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Guanosine monophosphate

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Identification
Molecular formula
C10H14N5O8P
CAS number
85-32-5
IUPAC name
[3-hydroxy-5-(6-oxo-3H-purin-9-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

Guanosine monophosphate is a crystalline solid at room temperature.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
363.22g/mol
Molar mass
363.2200g/mol
Density
2.3000g/cm3
Appearence

Guanosine monophosphate (GMP) typically appears as a white or off-white crystalline powder. It is odorless and has a slightly salty taste.

Comment on solubility

Solubility of [3-hydroxy-5-(6-oxo-3H-purin-9-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate (C10H14N5O8P)

This compound, primarily known for its role in biochemical processes, exhibits a notable solubility profile. Understanding its solubility properties can provide significant insights into its behavior in biological systems and its potential applications. Here are some key points regarding its solubility:

  • Polar Nature: The presence of multiple functional groups, including hydroxyl (-OH) and phosphate (-PO42-), contributes to its overall polarity.
  • Water Solubility: Because of its polar characteristics, [3-hydroxy-5-(6-oxo-3H-purin-9-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate is expected to be soluble in water. This solubility makes it readily bioavailable in physiological conditions.
  • Influence of pH: The solubility can vary with changes in pH, particularly due to the ionization of the phosphate group. Under acidic conditions, the solubility may increase further as more protons can interact with the anionic phosphate.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules enhances its solubility, as these interactions facilitate the dissolution process.
  • Comparative Solubility: It is essential to compare the solubility of this compound with related purine derivatives to understand its unique characteristics better.

In conclusion, while generalizations can be made, the solubility of [3-hydroxy-5-(6-oxo-3H-purin-9-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate primarily portrays a strong compatibility with aqueous environments, vital for its utilization in pharmaceutical and biochemical applications.

Interesting facts

Interesting Facts about [3-hydroxy-5-(6-oxo-3H-purin-9-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This compound is a fascinating derivative of purine and plays a crucial role in various biochemical processes. Here are some key points to consider:

  • Biological Importance: This compound is closely related to nucleotides, which are the building blocks of nucleic acids like DNA and RNA. Understanding its structure can aid in the study of genetic material and cellular functions.
  • Potential Applications: Research on this compound may reveal therapeutic potentials, especially in the fields of oncology and virology, due to its structural similarity to nucleoside analogs that inhibit viral replication or cancer cell growth.
  • Mechanistic Insights: Investigating how this compound interacts with enzymes involved in phosphorylation can shed light on energy transfer and signaling pathways vital for cellular metabolism.
  • Innovative Research: As scientists explore the enantioselective synthesis of this compound, it could lead to the development of more effective pharmaceuticals with fewer side effects.
  • Structural Features: The unique combination of a tetrahydrofuran ring and a purine moiety offers intriguing possibilities for modifying its reactivity and specificity in biochemical reactions.

In summary, [3-hydroxy-5-(6-oxo-3H-purin-9-yl)tetrahydrofuran-2-yl]methyl dihydrogen phosphate represents an exciting area of study within biochemistry. Its intricate structure and potential implications in health and disease make it a subject worth exploring further!