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3-(dipropylamino)tetralin-6-ol

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Identification
Molecular formula
C16H25NO
CAS number
127487-95-6
IUPAC name
3-(dipropylamino)tetralin-6-ol
State
State

At room temperature, 3-(dipropylamino)tetralin-6-ol is typically in a liquid state. It is important to note that its state might change under different temperatures and pressures.

Melting point (Celsius)
69.00
Melting point (Kelvin)
342.00
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.00
General information
Molecular weight
261.41g/mol
Molar mass
261.4140g/mol
Density
0.9825g/cm3
Appearence

The compound 3-(dipropylamino)tetralin-6-ol is typically a liquid that may appear colorless or slightly yellowish depending on purity levels and storage conditions. It is important to store it away from light and moisture to maintain its integrity.

Comment on solubility

Solubility of 3-(Dipropylamino)tetralin-6-ol (C16H25NO)

The solubility of 3-(dipropylamino)tetralin-6-ol can be characterized based on its molecular structure and functional groups. This compound exhibits interesting solubility properties, which can be outlined as follows:

  • Polar vs. Nonpolar: The presence of the amino group contributes to some degree of polarity, while the tetralin ring structure and alkyl chains lean towards hydrophobic characteristics.
  • Solvent Interaction: It is likely to be soluble in organic solvents such as ethanol, methanol, and other polar organic solvents, but its solubility in water is expected to be limited due to the nonpolar nature of the alkyl chains.
  • Hydrogen Bonding: The amino group can form hydrogen bonds, which enhances its solubility in certain solvents but may also be a factor that decreases solubility in water at higher concentrations.
  • Temperature Dependence: As with many organic compounds, solubility may increase with temperature, providing enhanced dissolution in organic solvents.

In summary, the solubility of 3-(dipropylamino)tetralin-6-ol is a balance between its polar (due to the amino group) and nonpolar (due to the tetralin and alkyl groups) character, making it more compatible with non-aqueous solvents while posing challenges in aqueous environments. This balance is crucial when considering its applications and behavior in different chemical contexts.

Interesting facts

Interesting Facts about 3-(Dipropylamino)tetralin-6-ol

3-(Dipropylamino)tetralin-6-ol is a fascinating compound with a unique structure and a variety of interesting properties. Here are some key points that highlight its significance in the field of chemistry:

  • Structural Characteristics: This compound features a tetralin core, which is a bicyclic structure that contributes to its interesting chemical behavior. The presence of a dipropylamino group on the 3-position enhances its potential for various interactions.
  • Pharmacological Interest: Compounds similar to 3-(dipropylamino)tetralin-6-ol have shown promise in pharmacological studies. Their potential use as antidepressants or anti-anxiety medications makes them of significant interest in medicinal chemistry.
  • Investigation of Neurotransmitter Systems: The structure of this compound suggests that it may interact with neurotransmitter systems, particularly those involving serotonin and norepinephrine. Such interactions could potentially lead to innovative treatments for mood disorders.
  • Synthetic Pathways: The synthesis of 3-(dipropylamino)tetralin-6-ol can be achieved through various organic reactions, showcasing the versatility of organic synthesis techniques. This offers valuable insights into synthetic chemistry and the development of new compounds.
  • Comparative Analysis: Studying this compound alongside others can reveal important trends in how structural changes affect biological activity. It’s a great example of structure-activity relationship (SAR) studies.

Overall, 3-(dipropylamino)tetralin-6-ol exemplifies how intricate chemical structures can lead to significant biological effects, serving as a reminder of the importance of chemistry in developing new therapeutic agents. As we continue to explore these compounds, we unlock the potential for breakthroughs in medicine that can improve lives.

Synonyms
7-OH-DPAT
74938-11-7
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
DP-7-AT
7-Hydroxy-2-N,N-dipropylaminotetralin
7-Hydroxy-N,N-di-n-propyl-2-aminotetralin
2-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-
[3H]7-OH-DPAT
7-hydroxy-2-(di-n-propylamino)tetralin
RR7D75YDF4
7-(Dipropylamino)-5,6,7,8-tetrahydro-2-naphthalenol
CHEMBL285755
7-Ohdpat
(+)-7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol hydrobromide
N,N-Di-n-propyl-7-hydroxy-2-aminotetralin
UNII-RR7D75YDF4
(+)7-OH-DPAT
[3H]-7-OH-DPAT
Biomol-NT_000011
7-Hydroxy-DPAT middot HBr
Lopac0_000616
GTPL950
SCHEMBL623950
(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin
BPBio1_001143
GTPL3296
7-OH-DPAT,(+)
7-OH-DPAT,(-)
DTXSID00874864
CHEBI:111176
(+/-)-7-OH-DPAT
2-Naphthalenol,7-(dipropylamino)-5,6,7,8-tetrahydro-,(S)
7-hydroxy-2-(dipropylamino)tetralin
(7S)-7-(DIPROPYLAMINO)-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL
BDBM50020222
PDSP1_001643
PDSP2_001627
AKOS015913437
CCG-204705
SDCCGSBI-0050598.P002
NCGC00015494-04
NCGC00015494-05
NCGC00015494-06
NCGC00015494-11
NCGC00024742-02
NCGC00024742-03
2-(DI-N-PROPYLAMINO)-7-HYDROXYTETRALIN
7-HYDROXY-N,N-DIPROPYL-2-AMINOTETRALIN
N,N-DIPROPYL-7-HYDROXY-2-AMINOTETRALIN
L000014
Q6593984
BRD-A18795974-001-01-2
BRD-A18795974-004-02-4
BRD-A18795974-004-07-3
7-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN, (+/-)-
(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)