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Nicotelline

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Identification
Molecular formula
C10H12N2O2
CAS number
5650-85-1
IUPAC name
3-hydroxy-1-methyl-5-(3-pyridyl)pyrrolidin-2-one
State
State

At room temperature, Nicotelline is typically in a solid state.

Melting point (Celsius)
79.00
Melting point (Kelvin)
352.00
Boiling point (Celsius)
283.00
Boiling point (Kelvin)
556.00
General information
Molecular weight
176.22g/mol
Molar mass
176.2150g/mol
Density
1.2244g/cm3
Appearence

This compound typically appears as colorless crystals that may have a characteristic odor.

Comment on solubility

Solubility of 3-hydroxy-1-methyl-5-(3-pyridyl)pyrrolidin-2-one

The solubility of 3-hydroxy-1-methyl-5-(3-pyridyl)pyrrolidin-2-one (C10H12N2O2) can be influenced by several factors, primarily its molecular structure and the presence of functional groups. Here’s what we can summarize about its solubility:

  • Polarity: The presence of hydroxyl (-OH) and pyridine groups suggests that this compound may exhibit moderate to good solubility in polar solvents such as water.
  • Molecular Interactions: The hydroxyl group can form hydrogen bonds with water, enhancing its aqueous solubility.
  • Solvent Compatibility: It may also dissolve in organic solvents like methanol or ethanol, indicating a level of soluble diversity.
  • pH Dependency: Its solubility may vary with pH due to ionization changes of the functional groups, suggesting a potentially nuanced solubility profile in biological or environmental systems.

Overall, while specific solubility data may vary, the characteristics of 3-hydroxy-1-methyl-5-(3-pyridyl)pyrrolidin-2-one indicate a promising level of solubility in various solvents, making it a compound of interest in both research and application scenarios. Understanding these solubility traits can be crucial for its usage in pharmaceuticals and other chemical processes.

Interesting facts

Interesting Facts about 3-Hydroxy-1-Methyl-5-(3-Pyridyl)pyrrolidin-2-One

3-Hydroxy-1-methyl-5-(3-pyridyl)pyrrolidin-2-one, often referred to in scientific literature as a pyrrolidine derivative, is a compound that has attracted attention in various research domains due to its unique structure and potential applications. Here are some engaging insights into this intriguing molecule:

  • Biological Significance: The compound is structurally related to numerous biologically active molecules, making it a crucial subject of study for medicinal chemists. It is explored for its potential as a therapeutic agent in pharmacology.
  • Neuroactive Properties: Pyrrolidine derivatives are known to exhibit various neuroactive effects, which has led to research investigating their role in neuropharmacology and their potential to affect cognitive functions.
  • Research Applications: This compound is of interest in studies targeting neurological disorders. Researchers are delving into its ability to modulate neurotransmitter systems.
  • Synthesis and Development: The synthesis of pyrrolidine-based compounds like this one often involves multiple reaction steps, providing insights into innovative synthetic methodologies and reaction mechanisms in organic chemistry.
  • Potential for Drug Design: With the increasing importance of structure-activity relationships (SAR) in drug design, compounds like this serve as valuable scaffolds for developing new pharmaceuticals tailored for specific diseases.

As with many compounds in the realm of organic chemistry, the study of 3-hydroxy-1-methyl-5-(3-pyridyl)pyrrolidin-2-one offers a glimpse into the complex interplay between structure and biological activity, embodying the essence of what makes chemistry both challenging and rewarding.

Synonyms
2-Pyrrolidinone, 3-hydroxy-1-methyl-5-(3-pyridinyl)-
79581-34-3
3-hydroxy-1-methyl-5-pyridin-3-ylpyrrolidin-2-one
3-hydroxy-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one
(3S,5S)-3'-HYDROXYCOTININE
SCHEMBL4538005
CHEBI:181957
XOKCJXZZNAUIQN-UHFFFAOYSA-N
AKOS026719402
(+)-trans-3'-Hydroxycotinine (unlabeled)
NS00010478
F2185-0729