Skip to main content

Phenobarbital

ADVERTISEMENT
Identification
Molecular formula
C12H12N2O3
CAS number
50-06-6
IUPAC name
3-ethyl-5-phenyl-imidazolidine-2,4-dione
State
State
Phenobarbital is generally in a solid state at room temperature.
Melting point (Celsius)
175.00
Melting point (Kelvin)
448.00
Boiling point (Celsius)
311.60
Boiling point (Kelvin)
584.80
General information
Molecular weight
232.24g/mol
Molar mass
232.2670g/mol
Density
1.1000g/cm3
Appearence

Phenobarbital typically appears as white, crystalline powder which is odorless. It is sparingly soluble in water and freely soluble in alcohol.

Comment on solubility

Solubility of 3-ethyl-5-phenyl-imidazolidine-2,4-dione (C12H12N2O3)

The solubility of 3-ethyl-5-phenyl-imidazolidine-2,4-dione is an important characteristic that determines its behavior in various chemical environments. While data on the solubility of this compound can be limited, it is often influenced by the following factors:

  • Polarity: The presence of polar functional groups affects how well the compound interacts with solvents.
  • Temperature: Increased temperature typically enhances solubility, making it crucial to consider under specific conditions.
  • pH: The solubility can vary with changes in pH, especially if the compound can ionize under differing conditions.
  • Solvent Choice: Common solvents include water, ethanol, and dimethyl sulfoxide (DMSO); the choice can greatly influence solubility.

Due to its unique structure, 3-ethyl-5-phenyl-imidazolidine-2,4-dione may exhibit moderate solubility in organic solvents while being sparingly soluble in water. It is essential to conduct empirical studies to determine specific solubility values, as these can vary based on experimental conditions.

In conclusion, understanding the solubility of C12H12N2O3 not only aids in predicting its chemical behavior but also enhances its applicability in various scientific and industrial fields.

Interesting facts

Interesting Facts about 3-Ethyl-5-phenyl-imidazolidine-2,4-dione

3-Ethyl-5-phenyl-imidazolidine-2,4-dione, also known as an important derivative in the realm of heterocyclic compounds, has a variety of intriguing applications and properties that make it a point of interest in both organic chemistry and pharmaceuticals.

1. Structure and Functionality

  • The compound contains a unique imidazolidine ring, characterized by its five-membered structure that includes nitrogen atoms.
  • It features both ethyl and phenyl substituents, which can influence the compound's reactivity and solubility profiles.

2. Pharmaceutical Relevance

This compound is significant in medicinal chemistry due to its potential applications in drug development. Some highlights include:

  • Possibility of serving as a precursor in synthesizing novel drug molecules.
  • Potential activity as an anti-inflammatory agent, making it of interest for treating various health conditions.

3. Synthetic Pathways

The synthesis of 3-ethyl-5-phenyl-imidazolidine-2,4-dione can involve several strategies, often focusing on:

  • Condensation reactions that build the imidazolidine framework.
  • Functional group modifications that allow for diverse derivatives to be formed, broadening the applications of this compound.

4. Quote from Experts

As noted by many chemists, “Understanding the derivatives of compounds like 3-ethyl-5-phenyl-imidazolidine-2,4-dione opens new avenues in the pharmaceutical sector.” This highlights the importance of exploring related structures for innovative solutions.

This compound serves as a fascinating example of the intersection of structural chemistry and medicinal applications, illustrating how small variations in chemical structure can lead to significant differences in biological activity and therapeutic potential.

Synonyms
ethotoin
86-35-1
Peganone
Accenon
3-Ethyl-5-phenylhydantoin
Ethotoine
Etotoina
3-ethyl-5-phenylimidazolidine-2,4-dione
Ethotoinum
Ethotoine [INN-French]
Ethotoinum [INN-Latin]
Etotoina [INN-Spanish]
3-Ethyl-5-phenylimidazolidin-2,4-dione
1-Ethyl-2,5-dioxo-4-phenylimidazolidine
3-Ethyl-5-phenyl-2,4-imidazolidinedione
Hydantoin, 3-ethyl-5-phenyl-
2,4-Imidazolidinedione, 3-ethyl-5-phenyl-
HSDB 3580
(+-)-3-Ethyl-5-phenylhydantoin
EINECS 201-665-1
UNII-46QG38NC4U
NSC-760074
BRN 0188272
46QG38NC4U
CHEBI:4888
DTXSID6023020
AC-695; Accenon
(+/-)-3-ethyl-5-phenylhydantoin
3-ethyl-5-phenyl-imidazolidine-2,4-dione
DTXCID903020
Ethotoin [USP:INN:BAN:JAN]
5-24-08-00005 (Beilstein Handbook Reference)
NSC 760074
Pegoanone
Ethotoine (INN-French)
Ethotoinum (INN-Latin)
Etotoina (INN-Spanish)
ETHOTOIN (MART.)
ETHOTOIN [MART.]
ETHOTOIN (USP-RS)
ETHOTOIN [USP-RS]
ETHOTOIN (USP MONOGRAPH)
Ethotoin (USP:INN:BAN:JAN)
ETHOTOIN [USP MONOGRAPH]
2,4-IMIDAZOLIDINEDIONE, 3-ETHYL-5-PHENYL-, (+/-)-
Peganone (TN)
Accenon (TN)
Ethotoin (JAN/USP/INN)
CAS-86-35-1
NCGC00016340-01
Ethotoin (Standard)
MFCD00072127
ETHOTOIN [HSDB]
ETHOTOIN [INN]
ETHOTOIN [JAN]
ETHOTOIN [MI]
ETHOTOIN [VANDF]
(.+/-.)-Ethotoin
Prestwick0_000696
Prestwick1_000696
Prestwick2_000696
Prestwick3_000696
ETHOTOIN [WHO-DD]
CHEMBL1095
Oprea1_374844
SCHEMBL34301
BSPBio_000851
MLS002153961
SPBio_002772
ETHOTOIN (200 MG)
ETHOTOIN [ORANGE BOOK]
2,4-Imidazolidinedione, 3-ethyl-5-phenyl-, (+-)-
BPBio1_000937
GTPL7183
HY-B1642R
N03AB01
HMS1570K13
HMS2097K13
HMS2232M06
HMS3371O03
HMS3714K13
HMS3887I05
Pharmakon1600-01505428
AAA08635
HY-B1642
Tox21_110383
NSC760074
AKOS008947805
CCG-213433
DB00754
NCGC00179401-01
NCGC00179401-03
DA-53024
NS-02146
SMR001233300
3-Ethyl-5-phenyl-2,4-imidazolidinedione #
AB00513897
CS-0013593
NS00039122
C07839
D00708
EN300-938193
F88162
AB00513897_07
SR-01000841832
Q4533122
SR-01000841832-2
BRD-A30205217-001-11-2
BRD-A30205217-001-12-0
Z53845223
1-ethyl-2-hydroxy-4-phenyl-4,5-dihydro-1H-imidazol-5-one
201-665-1