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3-ethyl-5-methyl-glutarimide

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Identification
Molecular formula
C9H15NO2
CAS number
3247-40-1
IUPAC name
3-ethyl-5-methyl-piperidine-2,6-dione
State
State

At room temperature, the compound is typically found in a solid state. Due to its crystalline nature, it maintains structural integrity unless subjected to temperatures above its melting point. It is stable under standard conditions of pressure and temperature.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
169.21g/mol
Molar mass
169.2140g/mol
Density
1.0570g/cm3
Appearence

3-Ethyl-5-methyl-piperidine-2,6-dione appears as a crystalline solid. The compound typically has a white to off-white color, depending on the purity and specific conditions. The crystalline structure can vary slightly, but it generally forms fine needles or larger, more defined crystals under controlled crystallization processes.

Comment on solubility

Solubility of 3-ethyl-5-methyl-piperidine-2,6-dione (C9H15NO2)

The solubility of 3-ethyl-5-methyl-piperidine-2,6-dione is influenced by several factors that determine how well this compound dissolves in various solvents. To understand its solubility, we can consider the following:

  • Polarity: The presence of polar functional groups such as the carbonyl groups (C=O) in the piperidine-2,6-dione structure tends to enhance solubility in polar solvents, particularly water.
  • Hydrophobic Character: The ethyl and methyl groups contribute hydrophobic characteristics, which may hinder solubility in highly polar solvents.
  • Temperature: Increasing temperature often enhances the solubility of organic compounds due to increased molecular motion, allowing for more interactions with the solvent.
  • pH Considerations: As a small organic molecule, the pH of the solution can affect its ionization state, which in turn may affect solubility. However, this compound does not have acidic or basic groups to significantly alter its solubility under normal conditions.

In summary, while 3-ethyl-5-methyl-piperidine-2,6-dione demonstrates favorable solubility characteristics in moderately polar solvents, its hydrophobic components can limit its solubility in highly polar environments. This makes understanding the specific context of use essential when predicting how this compound will behave in solution.

Interesting facts

Interesting Facts about 3-Ethyl-5-methyl-piperidine-2,6-dione

3-Ethyl-5-methyl-piperidine-2,6-dione is a fascinating compound that falls within the class of piperidine derivatives. This compound is particularly interesting for several reasons:

  • Diverse Applications: The structural framework of 3-ethyl-5-methyl-piperidine-2,6-dione makes it a valuable intermediate in organic synthesis. It is often used in the production of pharmaceuticals, fine chemicals, and agrochemicals.
  • Biological Activity: Research has indicated that piperidine derivatives can exhibit a wide range of biological activities, including antimicrobial, anti-inflammatory, and even antidepressant properties. Thus, compounds like 3-ethyl-5-methyl-piperidine-2,6-dione hold potential for new drug discovery.
  • Piperidine Ring: The presence of the piperidine ring in its structure is significant as piperidine is a basic nitrogen-containing heterocycle. Its nitrogen atom can participate in various reactions, enhancing its utility in synthetic organic chemistry.
  • Synthesis Pathways: There are multiple synthesis pathways for creating 3-ethyl-5-methyl-piperidine-2,6-dione. Understanding these methods not only sheds light on its chemical behavior but also provides insights into reaction mechanisms vital for aspiring chemists.

In addition to its practical use in synthesis, 3-ethyl-5-methyl-piperidine-2,6-dione serves as a model for studying structure-activity relationships. As chemists manipulate its structure, they can contribute to the design of new compounds with enhanced therapeutic effects.

In summary, 3-ethyl-5-methyl-piperidine-2,6-dione embodies the intersection of synthesis, application, and biological importance, making it a truly remarkable compound in the world of chemistry.

Synonyms
p-ethyl-methylglutarimide
NSC159012
NSC-159012