Skip to main content

3-Hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine

ADVERTISEMENT
Identification
Molecular formula
C9H15N5O
CAS number
1421-11-4
IUPAC name
3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine
State
State

This compound is solid at room temperature and can form crystalline powders when isolated.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
240.00
Boiling point (Kelvin)
513.15
General information
Molecular weight
223.25g/mol
Molar mass
223.2700g/mol
Density
1.3200g/cm3
Appearence

3-Hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine (C9H15N5O)

The solubility of 3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine is a noteworthy aspect of this compound, influencing its potential applications significantly. This compound, characterized by its unique structure, exhibits properties that can be analyzed as follows:

  • Polarity: Due to the presence of multiple nitrogen atoms and the hydroxyl group, the compound is likely to have polar characteristics, which can enhance its solubility in polar solvents.
  • Dissolution Behavior: In aqueous environments, the interaction of the hydroxyl group with water molecules may facilitate the solubility of this compound, making it more soluble in water than in non-polar solvents.
  • Effects of Functional Groups: The presence of the piperidyl moiety can also impact solubility, possibly increasing solubility in certain organic solvents due to its hydrophobic nature.
  • Temperature Influence: Solubility can also vary with temperature; as with many organic compounds, increasing the temperature may enhance solubility.

In conclusion, the solubility of 3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine is influenced by its molecular structure, functional groups, and the nature of the solvent used. This compound's ability to dissolve in various solvents plays a critical role in determining its effectiveness in practical applications.

Interesting facts

Interesting Facts about 3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine

This compound, known for its intricate structure and diverse applications, belongs to the class of pyrimidine derivatives. Pyrimidines play a crucial role in both organic chemistry and biochemistry, serving as significant building blocks in various biological systems.

Key Characteristics

  • Role in Pharmaceuticals: Compounds with similar structures are often explored in medicinal chemistry for their potential in treating various diseases, including cancer and infectious illnesses.
  • Biological Significance: The presence of the piperidine group may enhance the pharmacokinetic properties, facilitating better interactions with biological targets.
  • Research Interest: Its unique imino group contributes to the compound's reactivity and potential for forming covalent bonds, making it a subject of interest in synthetic organic chemistry.

Potential Applications

  • It may be utilized in developing antimicrobial agents.
  • Could serve as a precursor for synthesizing other complex molecules in research.
  • Its structure implies a possible role in creating inhibitors for various enzymatic processes.

As chemists continue to explore the synthesis and applications of 3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine, the hopes for innovative therapeutic agents remain high. This compound epitomizes the exciting interface of chemistry with medicinal developments, showcasing the endless possibilities that arise from the fusion of simple elements into complex molecules.

Synonyms
minoxidil
38304-91-5
Rogaine
Loniten
Minoximen
Regaine
Theroxidil
Alopexil
Alostil
Tricoxidil
Lonolox
Normoxidil
Prexidil
Minodyl
Pierminox
RiUP
Mintop
2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide
6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
U-10858
3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
MFCD00063409
CHEBI:6942
6-(piperidin-1-yl)pyrimidine-2,4-diamine 3-oxide
U-10,858
6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine
NSC-757106
6-(1-piperidinyl)-2,4-pyrimidinediamine-3-oxide
MLS000028566
DTXSID9040685
6-amino-2-imino-4-(piperidin-1-yl)-1,2-dihydropyrimidin-1-ol
6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide
Minossidile [Italian]
Minoxidilum [INN-Latin]
NCGC00015673-08
Minoxidilum
SMR000058963
CAS-38304-91-5
Rogaine for Men
Apo-Gain
6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide
2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate
DTXCID7020685
Neoxidil
Avacor and Mintop
SMR000326812
Loniten (TN)
Rogaine (TN)
Riup (TN)
2,4-Diamino-6-piperidinopyrimidine 3-oxide
SR-01000075331
SR-05000001479
Regaine For Men
Minoxidil,(S)
Regaine For Women
Prestwick_521
3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine
TM-160
Men''''s Rogaine
Women''''s rogaine
Rogaine Extra Strength
pyrimidin-1(2H)-ol
Spectrum_000969
Tocris-0583
MINOXIDIL [INN]
MINOXIDIL [JAN]
MINOXIDIL [MI]
Minoxidil Extra Strength
MINOXIDIL [HSDB]
MINOXIDIL [USAN]
regid855572
Opera_ID_1150
Prestwick0_000020
Prestwick1_000020
Prestwick2_000020
Prestwick3_000020
Spectrum2_001053
Spectrum3_000509
Spectrum4_000063
Spectrum5_001299
Lopac-M-4145
MINOXIDIL [VANDF]
M1389
CHEMBL802
MINOXIDIL [MART.]
M 4145
MINOXIDIL [USP-RS]
MINOXIDIL [WHO-DD]
Minoxidil (U-10858)
Minoxidil (JAN/USP/INN)
CBiol_001798
Lopac0_000786
SCHEMBL29698
BSPBio_000059
BSPBio_001385
BSPBio_002037
KBioGR_000105
KBioGR_000585
KBioSS_000105
KBioSS_001449
MLS000859953
MLS001077294
DivK1c_000160
SCHEMBL232565
SPECTRUM1500415
Minoxidil - Bio-X trade mark
SPBio_001006
SPBio_001980
BPBio1_000065
CHEMBL609587
GTPL4254
Minoxidil, >=99% (TLC)
SGCUT00112
MINOXIDIL [ORANGE BOOK]
CHEMBL1372483
MINOXIDIL [EP MONOGRAPH]
BCBcMAP01_000193
BDBM81463
CHEBI:92128
HMS500H22
KBio1_000160
KBio2_000105
KBio2_001449
KBio2_002673
KBio2_004017
KBio2_005241
KBio2_006585
KBio3_000209
KBio3_000210
KBio3_001537
MINOXIDIL [USP MONOGRAPH]
NINDS_000160
ZFMITUMMTDLWHR-UHFFFAOYSA-N
BCPP000162
Bio1_000084
Bio1_000573
Bio1_001062
Bio2_000105
Bio2_000585
HMS1361F07
HMS1568C21
HMS1791F07
HMS1920P03
HMS1989F07
HMS2089L08
HMS2091F20
HMS2095C21
HMS2233E04
HMS2235N21
HMS3259P21
HMS3262M14
HMS3266O06
HMS3371E15
HMS3372M19
HMS3402F07
HMS3411G16
HMS3675G16
HMS3712C21
Pharmakon1600-01500415
BCP01409
CAS_4201
HY-B0112
NSC_4201
to_000070
VQB71866
Tox21_110193
Tox21_500786
BDBM50237593
CCG-40112
HB1094
MFCD00072128
NSC757106
s1383
STL453211
AKOS015920078
AKOS016339636
Tox21_110193_1
6-amino-2-imino-4-(piperidin-1-yl)
AC-5271
BCP9000929
CCG-220020
CS-1867
DB00350
FD26009
GS-3605
KS-5164
LP00786
NC00686
SDCCGSBI-0050764.P005
IDI1_000160
IDI1_033855
SMP1_000192
NCGC00015673-01
NCGC00015673-02
NCGC00015673-03
NCGC00015673-04
NCGC00015673-05
NCGC00015673-06
NCGC00015673-07
NCGC00015673-09
NCGC00015673-10
NCGC00015673-11
NCGC00015673-13
NCGC00015673-20
NCGC00018278-01
NCGC00018278-02
NCGC00018278-03
NCGC00018278-04
NCGC00024666-01
NCGC00024666-02
NCGC00024666-03
NCGC00024666-04
NCGC00024666-05
NCGC00024666-06
NCGC00024666-07
NCGC00024666-08
NCGC00179672-01
NCGC00261471-01
BD164673
PD003089
SY075383
SBI-0050764.P004
2,6-Diamino-4-piperidinopyrimidine 1-Oxide
5965120SH1
AB00513797
EU-0100786
NS00014997
D00418
EN300-121204
H10337
O10620
U10858
6-(1-Piperidinyl)-2,4-pyrimidinediamine3-oxide
AB00052047-08
AB00052047_09
AB00052047_10
AB00513797-02
A824098
Q424165
SR-01000075331-1
SR-01000075331-3
SR-01000075331-5
SR-05000001479-1
SR-05000001479-2
2,4-DIAMINO-6-PIPERIDINOPYRIMIDINE 3-OXIDE.
3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine
BRD-K06902185-001-05-2
BRD-K06902185-001-10-2
BRD-K06902185-001-16-9
BRD-K06902185-001-17-7
BRD-K06902185-003-01-7
BRD-K14888893-001-02-3
BRD-K14888893-001-14-8
Minoxidil, British Pharmacopoeia (BP) Reference Standard
Z1541638524
Minoxidil, European Pharmacopoeia (EP) Reference Standard
2-azanylidene-3-oxidanyl-6-piperidin-1-yl-pyrimidin-4-amine
6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidino-pyrimidine
Minoxidil, United States Pharmacopeia (USP) Reference Standard
Minoxidil for system suitability, European Pharmacopoeia (EP) Reference Standard
6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide;2,4-Diamino-6-piperidinopyrimidine 3-N-oxide