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Hexadecyloxypropyltrimethylammonium phosphate

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Identification
Molecular formula
C23H50NO5P
CAS number
31971-98-1
IUPAC name
(3-hexadecoxy-2-methoxy-propyl) 2-(trimethylammonio)ethyl phosphate
State
State

At room temperature, Hexadecyloxypropyltrimethylammonium phosphate is a solid. It may range from a powder to a waxy solid depending on hydration and formulation.

Melting point (Celsius)
60.00
Melting point (Kelvin)
333.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
481.73g/mol
Molar mass
481.7280g/mol
Density
1.2000g/cm3
Appearence

This compound typically appears as a white to off-white solid. Some versions may have a waxy appearance depending on the purity and specific formulation. It is typically odorless.

Comment on solubility

Solubility of (3-hexadecoxy-2-methoxy-propyl) 2-(trimethylammonio)ethyl phosphate

The compound (3-hexadecoxy-2-methoxy-propyl) 2-(trimethylammonio)ethyl phosphate, with the formula C23H50NO5P, exhibits some intriguing properties regarding its solubility. Generally, the solubility of such a compound will depend on several key factors:

  • Hydrophobic and Hydrophilic Balance: With its long hydrophobic hexadecyl chains, this compound tends to show lesser solubility in water, making it more soluble in organic solvents.
  • Ionic Nature: The presence of the trimethylammonio group adds a cationic character, which can enhance solubility in polar solvents compared to neutral compounds.
  • Concentration Effects: At higher concentrations, phase separation may occur, leading to different solubility behaviors based on environmental conditions.

As a primary rule of thumb, like dissolves like; thus, you can expect that this compound would find greater solubility in a solvent that has a similar hydrophobic character. This is particularly true for long-chain phosphates, where the balance between hydrophobic alkyl portions and hydrophilic phosphate groups plays a significant role in determining their solubility profile. Understanding these patterns can aid in predicting the compound's behavior in various applications.


Interesting facts

Interesting Facts about (3-hexadecoxy-2-methoxy-propyl) 2-(trimethylammonio)ethyl phosphate

(3-hexadecoxy-2-methoxy-propyl) 2-(trimethylammonio)ethyl phosphate is a unique compound that belongs to the category of phospholipids. These compounds are vital in biological systems, primarily forming the structural framework of cell membranes. Below are some fascinating facts that highlight the significance and properties of this compound:

  • Biological Relevance: This compound can mimic or integrate into biological membranes, playing a crucial role in cellular signaling and membrane dynamics.
  • Amphiphilic Nature: The presence of both a hydrophobic (hexadecyl) tail and hydrophilic (trimethylammonium) head allows this compound to self-assemble, forming micelles or bilayers in aqueous environments.
  • Fatty Acid Derivatives: The hexadecyloxy group, derived from palmitic acid, enhances the lipophilicity of the compound, influencing its interaction with lipid bilayers and potentially making it useful in drug delivery systems.
  • Surface Activity: Compounds like this often exhibit surfactant properties, meaning they can reduce surface tension, making them suitable for applications in emulsion formations and other industrial processes.
  • Potential Applications: The biomimetic properties of this compound suggest uses in various fields, including pharmaceuticals, cosmetics, and nanotechnology.

Moreover, research into compounds like (3-hexadecoxy-2-methoxy-propyl) 2-(trimethylammonio)ethyl phosphate continues to expand our understanding of lipid chemical biology. As we discover more about such **phospholipid variants**, we can better comprehend their role in health and disease, leading to innovative therapeutic strategies.

Synonyms
1-O-Hexadecyl-2-O-methyl-rac-glycero-3-phosphocholine
1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
1-HEXADECYL-2-METHYLGLYCERO-3 PC
BML3-F01
SCHEMBL2734390
CHEMBL1495105
HMS1361E17
HMS1791E17
HMS1989E17
HMS3402E17
(3-hexadecoxy-2-methoxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
NCGC00161383-01
NCGC00161383-02
NCGC00161383-03
NCGC00179212-01
PD050177
1- O- hexadecyl- 2- O- methyl- sn- glyceryl- 3- phosphorylcholine
3-(Hexadecyloxy)-2-methoxypropyl (2-(trimethylammonio)ethyl) phosphate