3-(dipropylamino)-8-fluoro-tetralin-5-ol

Identification

Molecular formula

C₁₇H₂₄FNO

CAS number

IUPAC name

3-(dipropylamino)-8-fluoro-tetralin-5-ol

State

The compound exists as a solid at room temperature under standard conditions. It maintains its structure and remains in solid state until it is heated to its melting point.

Melting point (Celsius)

156.00

Melting point (Kelvin)

429.15

Boiling point (Celsius)

376.00

Boiling point (Kelvin)

649.15

General information

Molecular weight

291.39g/mol

Molar mass

291.3880g/mol

Density

1.1200g/cm³

Appearence

3-(dipropylamino)-8-fluoro-tetralin-5-ol is typically observed as a crystalline solid. The color can range from white to a light beige depending on its purity and specific sample conditions. The compound is known to be hygroscopic and should be handled carefully to avoid absorption of moisture from the environment.

Comment on solubility

Solubility of 3-(dipropylamino)-8-fluoro-tetralin-5-ol

The solubility of 3-(dipropylamino)-8-fluoro-tetralin-5-ol (C₁₇H₂₄FNO) can significantly influence its applications in various chemical and pharmaceutical contexts. Understanding the solubility characteristics is essential for effective formulation and utilization. Here are some key points regarding its solubility:

Polar vs. Nonpolar: Due to the presence of the dipropylamino group, the compound exhibits both polar and nonpolar characteristics, suggesting that it may dissolve in a variety of solvents.
Solubility in Water: The overall solubility in water may be limited given the largely hydrophobic nature of the carbon chains in the dipropylamino moiety.
Organic Solvents: This compound is likely to be more soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) due to its nonpolar sections.
Temperature Dependence: Like many organic compounds, solubility can be influenced by temperature; increasing the temperature may enhance solubility in certain solvents.

In summary, while 3-(dipropylamino)-8-fluoro-tetralin-5-ol shows some potential for solubility in both polar and nonpolar environments, its practicality in aqueous solutions might be limited. As a general rule in chemistry, "the structure dictates solubility," and understanding this compound's unique structure will provide a clearer insight into its behavior in various solution environments.

Interesting facts

Interesting Facts About 3-(Dipropylamino)-8-Fluoro-Tetralin-5-Ol

3-(Dipropylamino)-8-fluoro-tetralin-5-ol is a fascinating compound that intersects various fields of chemistry and pharmacology. Below are some key insights that highlight its significance:

Structure and Function: This compound features a fluorine atom, which is known for imparting unique electronic properties, influencing both the biological activity and the physicochemical characteristics of the compound.
Biological Activity: Compounds like this one have gained interest as potential therapeutic agents. The modifications in the tetralin structure can lead to varying interactions with biological targets, making it a subject of study in medicinal chemistry.
Amine Functionality: The dipropylamino group is significant in pharmacology; it is often associated with increased lipophilicity, which can influence how well the compound crosses biological membranes.
Fluorine's Role: The incorporation of fluorine in organic molecules often enhances their metabolic stability and can affect binding affinity to certain receptors. This is particularly interesting in drug design, where optimizing efficacy while minimizing side effects is key.
Research Applications: This compound could be explored in the development of drugs targeting the central nervous system, given its unique structural features. Its potential as an antidepressant or for treating anxiety disorders may warrant further research.

In conclusion, 3-(dipropylamino)-8-fluoro-tetralin-5-ol exemplifies how small changes in molecular structure can have profound effects on biological activity and the compound's overall utility in therapeutic applications. As researchers continue to unveil the depths of chemistry, compounds like this one will undoubtedly play crucial roles in advancing science.

Synonyms

5-Fluoro-8-hydroxy-2-(dipropylamino)tetralin

7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-ol

ACMC-20msc3

AC1L1JNP

AC1Q4NWP

CHEBI:9847

SCHEMBL5658545

3-(dipropylamino)-8-fluoro-tetralin-5-ol

L000008

5-Fluoro-8-hydroxy-2-dipropylamino-1,2,3,4-tetrahydronaphthalin