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Pravastatin

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Identification
Molecular formula
C23H36O7
CAS number
81093-37-0
IUPAC name
3-hydroxy-4-[2-[[3-hydroxy-6-methyl-4-[[3-methyl-2-[[3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoyl]amino]propanoylamino]-6-methyl-heptanoic acid
State
State

Pravastatin is typically a solid at room temperature, often found in its stable crystalline form.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
424.55g/mol
Molar mass
424.5520g/mol
Density
1.0980g/cm3
Appearence

Pravastatin appears as a white to off-white crystalline powder. It is usually supplied as a sodium salt to improve its solubility and stability.

Comment on solubility

Solubility of 3-hydroxy-4-[2-[[3-hydroxy-6-methyl-4-[[3-methyl-2-[[3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoyl]amino]propanoylamino]-6-methyl-heptanoic acid

The solubility of the compound with the formula C23H36O7 is of paramount interest due to its complex structure and functional groups. In general, solubility can be influenced by several factors including polarity, hydrogen bonding, and molecular size. For this specific compound, we can consider the following factors:

  • Polarity: The presence of multiple hydroxyl (-OH) groups contributes to a higher polarity, which often enhances solubility in polar solvents such as water.
  • Molecular Size: Larger molecules may exhibit decreased solubility due to steric hindrance. This compound is quite large, which could limit its solubility compared to smaller analogs.
  • Functional Groups: The amine and carboxylic acid functional groups can engage in hydrogen bonding, which may facilitate solubility in water and other polar solvents.
  • Temperature Effects: It's essential to note that solubility can increase with temperature. Thus, this compound may have variable solubility based on environmental conditions.

In conclusion, the solubility of this compound is expected to be influenced by its unique structural features. While we can hypothesize that it may dissolve reasonably well in polar solvents due to its functional groups, the overall large size could pose challenges to complete solubility. As noted in various studies, “the intricate balance between polarity and molecular size is crucial in determining the solubility of complex compounds.”

Interesting facts

Interesting Facts about 3-hydroxy-4-[2-[[3-hydroxy-6-methyl-4-[[3-methyl-2-[[3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoyl]amino]propanoylamino]-6-methyl-heptanoic acid

3-hydroxy-4-[2-[[3-hydroxy-6-methyl-4-[[3-methyl-2-[[3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoyl]amino]propanoylamino]-6-methyl-heptanoic acid is a complex compound with numerous intriguing characteristics that make it worthy of study in the field of chemistry. Here are some interesting points to consider:

  • Biological Relevance: This compound belongs to a category of molecules that may have important roles in biological systems, particularly in the realms of pharmacology and biochemistry.
  • Structure Complexity: The intricate structure features multiple amino acid-derived functional groups, which could suggest potential applications in drug design and molecular synthesis.
  • Potential for Peptide Synthesis: The presence of various amine and acid groups enables the possibility of forming peptides, which are critical in various biological functions and therapeutic applications.
  • Derivative Potential: As a derivative of classical amino acids, it serves as a foundation for synthesizing new compounds that may exhibit enhanced biochemical properties.
  • Research Implications: Compounds with such extensive carbon chains and functional groups are often the subject of research exploring their interactions within biological pathways and metabolic processes.

Scientists continue to explore complex molecules like this one, yielding insights that can lead to the development of innovative therapies and biocatalysts. As underscored by notable chemists, "The beauty of chemistry lies in the complexity it allows us to understand and manipulate." This summarizes the essence of researching compounds with elaborate structures.

The study of 3-hydroxy-4-[2-[[3-hydroxy-6-methyl-4-[[3-methyl-2-[[3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoyl]amino]propanoylamino]-6-methyl-heptanoic acid exemplifies the interdisciplinary nature of chemical science, bridging organic chemistry, medicinal chemistry, and molecular biology in its applications.

Synonyms
NSC272671
39324-30-6
N-(3-Methyl-1-oxobutyl)-L-valyl-L-valyl-4-amino-3-hydroxy-6-methylheptanoyl-L-alanyl-4-amino-3-hydroxy-6-methylheptanoic acid
Pepstatin A (Synthetic)
CHEMBL38526
SCHEMBL19665773
IPA-3998-PI
DTXSID60860364
HMS3374B07
HMS3745M07
IPA-4397-V
IPA-4397
Pepstatin A (Purity Higher than 90% by HPLC)
Heptanoic acid, N-(3-methyl-1-oxobutyl)-L-valyl-L-valyl-4-amino-3-hydroxy-6-methylheptanoyl-L-alanyl-4-amino-3-hydroxy-6-methyl-
Isovaleryl-L-Valyl-L-Valyl[(3S,4S)-4-Amino-3-Hydroxy-6-Methylheptanoyl]-L-Alanyl [(3S,4S)-4-Amino-3-Hydroxy-6-Methylheptanoic Acid]
N-(3-Methylbutanoyl)valyl-N-[1-({1-[(1-carboxy-2-hydroxy-5-methylhexan-3-yl)amino]-1-oxopropan-2-yl}amino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]valinamide