroxybutyric acid
bmse000161
bmse000905
SCHEMBL2731
(RS)-3-hydroxybutyric acid
(+/-)-beta-Hydroxybutyrate
MLS001332397
MLS001332398
3-Hydroxybutyric acid, 95%
DL-.beta.-Hydroxybutyric acid
(+/-)-3-Hydroxybutanoic acid
CHEMBL1162496
.BETA.HYDROXYBUTYRIC ACID
DTXSID60859511
NSC3806
(.+/-.)-3-Hydroxybutyric acid
3-Hydroxybutyric acid, tech grade
HMS2270C20
HMS3369F13
BBL027467
HB4640
LMFA01050005
s1031
STL377875
AKOS009156821
AB88579
AC-5701
FH30882
SB44475
Butanoic acid, 3-hydroxy-, (+/-)-
.BETA.-HYDROXYBUTYRIC ACID [MI]
Butanoic acid, 3-hydroxy-, (A+/-)-
BETA-HYDROXYBUTYRIC ACID [WHO-DD]
FP179872
SY074781
SY076545
SY114480
VS-08544
HY-113378
CS-0062335
H0228
NS00014717
Poly(3-hydroxybutyric acid), MW~500,000
D84191
EN300-147463
Poly[(R)-3-hydroxybutyrate], Mn ~500,000
Q223092
BRD-A41387824-001-06-0
(+/-)-3-Hydroxybutanoic acid;DL-?-Hydroxybutyric acid
869DD3C9-3114-4BE2-B4A6-6F1787476E95