Skip to main content

3-Fluoropropane-1,2-diol

ADVERTISEMENT
Identification
Molecular formula
C3H7FO2
CAS number
136310-29-5
IUPAC name
3-fluoropropane-1,2-diol
State
State

At room temperature, 3-fluoropropane-1,2-diol is typically in a liquid state. It is stable under normal conditions and is used in various chemical syntheses and applications.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
212.50
Boiling point (Kelvin)
485.65
General information
Molecular weight
94.08g/mol
Molar mass
94.0780g/mol
Density
1.2360g/cm3
Appearence

3-Fluoropropane-1,2-diol is a colorless liquid. It exhibits properties typical of vicinal diols, which are compounds containing two hydroxyl groups on adjacent carbon atoms. These compounds are often viscous and hygroscopic.

Comment on solubility

Solubility of 3-Fluoropropane-1,2-diol (C3H7FO2)

The solubility of 3-fluoropropane-1,2-diol is an intriguing aspect of its chemical behavior. As a small organic molecule that contains both hydroxyl (–OH) and fluorine groups, its solubility profile is influenced by several factors:

  • Polarity: The presence of hydroxyl groups contributes to the overall polarity of the molecule, enhancing its ability to interact with polar solvents, especially water.
  • Hydrogen Bonding: The –OH groups can form hydrogen bonds, which significantly increases solubility in polar solvents.
  • Fluorine Atom: The electronegative fluorine atom can alter the molecule's interaction with solvents, affecting how well it dissolves.

Overall, 3-fluoropropane-1,2-diol is expected to be soluble in water due to these features, making it suitable for a variety of applications in chemical synthesis where solubility plays a crucial role. To summarize:

  1. High solubility in polar solvents like water.
  2. Enhanced solubility due to hydrogen bonding capabilities.
  3. Interactions affected by the presence of the fluorine atom.

In conclusion, the unique structure of 3-fluoropropane-1,2-diol facilitates its solubility, contributing to its versatility in various chemical processes.

Interesting facts

Interesting Facts about 3-Fluoropropane-1,2-diol

3-Fluoropropane-1,2-diol is a fascinating compound that belongs to a class of substances known as glycerols. Its unique structure and properties make it noteworthy for various applications in scientific research and industry.

Key Characteristics

  • Fluorine Substitution: The presence of fluorine in this compound is significant. It can enhance the reactivity and stability of certain functional groups, making the compound useful in synthetic chemistry.
  • Biocompatibility: Due its alcohol groups, 3-fluoropropane-1,2-diol is expected to exhibit excellent biocompatibility, which is essential for applications in pharmaceuticals and biomedical research.
  • Versatile Solvent: This compound may serve as an efficient solvent, particularly in reactions that require polar protic solvents. Its application extends to the formulation of various chemical products.

Research and Applications

In recent studies, 3Fluoropropane-1,2-diol has gained attention for several reasons:

  • As a potential reagent in the synthesis of fluorinated compounds, which are valuable in materials science and pharmacology.
  • Its role in stabilizing certain chemical reactions due to its ability to engage in hydrogen bonding.

As quoted by researchers, "The introduction of fluorine often leads to compounds exhibiting unique biological activity and improved pharmacokinetics." This highlights the importance of fluorinated compounds in drug design and development.

Conclusion

3-Fluoropropane-1,2-diol exemplifies how small structural changes can lead to significant variations in properties and applications. Its multifaceted roles make it an interesting subject of study for chemists and researchers alike. With ongoing advancements in synthetic methodologies, the potential for discovering new applications continues to grow.

Synonyms
3-fluoropropane-1,2-diol
453-16-7
3-Fluoro-1,2-propanediol
1,2-Propanediol,3-fluoro-
Fluorodeoxyglycerol
DTXSID10941218
1947-57-5
alpha-Fluorohydrin
NSC21306
1, 3-fluoro-
1-deoxy-1-fluoroglycerol
WLN: F1YQ1Q
WLN: Q1YQ1F
CHEMBL3276496
PQDNJBQKAXAXBQ-UHFFFAOYSA-N
DTXCID401369661
MFCD00075515
NSC-21306
AKOS006229068
AT22386
SB83754
CS-0354804
EN300-1846842
630-612-9