3-Ethyl-4-oxo-1-(p-tolylsulfonyl)azetidine-2-carboxylic acid

Identification

Molecular formula

C₁₃H₁₅NO₅S

CAS number

IUPAC name

3-ethyl-4-oxo-1-(p-tolylsulfonyl)azetidine-2-carboxylic acid

State

Solid at room temperature, typically in the form of crystalline powder.

Melting point (Celsius)

215.00

Melting point (Kelvin)

488.00

Boiling point (Celsius)

580.00

Boiling point (Kelvin)

853.00

General information

Molecular weight

297.34g/mol

Molar mass

297.3410g/mol

Density

1.3200g/cm³

Appearence

This compound is typically a white to off-white crystalline solid. Its appearance can vary slightly depending on the exact method of preparation and the presence of any impurities.

Comment on solubility

Solubility of 3-ethyl-4-oxo-1-(p-tolylsulfonyl)azetidine-2-carboxylic acid

The solubility of 3-ethyl-4-oxo-1-(p-tolylsulfonyl)azetidine-2-carboxylic acid (C₁₃H₁₅NO₅S) is influenced by several key factors:

Polarity: This compound possesses polar functional groups, including a carboxylic acid and a sulfonyl group, which typically enhances its solubility in polar solvents such as water.
Hydrogen Bonding: The presence of –COOH (carboxylic acid) contributes to the ability to form hydrogen bonds, further facilitating solubility in water.
Aromatic Interactions: The presence of the p-tolyl group suggests that aromatic interactions may occur, which can impact solubility in nonpolar solvents.
Temperature Dependent: Like many organic compounds, solubility may increase with temperature; thus, solubility assessments should consider this variable for accurate results.

In summary, while this compound is expected to be relatively soluble in polar solvents due to its functional groups, the actual solubility may vary based on specific environmental conditions, such as the solvent used and temperature. To maximize solubility, it is recommended to consult experimental data when working with this compound.

Interesting facts

Interesting Facts about 3-ethyl-4-oxo-1-(p-tolylsulfonyl)azetidine-2-carboxylic acid

This compound, 3-ethyl-4-oxo-1-(p-tolylsulfonyl)azetidine-2-carboxylic acid, showcases the fascinating intersection of organic chemistry and medicinal applications. Here are some noteworthy points:

Structural Diversity: The azetidine ring structure provides a unique framework that contributes to the compound's biological activity. Such nitrogen-containing heterocycles are often found in pharmaceuticals.
Functional Groups: The presence of both a carboxylic acid and a sulfonyl group enhances the compound’s reactivity and interactions in biological systems. This makes it a potential candidate for drug development.
Antimicrobial Potential: Compounds similar to this azetidine derivative have been studied for their antimicrobial properties. It is crucial to investigate whether this chemical could exhibit similar activity.
Synthetic Pathways: The synthesis of such compounds is a topic of ongoing research, often involving multi-step processes that could involve various reagents and catalysts, showcasing the complexity and creativity in organic synthesis.
Applications in Chemistry: Researchers continue to explore the versatility of azetidine derivatives in creating novel compounds. This may lead to significant advancements in pharmaceuticals, especially in treating different diseases.

As the study of such compounds progresses, chemists remain eager to uncover the broad spectrum of activities they may possess, opening new avenues for therapeutic development.

Synonyms

CHEMBL153109

PD194826