3-hydroxy-2-methyl-1,1-dioxo-1λ6,2-benzothiazin-4-one

Identification

Molecular formula

C₁₃H₁₁N₃O₄S

CAS number

129-50-8

IUPAC name

3-[hydroxy-(2-pyridylamino)methylene]-2-methyl-1,1-dioxo-1lambda6,2-benzothiazin-4-one

State

At room temperature, this compound is typically a solid. Its solid state is consistent with its molecular structure which includes aromatic rings and several functional groups that increase intermolecular forces, maintaining its rigidity.

Melting point (Celsius)

195.00

Melting point (Kelvin)

468.15

Boiling point (Celsius)

362.00

Boiling point (Kelvin)

635.15

General information

Molecular weight

326.31g/mol

Molar mass

326.3500g/mol

Density

1.6200g/cm³

Appearence

The compound is usually in the form of crystals. It typically appears as a yellowish to beige crystalline solid reflecting its organic nature and intricate structure that include sulfur and nitrogen heteroatoms.

Comment on solubility

Solubility of 3-[hydroxy-(2-pyridylamino)methylene]-2-methyl-1,1-dioxo-1lambda6,2-benzothiazin-4-one

The compound 3-[hydroxy-(2-pyridylamino)methylene]-2-methyl-1,1-dioxo-1lambda6,2-benzothiazin-4-one, represented by the chemical formula C₁₃H₁₁N₃O₄S, displays varied solubility characteristics that are fundamental to its application in chemical formulations.

In general, the solubility of this compound can be characterized as:

Polar characteristics: The presence of hydroxyl groups (–OH) and nitrogen atoms in the benzothiazin structure suggests an affinity for polar solvents such as water.
Potential for hydrogen bonding: The functional groups may create opportunities for hydrogen bonding, enhancing solubility in polar mediums.
Solvent dependency: Its solubility might vary significantly with the choice of solvent; while it may dissolve well in polar solvents, it may display reduced solubility in non-polar solvents like hexane.

It is often observed that compounds with complex structures such as this one exhibit:

Low to moderate solubility in water, determined by the balance of hydrophilic and hydrophobic interactions.
Enhanced solubility in organic solvents or mixtures that can better accommodate its molecular structure.

Ultimately, understanding the specific solubility properties of this compound is crucial for its effective use in various applications. As noted, “*The right solvent can make all the difference*,” highlighting the importance of carefully selecting conditions for optimal performance.

Interesting facts

Interesting Facts about 3-[hydroxy-(2-pyridylamino)methylene]-2-methyl-1,1-dioxo-1lambda6,2-benzothiazin-4-one

This compound belongs to the fascinating class of benzothiazinone derivatives, which are well-known for their significant biological activities. Here are some intriguing points about this compound:

Potential Therapeutics: Compounds of this class have shown promise as potential therapeutic agents, particularly in the treatment of bacterial infections. Their unique molecular structure enables them to interact effectively with biological targets.

Mechanism of Action: The presence of the sulfonyl group in the structure is critical as it allows for a variety of interactions with proteins and enzymes, potentially disrupting pathogenic processes.

Research Interest: The exploration of benzothiazinones has spurred significant research interest, particularly in the context of drug development for Mycobacterium tuberculosis, the causative agent of tuberculosis. Scientists are keen on understanding how modifications in the structure can enhance efficacy and reduce resistance.

Synthetic Challenge: The synthesis of this compound may involve intricate organic reactions, showcasing the skill required in the field of synthetic chemistry. This complexity often inspires chemists to develop innovative synthetic pathways.

As a noteworthy compound, 3-[hydroxy-(2-pyridylamino)methylene]-2-methyl-1,1-dioxo-1lambda6,2-benzothiazin-4-one not only demonstrates the remarkable nature of organic compounds but also opens up avenues for research into new treatment strategies against some of the most challenging infectious diseases today.