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3-(dipropylamino)tetralin-5-ol

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Identification
Molecular formula
C17H29NO
CAS number
107198-79-8
IUPAC name
3-(dipropylamino)tetralin-5-ol
State
State

The compound is liquid at room temperature, exhibiting characteristics typical of organic amines. It is not particularly viscous and tends to remain in liquid form unless cooled below its melting point.

Melting point (Celsius)
34.00
Melting point (Kelvin)
307.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
261.42g/mol
Molar mass
261.4020g/mol
Density
1.0633g/cm3
Appearence

The compound typically appears as a colorless or pale yellow oil. It may have a mild amine-like odor and is usually clear in appearance without any suspended particles or turbidity.

Comment on solubility

Solubility of 3-(Dipropylamino)tetralin-5-ol

3-(Dipropylamino)tetralin-5-ol, with the chemical formula C17H29NO, presents an interesting case in terms of solubility characteristics. The solubility of this compound is influenced by several factors:

  • Polarity: The presence of the hydroxyl (-OH) group contributes to its polar nature, which can enhance solubility in polar solvents.
  • Alkyl Chains: The dipropylamino group introduces hydrophobic characteristics that can affect solubility in non-polar solvents.
  • Hydrogen Bonding: The ability of the -OH group to engage in hydrogen bonding can significantly increase solubility in water compared to its non-alcohol analogs.

As a result, one might see the following solubility trends:

  • Soluble in: Alcohols, such as ethanol or methanol, due to hydrogen bonding capabilities.
  • Moderately soluble in: Water, depending on concentration and temperature.
  • Insoluble in: Non-polar solvents like hexane, where the hydrophobic nature dominates.

In conclusion, the solubility of 3-(dipropylamino)tetralin-5-ol is a balance between its polar -OH group and the hydrophobic alkyl chains, making it an intriguing compound for various applications in chemical studies.

Interesting facts

Interesting Facts About 3-(Dipropylamino)tetralin-5-ol

3-(Dipropylamino)tetralin-5-ol, a fascinating compound, has sparked interest in various fields due to its unique structure and potential applications. Here are some captivating insights:

  • Structural Complexity: The presence of the dipropylamino group attached to the tetralin core introduces a remarkable level of structural diversity. This complexity can lead to varied interactions with biological systems.
  • Potential Pharmacological Applications: Due to its structural composition, 3-(dipropylamino)tetralin-5-ol is an intriguing candidate for drug discovery, particularly in the realm of neuropharmacology. Compounds similar to this have been investigated for their effects on the central nervous system.
  • Synthesis Considerations: The synthesis of this compound can take advantage of various organic reactions such as amination and hydroxylation processes. Understanding these pathways helps chemists to design more efficient synthetic routes.
  • Research Relevance: Studies often explore the selectivity and binding characteristics of such compounds with neurotransmitter receptors, like dopamine or serotonin, which can elucidate their behavior in pharmacological contexts.
  • Analytical Techniques: Characterizing this compound may involve advanced analytical methods, such as NMR (Nuclear Magnetic Resonance) spectroscopy and mass spectrometry, enabling chemists to confirm its structure and investigate its properties.

In summary, 3-(dipropylamino)tetralin-5-ol serves as more than just a chemical entity; it embodies the marriage of organic chemistry with medicinal research, showcasing the intricate dance between structure and function in the quest for new therapeutic agents.

Synonyms
8-OH-Dpat
78950-78-4
8-HYDROXY-2-(DI-n-PROPYLAMINO)TETRALIN
8-Hydroxy-DPAT
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
1-Naphthalenol,7-(dipropylamino)-5,6,7,8-tetrahydro-
1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-
DPAT
CHEBI:73364
(+-)-8-OH-DPAT
CHEMBL56
dl-8-Hydroxy-2-(dipropylamino)tetralin
IWS1724PX6
DTXSID30897384
78950-78-4 (free base)
S(-)-8-HYDROXY-DPAT HYDROBROMIDE PARTIAL 5-HT1A SECROT
[3H]-8-OH-DPAT
80300-09-0
R(+)-8-OH-dpat
UNII-IWS1724PX6
(R)-8-Hydroxy-2-dipropylaminotetralin
8-hydroxy-n,n-dipropyl-2-aminotetralin
8OHDPAT
GTPL7
Biomol-NT_000095
GTPL31
cid_1220
8-OH-DPAT?
Lopac0_000576
(+/-)-8-HYDROXY-2-DIPROPYL-AMINOTETRALIN
SCHEMBL496783
BPBio1_001354
8-Hydroxy-DPAT; 8OH-DPAT
S(-)-8-OH-DPAT HBr
8-OH-DPAT,(+)
8-OH-DPAT,(-)
BDBM21393
DTXCID00834185
TQP0825
ASXGJMSKWNBENU-UHFFFAOYSA-N
(+/-)-8-OH-DPAT
HMS3886N10
8-OH-DPAT (8-Hydroxy-DPAT)
8-hydroxy-n,n-dipropylaminotetralin
BCP25681
EX-A2914
MFCD00153811
PDSP1_000777
PDSP2_000765
AKOS030627213
CCG-204665
SDCCGSBI-0050558.P002
NCGC00015493-04
NCGC00015493-05
NCGC00015493-06
NCGC00015493-10
NCGC00024635-02
NCGC00024635-03
NCGC00024986-02
BO166474
MS-23507
DB-018083
DB-108186
HY-112061
(+/-)-8-Hydroxy-2-(dipropylamino)tetralin
CS-0043224
S8447
G12802
(+/-)-8-hydroxy-2-(di-n-propylamino)tetralin
L000086
Q4644282
SR-01000075571-7
5,6,7,8-tetrahydro-7-(dipropylamino)-1-naphthalenol
BRD-A48015106-001-01-0
BRD-A48015106-004-03-0
BRD-A48015106-004-08-9
(+/-)-8-HYDROXY-N,N-DIPROPYL-2-AMINOTETRALIN
8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN, (+/-)-
(+/-)-7-(DIPROPYLAMINO)-5,6,7,8-TETRAHYDRO-1-NAPHTHALENOL
(+/-)-7-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol; (+/-)-8-Hydroxy-2-(dipropylamino)tetralin(+/-)-8-Hydroxy-N,N-dipropyl-2-aminotetralin
105558-30-3