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3-Phosphoglyceric acid

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Identification
Molecular formula
C3H7O7P
CAS number
820-11-1
IUPAC name
3-hydroxy-2-phosphonooxy-propanoic acid
State
State

At room temperature, 3-phosphoglyceric acid is found in a crystalline solid state.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
186.06g/mol
Molar mass
186.0610g/mol
Density
2.2000g/cm3
Appearence

3-Phosphoglyceric acid is a white crystalline solid.

Comment on solubility

Solubility of 3-hydroxy-2-phosphonooxy-propanoic acid

3-hydroxy-2-phosphonooxy-propanoic acid (C3H7O7P) exhibits unique solubility characteristics due to its chemical structure, which features both hydroxyl (–OH) and phosphonic acid groups. These functional groups significantly enhance its solubility in water. Here are some key points regarding its solubility:

  • High Water Solubility: The presence of multiple hydroxyl groups allows for extensive hydrogen bonding with water molecules, promoting solubility.
  • pH Dependency: The solubility may vary with pH, as changes in acidity can affect the ionization of the phosphonic acid group, further influencing its solubility behavior.
  • Temperature Effects: As with many organic compounds, solubility can increase with an increase in temperature, though the extent of this increase may vary.
  • Solvent Interactions: While primarily soluble in water, its interaction with various organic solvents could yield different solubility profiles, depending on the solvent's polarity.

In summary, the solubility of 3-hydroxy-2-phosphonooxy-propanoic acid is predominantly characterized by its strong affinity for water, making it a hydrophilic compound. This property opens up numerous possibilities for its applications in biological and chemical contexts.

Interesting facts

Interesting Facts about 3-Hydroxy-2-phosphonooxy-propanoic Acid

3-Hydroxy-2-phosphonooxy-propanoic acid, commonly known as HPPA, is a fascinating compound with several intriguing attributes within the realm of biochemistry and synthetic organic chemistry. Here are some noteworthy points:

  • Structure & Function: The presence of both hydroxyl and phosphonate groups in its structure allows HPPA to participate in a variety of biochemical processes. This combination provides the compound with unique properties that can serve both as a metabolite and as a key participant in biochemical pathways.
  • Metabolic Role: HPPA is implicated in the metabolism of certain amino acids and plays an important role in developmental processes. It can influence cellular functions due to its phosphonic acid moiety, which is known to interact with various biological macromolecules.
  • Synthesis & Applications: The synthesis of HPPA can be achieved through various methods, including those involving phosphorus chemistry. Its derivatives are often explored for potential uses in agriculture as herbicides, and its unique functionalities may allow it to act as a chemical building block for developing pharmaceutical agents.
  • Biochemical Interest: Research has shown that compounds like HPPA can modulate metabolic pathways, leading to the exploration of their role as biochemical probes. "Understanding these interactions can revolutionize our approach to treatment and prevention of metabolic disorders," remarks a leading biochemist.
  • Phosphonate Chemistry: As a phosphonate derivative, HPPA provides a distinctive case study in phosphorus chemistry. Researchers are particularly interested in phosphonates for their versatility and potential therapeutic applications, including antiviral properties.

In summary, 3-Hydroxy-2-phosphonooxy-propanoic acid embodies the complexities of chemical compounds that bridge multiple disciplines, including organic synthesis, biochemistry, and pharmacology. Its multifaceted roles make it a subject of ongoing research and interest among scientists striving to unlock new possibilities within chemical science.

Synonyms
2-phosphoglyceric acid
2-phosphoglycerate
2553-59-5
3-hydroxy-2-phosphonooxypropanoic acid
glycerate 2-phosphate
DL-2-Phosphoglycerate
2-P-glycerate
2-P-D-glycerate
3-hydroxy-2-(phosphonooxy)propanoic acid
2-Phospho-DL-glyceric acid
Glyceric acid 2-phosphate
Glyceric acid-2-phosphate
D-2-phosphoglyceric acid
L-2-Phosphoglyceric acid disodium salt hydrate
2-P-glyceric acid
2-P-D-glyceric acid
2-pg
SCHEMBL77985
CHEBI:24344
DTXSID20948430
2-(dihydrogen phosphate)Glycerate
3-Hydroxy-2-phosphonooxypropanoate
DAA44357
2-(dihydrogen phosphate)Glyceric acid
AKOS040758631
PD041462
propanoic acid, 3-hydroxy-2-phosphonooxy-
HY-113167
CS-0062328
Propanoic acid, 3-hydroxy-2-(phosphonooxy)
Propanoic acid, 3-hydroxy-2-(phosphonooxy)-
Glyceric acid, 2-(dihydrogen phosphate) (8CI)
Q209469
Propanoic acid, 3-hydroxy-2-(phosphonooxy)- (9CI)
D60B5ED3-6117-4D39-B1A5-E346FCBBC78C
L-Glycerate2-phosphatedisodiumsalt,disodiuml-2-phosphoglycerate