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Pyridoxal hydrochloride

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Identification
Molecular formula
C8H10ClNO3
CAS number
65-22-5
IUPAC name
3-hydroxy-5-(hydroxymethyl)-2-methyl-pyridine-4-carbaldehyde;hydrochloride
State
State

At room temperature, pyridoxal hydrochloride is in a solid state, typically as a crystalline powder.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
203.63g/mol
Molar mass
203.6300g/mol
Density
1.4000g/cm3
Appearence

Pyridoxal hydrochloride appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 3-hydroxy-5-(hydroxymethyl)-2-methyl-pyridine-4-carbaldehyde;hydrochloride

The compound 3-hydroxy-5-(hydroxymethyl)-2-methyl-pyridine-4-carbaldehyde; hydrochloride (C8H10ClNO3) demonstrates notable solubility characteristics that are essential for its applications in various chemical processes. Its solubility can be influenced by several factors:

  • Polarity: The presence of polar functional groups such as hydroxyl (-OH) and aldehyde (-CHO) enhances the compound's affinity for polar solvents like water.
  • Hydrochloride Form: As a hydrochloride salt, it is typically more soluble in aqueous solutions compared to its free base, which can significantly improve its bioavailability in pharmaceutical contexts.
  • Temperature: Increasing temperature generally improves the solubility of many organic compounds, including this pyridine derivative, making it more effective in high-temperature reactions or formulations.

In summary, 3-hydroxy-5-(hydroxymethyl)-2-methyl-pyridine-4-carbaldehyde; hydrochloride is expected to be soluble in polar solvents, particularly water, which makes it useful for applications requiring aqueous solutions. This solubility profile is crucial, as it facilitates the compound's use in various chemical and biological studies.

Interesting facts

Exploring 3-Hydroxy-5-(Hydroxymethyl)-2-Methyl-Pyridine-4-Carbaldehyde Hydrochloride

3-Hydroxy-5-(hydroxymethyl)-2-methyl-pyridine-4-carbaldehyde hydrochloride is a fascinating compound that bridges the realms of organic chemistry and medicinal applications. Here are some interesting facts to consider:

  • Structural Significance: This compound contains a pyridine ring, which is a fundamental structure in many natural products and pharmaceuticals. The functional groups attached to the ring increase its versatility.
  • Biological Activity: Compounds with similar structures have been known to exhibit significant biological activities, making them candidates for drug development. This highlights the importance of such chemical entities in medicinal chemistry.
  • Hydrochloride Form: Being in its hydrochloride form enhances the solubility and stability of the compound, a common practice in pharmaceutical formulations to improve bioavailability.
  • Synthesis Pathways: The synthesis of this compound can involve various methodologies, often leveraging reactions that modify existing pyridine derivatives, showcasing the creativity involved in organic synthesis.
  • Analytical Techniques: The study of this compound typically employs sophisticated analytical techniques such as NMR, IR spectroscopy, and mass spectrometry, which allow chemists to confirm the structural integrity of the compound.

In summary, 3-hydroxy-5-(hydroxymethyl)-2-methyl-pyridine-4-carbaldehyde hydrochloride is not just another organic compound; it stands at a crossroads of chemical and biological interest, influencing research in fields from pharmaceuticals to organic synthesis. Quoting renowned chemists, "All the great discoveries are made in the space between charts." This compound exemplifies such discovery potential.

Synonyms
PYRIDOXAL HYDROCHLORIDE
65-22-5
Pyridoxal HCl
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride
PL HCl
MFCD00012809
2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine hydrochloride
Pyridoxal, hydrochloride
EINECS 200-602-5
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde, hydrochloride
3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde hydrochloride
1416KF0QBC
3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde hydrochloride
NSC-19613
CHEBI:131529
PYRIDOXAL HYDROCHLORIDE [MI]
4-Pyridinecarboxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methyl-, hydrochloride
PYRIDOXAL HYDROCHLORIDE [WHO-DD]
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde HCl
3-Hydroxy-5-(hydroxymethyl)-2-methyl-isonicotinaldehyde hydrochloride
4-formyl-3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-1-ium chloride
4-Pyridinecarboxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methyl-, hydrochloride (1:1)
UNII-1416KF0QBC
Pyridoxal galactoside
SCHEMBL50601
Pyridoxal hydrochloride, 99%
CHEMBL543846
DTXSID0058774
BCP09066
AC1788
s3111
AKOS008966955
4-Pyridinecarboxaldehyde, hydrochloride
FP31539
HY-W027446
MP04427
WLN: T6NJ B1 CQ DVH E1Q &GH
AC-30879
AS-15123
BP-12520
Pyridoxal hydrochloride, >=99% (HPLC)
Pyridoxal hydrochloride, >=99.5% (T)
SY036134
DB-054778
CS-0071470
NS00079075
P0559
EN300-17336
Pyridoxal hydrochloride 100 microg/mL in Methanol
3-Hydroxy-5-hydroxymethyl-2-methyl-4-pyridinal, HCl
Q27225156
2Methyl3hydroxy4formyl5hydroxymethylpyridine hydrochloride
F0001-1752
3Hydroxy5(hydroxymethyl)2methylisonicotinaldehyde, hydrochloride
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehydehydrochloride
3-Hydroxy-5-hydroxymethyl-2-methylisonicotinaldehyde hydrochloride
3Hydroxy5(hydroxymethyl)2methyl4pyridinecarboxaldehyde hydrochloride
3-Hydroxy-5-hydroxymethyl-2-methyl-pyridine-4-carbaldehyde hydrochloride
4Pyridinecarboxaldehyde, 3hydroxy5(hydroxymethyl)2methyl, hydrochloride
200-602-5
Pyridoxal hydrochloride, BioReagent, suitable for cell culture, suitable for insect cell culture